Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 4461-4480 of 18,739 articles

Deep learning-based contour propagation in magnetic resonance imaging-guided radiotherapy of lung cancer patients.

Fast and accurate organ-at-risk (OAR) and gross tumor volume (GTV) contour propagation methods are needed to improve the efficiency of magnetic resonance (MR) imaging-guided radiotherapy. We trained deformable image registration networks to accurately propagate contours from planning to fraction MR images. Approach: Data from 140 stage 1-2 lung cancer patients treated at a 0.35T MR-Linac were ...

Jun 26 2025 40570891

A machine learning model integrating clinical-radiomics-deep learning features accurately predicts postoperative recurrence and metastasis of primary gastrointestinal stromal tumors.

OBJECTIVES: Post-surgical prediction of recurrence or metastasis for primary gastrointestinal stromal tumors (GISTs) remains challenging. We aim to develop individualized clinical follow-up strategies for primary GIST patients, such as shortening follow-up time or extending drug administration based on the clinical deep learning radiomics model (CDLRM).

Jun 26 2025 40571854
Multi-site validation of an interpretable model to analyze breast masses.

An external validation of IAIA-BL-a deep-learning based, inherently interpretable breast lesion malignancy prediction model-was performed on two patie...

Jun 26 2025 40569906
Advancing Design Strategy of PROTACs for Cancer Therapy.

Proteolysis targeting chimeras (PROTACs) have emerged as a groundbreaking class of anticancer therapeutics. These bifunctional molecules harness the e...

Jun 25 2025 40567248
The impact of intensity discretisation and filtration on the performance of the radiomic and machine learning models in brain metastasis patients treated with gamma knife radiosurgery.

INTRODUCTION: Image preprocessing is crucial for optimizing radiomics feature extraction, however, inconsistencies in the implementation process and a...

Jun 25 2025 40570507
Two-stage ensemble learning framework for automated classification of keratoconus severity.

BACKGROUND AND OBJECTIVE: Accurate staging of keratoconus (KC) is crucial for timely intervention and improving patient quality of life. Unlike prior ...

Jun 25 2025 40570767
Diagnostic Performance of Radiomics for Differentiating Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma: A Systematic Review and Meta-analysis.

BACKGROUND: Differentiating intrahepatic cholangiocarcinoma (ICC) from hepatocellular carcinoma (HCC) is essential for selecting the most effective tr...

Jun 25 2025 40571544
Intra-tumor microbiome-based tumor survival indices predict immune interaction and drug sensitivity on pan-cancer scale.

UNLABELLED: Growing research evidence indicates a substantial influence of the intra-tumor microbiome on tumor outcome. However, there is currently no...

Jun 25 2025 40558028
Exploring the complex interplay between oral infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs.

() is an oral commensal bacterium that can become pathogenic and is associated with periodontitis, adverse pregnancy outcomes, and colorectal cancer ...

Jun 25 2025 40558049
High-performance Open-source AI for Breast Cancer Detection and Localization in MRI.

Purpose To develop and evaluate an open-source deep learning model for detection and localization of breast cancer on MRI. Materials and Methods In t...

Jun 25 2025 40560044
Mapping breast cancer research on monoclonal antibodies: a data-driven approach using VOSviewer, Bibliometrix, and CiteSpace.

Monoclonal Antibodies and Breast Cancer Research (MABCR) has progressed substantially, particularly in the areas of HER2-positive and triple-negative ...

Jun 25 2025 40560396
Artificial Intelligence-Powered Spatial Analysis of Immune Phenotypes in Resected Pancreatic Cancer.

IMPORTANCE: Although tumor-infiltrating lymphocytes (TILs) have been implicated as prognostic biomarkers across various malignancies, the clinical app...

Jun 25 2025 40560550
Risk Classification of Low-Resolution Whole-Slide Thumbnail Images by Multi-dimensional Feature Reconstruction with Multi-task Deep Learning Network Helps Prioritize Pathology Case Registration.

Contemporary surgical pathology workflows often prioritize slide examination based on case registry order rather than patient risk level. As a result,...

Jun 25 2025 40563041
Impact of proton versus photon radiotherapy on overall survival in the management of spinal chordoma and mortality risk prediction: a nationwide analysis.

PURPOSE: This study aims to provide a national-level insight into the optimal management of spinal chordoma, a type of rare and complicated malignancy...

Jun 25 2025 40563064
Integrated transcriptome analysis and combinatorial machine learning to construct a homeostatic model of acetylation for ccRCC and validate the key gene GCNT4.

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant tumors of the urinary system. Protein acetylation plays a key ...

Jun 25 2025 40563096
A hybrid multi-instance learning-based identification of gastric adenocarcinoma differentiation on whole-slide images.

OBJECTIVE: To investigate the potential of a hybrid multi-instance learning model (TGMIL) combining Transformer and graph attention networks for class...

Jun 25 2025 40563099
Machine learning-driven national analysis for predicting adverse outcomes in intramedullary spinal cord tumor surgery.

UNLABELLED: Spinal tumors represent 15% of all central nervous system malignancies, with intramedullary spinal cord tumors (IMSCTs) being rare. Predom...

Jun 25 2025 40555868
[Current situation and development trends of minimally invasive surgical procedures in the treatment of pancreatic tumors].

With the rapid development of modern medical technology,minimally invasive surgical procedures are playing an increasingly important role in the field...

Jun 25 2025 40556394
Deep learning algorithms from histopathological images stratify molecular subtypes for leiomyosarcoma: a proof-and-concept diagnostic study.

BACKGROUND: The leiomyosarocma (LMS) is the most common soft tissue sarcoma, and its molecular subtypes were identified with therapeutic sensitivity a...

Jun 25 2025 40557542
Neural network prediction model based on Levy flight and natural biomimetic technology for its application in cancer prediction.

Precise forecasting of cancer outcomes is essential for medical professionals to assess the well-being of patients and develop customized therapeutic ...

Jun 25 2025 40561113
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