Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Fusion of Deep Transfer Learning and Radiomics in MRI-Based Prediction of Post-Surgical Recurrence in Soft Tissue Sarcoma.

Soft  tissue sarcomas (STS) are heterogeneous malignancies with high recurrence rates (33-39%) post-surgery, necessitating improved prognostic tools. This study proposes a fusion model integrating deep transfer learning and radiomics from MRI to predict postoperative STS recurrence. Axial T2-weighted fat-suppressed imaging (T2WI) of 803 STS patients from two institutions was retrospectively collec...

Sep 2 2025 40897833

Super-Resolution MR Spectroscopic Imaging via Diffusion Models for Tumor Metabolism Mapping.

High-resolution magnetic resonance spectroscopic imaging (MRSI) plays a crucial role in characterizing tumor metabolism and guiding clinical decisions for glioma patients. However, due to inherently low metabolite concentrations and signal-to-noise ratio (SNR) limitations, MRSI data are often acquired at low spatial resolution, hindering accurate visualization of tumor heterogeneity and margins. I...

Sep 2 2025 40897835
Identifying meaningful drug response biomarkers from public pharmacogenomic datasets with biologically informed interpretable neural networks.

With the advancements of next-generation sequencing, publicly available pharmacogenomic datasets from cancer cell lines provide a handle for developin...

Sep 2 2025 40914994
Multiview-cooperated graph neural network enables novel multi-omics cancer subtype classification.

Cancer presents a significant challenge in the field of public health due to its high incidence, mortality rate, and inherent heterogeneity. Integrati...

Sep 1 2025 40907459
Application of artificial intelligence in oral potentially malignant disorders: current opinions and future barriers.

Oral potentially malignant disorders (OPMDs) refer to oral mucosal disorders with an increased risk of malignancy, primarily oral squamous cell carcin...

Aug 30 2025 40885838
Novel risk calculator predicting long-term survival in pediatric versus adult patients diagnosed with spinal low-grade glioma: a nationwide analysis.

BACKGROUND CONTEXT: Spinal low-grade gliomas (SLGGs) are rare, slow-growing central nervous system tumors affecting both pediatric and adult populatio...

Aug 28 2025 40885265
Development and validation of AI-driven multi-omics language models for cancer genomics: A comprehensive review.

The pervasive challenges in cancer management, ranging from accurate early diagnosis to effective personalised therapies and precise patient stratific...

Aug 27 2025 40886665
Identification of uridine phosphatase 1 as a potential therapeutic target in gastric cancer by integrated bioinformatics analysis and experimental validation.

Gastric cancer remains a major global health challenge, and its early diagnosis and prognosis prediction pose significant challenges to the current cl...

Aug 26 2025 40855937
OCR: OmniNet-Fusion: A hybrid attention-based CNN-RNN model for multi-omics integration in precision cancer drug response prediction.

The growing complexity of cancer therapeutics challenges the use of state-of-the-art computational models for drug response prediction. Design and imp...

Aug 26 2025 40902256
Screening for Barrett Esophagus and Esophageal Adenocarcinoma: Approaches and Outcomes.

Barrett esophagus (BE) is the only known histological precursor to esophageal adenocarcinoma (EAC). The incidence of EAC has risen significantly over ...

Aug 25 2025 40874980
[Anna AI - a voluntary AI tool to complement psychosocial care in oncology].

Psychosocial support in oncology is gaining increasing importance in the comprehensive therapy and care of cancer patients, yet personal assistance re...

Aug 22 2025 41819064
Development and validation of a natural language processing system to assess quality of physician communication in prostate cancer consultations.

BACKGROUND: AUA guidelines for shared decision making (SDM) in prostate cancer recommend discussion of five content areas in consultations: (1) cancer...

Aug 21 2025 40841832
Spatial imaging features derived from SUVmax location in resectable NSCLC are associated with tumor aggressiveness.

PURPOSE: Accurate non-invasive prediction of histopathologic invasiveness and recurrence risk remains a clinical challenge in resectable non-small cel...

Aug 21 2025 40839309
Utilizing a combined approach of machine learning and structure-based drug design principles to identify potential hits targeting SphK1.

Sphingosine kinase (SphK1) is acrucial enzyme that aids in the processing of sphingolipids by adding a phosphate group to sphingosine, converting it i...

Aug 21 2025 40876399
Efficient lightweight CNN for automated classification of B-cell acute lymphoblastic leukemia.

B-cell acute lymphoblastic leukemia (B-ALL) is an aggressive hematological malignancy that primarily affects children but can also occur in adults, pr...

Aug 20 2025 40845691
LYnet: Computational identification of tumor T cell antigens using convolutional and recurrent neural networks.

BACKGROUND: Immunotherapy represents a paradigm shift in oncology, offering advantages in efficacy and specificity over traditional therapies. Key to ...

Aug 19 2025 40876398
Artificial Intelligence for Quantifying Endoscopic Mucosal Ulceration in Crohn's Disease.

BACKGROUND & AIMS: Endoscopic scoring of Crohn's disease (CD) is challenging, as mucosal disease is patchy with highly variable morphology, size, and ...

Aug 18 2025 40835044
When Health Behavior Meets Technology: Artificial Neural Network-Based Prediction of Breast Self-Examination Intentions Among Filipino Female College Students.

Early detection of breast cancer is crucial, particularly in low-resource settings. Emerging technologies like artificial neural networks (ANNs) offer...

Aug 16 2025 40817992
Evaluation of ChatGPT accuracy and reliability in answering questions about exercise recommendations for breast cancer survivors.

OBJECTIVE: To assess the accuracy and reliability of an artificial intelligence (AI) chatbot (ChatGPT) in providing answers about exercise recommendat...

Aug 16 2025 41270301
Automating the Referral of Bone Metastases Patients With and Without the Use of Large Language Models.

BACKGROUND AND OBJECTIVES: Bone metastases, affecting more than 4.8% of patients with cancer annually, and particularly spinal metastases require urge...

Aug 15 2025 40823772
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