Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Exploring cognitive workload recognition using CogRepLKNet with EEG-fMRI.

Accurate multimodal Cognitive Workload Recognition (CWR) remains challenging due to the difficulty of modeling cross-modal relationships between Electroencephalography (EEG) and Functional Magnetic Resonance Imaging (fMRI) data. Additionally, the inherent heterogeneity of these physiological signals-each capturing distinct neural characteristics-complicates unified feature extraction. To address t...

Jan 10 2026 41544500

A causal bidirectional selective state space model for imaging genetics in neurodegenerative diseases.

Brain imaging genetics aims to uncover the pathological mechanisms and improve the diagnosis of brain diseases, particularly neurodegenerative disorders. While deep learning has advanced feature extraction and association modeling in this field, there are still two major challenges: extracting meaningful information from long genetic sequences and establishing causal relationships among genetics, ...

Jan 10 2026 41547121
A Novel Acetylcholine Nanosensor for Single Vesicle Storage and Sub-Quantal Exocytosis in Living Neurons and Organoids.

Acetylcholine (ACh) is a critical neurotransmitter that regulates diverse physiological functions, such as cognition and muscle contraction, through s...

Jan 10 2026 41518282
Bergenin attenuates traumatic brain injury via inhibition of microglial PFKFB3-driven glycolytic-inflammatory crosstalk.

Traumatic brain injury (TBI) initiates a complex cascade of neuroinflammatory and metabolic disturbances that exacerbate neuronal loss and neurologica...

Jan 10 2026 41520557
An Ensemble Learning Artificial Intelligence Model for Alzheimer's Disease Detection Using OCT.

PURPOSE: There has been significant progress in detecting Alzheimer's disease (AD) using retinal imaging. We developed an ensemble learning-based deep...

Jan 10 2026 41717239
Designing Soft Arms with Octopus-Like Dexterity: Insights from Magnetic Resonance Imaging and Finite Element Analysis.

Octopuses are capable of remarkably intricate movements without a skeletal framework, making them a compelling model for the design of soft robotic ar...

Jan 9 2026 42423071
Unlocking Insights from Postictal EEGs: Investigating Predictive Markers of Seizure Recurrence.

PURPOSE: Seizure recurrence, often presenting as clusters, is a major clinical concern linked to increased morbidity. The immediate postictal period i...

Jan 9 2026 41514151
Predicting Cerebral Aneurysm Recurrence after Coil Embolization: A Novel Deep Learning Approach Using Time-of-flight Magnetic Resonance Angiography.

The recurrence of cerebral aneurysms after coil embolization remains a significant concern in clinical practice. This study introduced a novel approac...

Jan 9 2026 41526250
A multi-target therapeutic framework for Alzheimer's disease: an integrative mechanistic review.

BACKGROUND: Alzheimer's disease (AD) is increasingly recognized as a multifactorial network disorder in which amyloid and tau pathology interact with ...

Jan 9 2026 41520868
K-means++ guided multi-view CNN with channel attention for EEG emotion recognition.

The use of artificial intelligence for emotion recognition is the focus of improving human-computer interaction. Recently, deep learning has been wide...

Jan 9 2026 41520860
Multimodal MRI integrating anti-motion multi-parametric mappings for investigating subcortical nuclei microstructural alterations in Huntington's disease.

BackgroundHuntington's disease (HD) is a hereditary neurodegenerative disorder, with pathological changes detectable by MRI before symptom onset. Quan...

Jan 8 2026 41505360
Hippocampus-centered structural covariance network reorganization in Alzheimer's disease: An individualized graph-based biomarker validated by machine learning.

Alzheimer's disease (AD) is characterized by progressive brain network disintegration, yet quantifying this process at an individual level remains cha...

Jan 8 2026 41525748
UltraMN: Advancing Real-Time Median Nerve Ultrasound Monitoring With a Multitask Deep Learning Framework.

OBJECTIVE: This study aims to develop an advanced deep learning framework to overcome the challenges associated with real-time ultrasound monitoring o...

Jan 8 2026 41506963
EEG-based schizophrenia classification using attention-integrated deep convolutional networks.

Schizophrenia is a complex psychiatric disorder marked by cognitive and perceptual disruptions, for which electroencephalography (EEG) provides a valu...

Jan 8 2026 41529582
Predictors of Outcome Clusters in Patients With Unruptured Intracranial Aneurysms Treated With Microsurgery: An Unsupervised Machine Learning Analysis.

BACKGROUND AND OBJECTIVES: Identifying surgical candidates who are prone to poor outcomes is crucial for adapting treatment and ensuring optimal outco...

Jan 8 2026 41509178
NeuroDetour: A neural pathway transformer for uncovering structural-functional coupling mechanisms in human connectome.

Although modern imaging methods enable in-vivo examination of connections between distinct brain areas, we still lack a comprehensive understanding of...

Jan 8 2026 41529560
Spatial proteomics in precision medicine: technologies, bioinformatics, and translational applications.

Protein function is inherently spatial: the same molecule can elicit distinct biological outcomes depending on its localization, interacting partners,...

Jan 8 2026 41647441
Comprehensive Analysis of Autophagy-Related Gene Profiles and Immune Characteristics in Parkinson's Disease.

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal loss and α-synuclein pathology, yet the ro...

Jan 8 2026 41505625
MRI-to-PET synthesis via deep learning for amyloid-β quantification in Alzheimer's disease.

OBJECTIVES: Amyloid-β (Aβ) PET is crucial for diagnosing and monitoring Alzheimer's disease (AD), but its high cost and radiation exposure limit its u...

Jan 7 2026 41495456
A unified framework for EEG seizure detection using universum-integrated generalized eigenvalues proximal support vector machine.

The paper presents novel Universum-enhanced classifiers: the Universum Generalized Eigenvalue Proximal Support Vector Machine (U-GEPSVM) and the Impro...

Jan 7 2026 41538899
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