Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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Diuretic Ultrasound Evaluation of Surgical Necessity in Pediatric Ureteropelvic Junction Obstruction.

RATIONALE AND OBJECTIVES: This study aimed to develop an interpretable machine learning (ML) model using diuretic ultrasonography to predict the necessity for surgical intervention in children aged 1 month to 18 years with ureteropelvic junction obstruction (UPJO), thereby providing a non-invasive, radiation-free approach to optimize clinical decision-making. MATERIALS AND METHODS: This study incl...

May 5 2026 42091396

Evaluation of Large-Language Models for Structured Feature Extraction of Anatomic and Clinical Pathology Reports.

BACKGROUND: Feature extraction via manual chart review is often used for both patient care and research, but it is time-intensive and costly. Recent improvements in natural language processing present novel opportunities to perform high-throughput automated feature extraction. Here, we assessed the accuracy of large language models (LLMs) for structured feature extraction from clinical and anatomi...

May 5 2026 41677051
Prognostic significance of right ventricular myocardial features derived from echocardiography using a deep learning framework in pulmonary arterial hypertension.

BACKGROUND: The function and myocardial characteristics of the right ventricle (RV) are linked to RV dysfunction and prognosis in pulmonary arterial h...

May 5 2026 42085337
Global research trends in artificial kidneys (2014-2024): A bibliometric and visualization study.

When renal function is lost following resection of renal tumors, in the setting of end-stage kidney disease, or after traumatic nephrectomy, kidney tr...

May 5 2026 42086515
Comprehensive evaluation of cross cancer generalization in histopathology segmentation models across 21 tumor types.

BACKGROUND: Artificial intelligence has significantly advanced computational pathology by enabling high-resolution, clinical-grade tumor segmentation ...

May 5 2026 42086725
Early identification of high-risk individuals for mortality after lung transplantation: A retrospective cohort study with topological feature engineering.

Lung transplantation remains the only definitive treatment for end-stage respiratory failure; however, it has substantial post-operative mortality ris...

May 5 2026 42085469
Neutrophil extracellular traps-related biomarkers in idiopathic pulmonary arterial hypertension: A machine learning-based identification and experimental validation study.

Neutrophil extracellular traps (NETs) are increasingly recognized as critical mediators in vascular inflammation and remodeling, yet their molecular m...

May 4 2026 42085826
Machine learning predicts postoperative mortality in a Latin American cardiovascular surgery multicenter cohort: Toward precision risk stratification.

OBJECTIVE: A total of 28% of global cardiac surgeries are performed in Latin America; however, surgeons there are faced with many preventable deaths, ...

May 4 2026 42080776
Flexible Strain-Temperature Dual-Modal Smart Patch Based on 3D Printing for Wound Healing Promotion and Health Monitoring.

For patients with open joint wounds, postoperative rehabilitation requires real-time and reliable monitoring of physiological parameters. Conventional...

May 4 2026 42080925
Supervised Learning for Collagen Segmentation in Bright-Field Histology: A Comparative Evaluation of U-Net and MLP.

PURPOSE: Quantifying collagen in histological slides is essential for diagnosing and monitoring fibrosis. However, the combination of PicroSirius Red ...

May 4 2026 42081149
Multimodal deep learning model for multiclass classification of renal tumors.

Accurate classification of renal masses before treatment is crucial for therapeutic decision-making and patient outcome. This study developed and vali...

May 4 2026 42082763
Identification of potential biomarkers for osteoporosis and chronic kidney disease through bioinformatics and machine learning algorithm.

OBJECTIVE: The purpose of this study is to identify hub genes associated with both osteoporosis (OP) and chronic kidney disease (CKD) through bioinfor...

May 4 2026 42081554
Contemporary heart failure evidence in 2025: a joint summary of key trials from the European Journal of Heart Failure and ESC Heart Failure Journal.

Heart failure (HF) remains a major global health challenge, characterized by high morbidity, mortality, and healthcare costs despite substantial advan...

May 2 2026 41771104
Identification of MMP14 and FOS as key regulators of vascular smooth muscle cell senescence in diabetic kidney disease: A combined bioinformatics and experimental study.

OBJECTIVE: Diabetic kidney disease (DKD) is a leading microvascular complication of diabetes in which vascular smooth muscle cell (VSMC) senescence pl...

May 1 2026 42107160
An Integrated Clinical-Histopathologic Prediction Model for Cardiac Allograft Rejection: Translating Machine Learning into Clinical Risk Frameworks.

BACKGROUND: Cardiac allograft rejection (CAR) remains the leading cause of early graft failure after heart transplantation (HT). Current diagnostics, ...

May 1 2026 42070726
Personalized assessment of hyperuricemia probability in metabolic dysfunction-associated steatotic liver disease: construction and multicenter validation of a clinical nomogram.

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease is increasingly recognized as a precursor to secondary hyperuricemia, significant...

May 1 2026 42067778
Classifying Kidney Tumor via Adaptive SE-ResNeXt With Mutli-Novel Loss Function and Renal Mass Segmentation Using Pyramidal Attention-Based R2Unet++ Model.

Kidney tumors are one of the prevalent types of tumor globally and it has become a significant health concern. It is the most frequent type of urologi...

May 1 2026 42043283
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold-Mediated Regulation.

Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, se...

May 1 2026 42045927
Cross-attention multimodal fusion for EGFR mutation prediction: A predictive model using CT and whole-slide images.

BACKGROUND: The prediction of Epidermal Growth Factor Receptor (EGFR) mutation status in advanced lung adenocarcinoma is crucial for targeted therapy....

May 1 2026 42050780
Combined Effects of Long-Term Sulfur Dioxide Exposure and Environmental Heat Stress on the Risk of Kidney Stone Disease.

OBJECTIVES: Kidney stone disease is influenced by environmental, metabolic, and climatic factors. Although sulfur dioxide and environmental heat stres...

May 1 2026 42057588
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