Obesity

Women in Translational Medicine: Tools to Break the Glass Ceiling.

Despite the recent movements for female equality and empowerment, few women occupy top positions in scientific decision-making. The challenges women face during their career may arise from societal biases and the current scientific culture. We discuss the effect of such biases at three different levels of the career and provide suggestions to tackle them. At the societal level, gender roles can cr...

Diabetes and Obesity Associated with Poor Food Environments in American Indian Communities: the Tribal Health and Resilience in Vulnerable Environments (THRIVE) Study.

BACKGROUND: American Indians (AIs) have significantly higher rates of diet-related chronic diseases than other racial/ethnic groups, and many live in environments with limited access to healthy food.

Exploring the interactions between serum free fatty acids and fecal microbiota in obesity through a machine learning algorithm.

Serum free fatty acids (FFA) are generally elevated in obesity. The gut microbiota is involved in the host energy metabolism through the regulation of...

Insulin resistance and adrenal incidentalomas: A bidirectional relationship.

An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological modality, independent of an endocrinological investigation. In ...

Disease comorbidity-guided drug repositioning: a case study in schizophrenia.

UNLABELLED: The key to any computational drug repositioning is the availability of relevant data in machine-understandable format. While large amount ...

Scalable Electronic Phenotyping For Studying Patient Comorbidities.

Over 75 million Americans have multiple concurrent chronic conditions and medical decision making for these patients is mostly based on retrospective ...

A reliable method for colorectal cancer prediction based on feature selection and support vector machine.

Colorectal cancer (CRC) is a common cancer responsible for approximately 600,000 deaths per year worldwide. Thus, it is very important to find the rel...

Machine learning based classification of cells into chronological stages using single-cell transcriptomics.

Age-associated deterioration of cellular physiology leads to pathological conditions. The ability to detect premature aging could provide a window for...

The Healthy Children, Strong Families 2 (HCSF2) Randomized Controlled Trial Improved Healthy Behaviors in American Indian Families with Young Children.

BACKGROUND: American Indian (AI) families experience a disproportionate risk of obesity due to a number of complex reasons, including poverty, histori...

Multiple Human-Behaviour Indicators for Predicting Lung Cancer Mortality with Support Vector Machine.

Lung cancer is still one of the most common causes of death around the world, while there is overwhelming evidence that the environment and lifestyle ...

Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency, and liver failure.

OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care ...

Adaptive Neural Control of a Kinematically Redundant Exoskeleton Robot Using Brain-Machine Interfaces.

In this paper, a closed-loop control has been developed for the exoskeleton robot system based on brain-machine interface (BMI). Adaptive controllers ...

Control of a Robot Arm Using Decoded Joint Angles from Electrocorticograms in Primate.

Electrocorticogram (ECoG) is a well-known recording method for the less invasive brain machine interface (BMI). Our previous studies have succeeded in...

Minimally invasive, robot-assisted procedure for kidney transplantation among morbidly obese: Positive outcomes at 5 years post-transplant.

The pre-transplant weight loss required of end-stage renal disease patients is often unachievable. Though robot-assisted procedures among extremely ob...

Obesity and chronic kidney disease progression-the role of a new adipocytokine: C1q/tumour necrosis factor-related protein-1.

BACKGROUND: Obesity is a risk factor for incident chronic kidney disease (CKD) in the general population. C1q/tumour necrosis factor-related protein 1...

Progress in the Development and Challenges for the Use of Artificial Kidneys and Wearable Dialysis Devices.

BACKGROUND: Renal transplantation is the treatment of choice for chronic kidney disease (CKD) patients, but the shortage of kidneys and the disabling ...

An Increased Level of Aryl Hydrocarbon Receptor in Patients with Pancreatic Cancer.

BACKGROUND Aryl-carbon receptor (AhR), a ligand-activated transcription factor, is best known for its ability to mediate the effects of environmental ...

Therapeutic Enoxaparin in the Morbidly Obese Patient: A Case Report and Review of the Literature.

Enoxaparin is a low molecular weight heparin commonly used in the treatment of venous thromboembolisms (VTEs); however, evidence on optimal empiric do...

Organization of the cancer network in SUS: evolution of the care model.

In the current context of epidemiological transition, demographic changes, changes in consumption and lifestyle habits, and pressure on care costs and...

Deep learning-based quantification of abdominal fat on magnetic resonance images.

Obesity is increasingly prevalent and associated with increased risk of developing type 2 diabetes, cardiovascular diseases, and cancer. Magnetic reso...