Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Noninvasive Preoperative Evaluation in Drug-Resistant Epilepsy Based on the Brain Network Topological Dynamics.

Drug-resistant epilepsy (DRE) affects over 50 million individuals worldwide, yet surgical resection, the most effective treatment, achieves seizure freedom in only approximately 50% of cases. A reliable, noninvasive method for preoperative surgical outcome prediction is therefore critically needed to avoid the risks of invasive intracranial monitoring. This retrospective study developed a fully no...

Jul 16 2026 42461748

Identifying sex-specific sub-phenotypes of Alzheimer's disease progression using longitudinal electronic health records.

BACKGROUND: Alzheimer's Disease (AD) is a complex neurodegenerative disorder, with women comprising nearly two-thirds of individuals with AD. However, sex-specific heterogeneity in AD progression remains insufficiently understood. A data-driven approach is needed to characterise such heterogeneity from longitudinal electronic health records (EHRs). METHODS: We developed a deep learning-based frame...

Jul 16 2026 42462283
Diagnostic Performance of Deep Learning for Automated Mandibular Canal Segmentation on CBCT Images: A Systematic Review and Meta-Analysis.

INTRODUCTION: Accurate localization of the mandibular canal in Cone-Beam Computed Tomography (CBCT) images is critical for preventing iatrogenic nerve...

Jul 16 2026 42462969
Network-based discovery of regulatory drivers of cognitive decline in alzheimer's disease.

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder marked by progressive cognitive decline, yet its transcriptional regulatory ar...

Jul 16 2026 42463670
Automated detection of trigeminal neuralgia using multi-domain EEG feature analysis and CNN-attention architecture: a comparative machine learning study.

Trigeminal neuralgia (TN) is a debilitating neuropathic pain disorder characterized by sudden, intense facial pain, with diagnosis heavily reliant on ...

Jul 16 2026 42463727
Integrative single-cell and spatial transcriptomics combined with machine learning to discover complement-associated biomarkers in temporal lobe epilepsy with hippocampal sclerosis.

Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) poses significant challenges in therapeutic management. While studies have demonstrated sei...

Jul 16 2026 42458112
Effectiveness and usability of artificial intelligence-powered assistive technologies in Supporting daily activities of children with cerebral palsy: a systematic review.

BACKGROUND: Cerebral Palsy (CP) is the main cause of motor disabilities in childhood, necessitating innovative approaches to rehabilitation and assist...

Jul 15 2026 42458819
From unlabeled to labeled: self-supervised deep learning in computational pathology.

PURPOSE: The advancement of decision support systems for pathology and their implementation in clinical practice have been limited by the necessity fo...

Jul 15 2026 42458576
Leveraging Advanced AI Frameworks for Dual PPAR α/γ Agonist Discovery in Alzheimer's Disease.

The dual activating potential of peroxisome proliferator-activated receptors (PPAR) α and γ offers a promising way to address metabolic issues, neuroi...

Jul 15 2026 42458794
Personalized machine learning prediction of next-day migraine persistence using digital headache diary data.

OBJECTIVES/BACKGROUND: Migraine is a disabling neurological disorder with substantial interindividual variability. Predicting whether an ongoing migra...

Jul 15 2026 42458903
Amyloid-like nanofilm-decorated antifouling field effect transistor biosensor array for enhancing Alzheimer's disease diagnosis.

Alzheimer's disease (AD) is a common neurodegenerative disorder. Compared to the limited specificity of single-biomarker detection, the combined detec...

Jul 15 2026 42462634
Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI.

BACKGROUND: The Fazekas score is widely used to grade white matter hyperintensities (WMHs) in cerebral small vessel disease, yet the equivalent volume...

Jul 15 2026 42454405
Digital profiling of dysarthria in late- and early-onset Parkinson's disease.

BackgroundDigital speech analysis affords robust markers of Parkinson's disease (PD). However, most studies target late-onset PD (LOPD), neglecting ea...

Jul 15 2026 42455043
A comparative evaluation of brain MRI modalities, modality-specific measures, brain regions, and cognitive tests for brain age prediction.

Brain age estimation using machine learning has gained significant attention as a promising approach to assess cognitive health and aging. By analyzin...

Jul 15 2026 42455398
Ketogenic β-hydroxybutyrate-regulated β-hydroxybutyrylation of HSPE1 alleviates neuronal apoptosis in MPTP/MPP+ induced Parkinson's disease models.

Lysine β-hydroxybutyrylation (Kbhb) is an emerging post-translational modification regulated by β-hydroxybutyrate (BHB), a key metabolic intermediate ...

Jul 15 2026 42455758
Neuroinformed spectro-temporal-spatial attention with bi-hemispheric learning for EEG emotion recognition.

Accurate recognition of human emotions from electroencephalogram (EEG) signals is fundamental to affective computing, yet it remains challenging due t...

Jul 15 2026 42456726
Precision-Driven Management of Great Saphenous Varicose Veins: A Narrative Review.

OBJECTIVES: Great saphenous vein (GSV) incompetence is common, but numerous treatment options complicate patient-treatment matching. This narrative re...

Jul 15 2026 42456969
DST-GNN: A dynamic spatio-temporal graph neural network for motor imagery classification.

Electroencephalography (EEG)-based motor imagery classification plays an important role in brain-computer interface (BCI) systems. However, existing m...

Jul 15 2026 42457715
Cognitive structure and progression in Parkinson's disease: insights from a tablet-based assessment.

Cognitive impairment is an important constraint for PwPD with Parkinson's disease (PwPD). Digital assessments potentially provide more accessible meas...

Jul 15 2026 42457903
Neurophysiological EEG Characterization of Autism Spectrum Disorder Using DWT-Based Frequency Analysis With Selective Electrodes and Brain Segmentation: An Explainable AI-Driven Approach.

Autism Spectrum Disorder (ASD) diagnosis benefits from the technical analysis of neural oscillations. The objective identification of Autism Spectrum ...

Jul 15 2026 42417525
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