Ophthalmology

Latest AI and machine learning research in ophthalmology for healthcare professionals.

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Domain-Shift AI Technology for Vendor-Agnostic Multiple Macular Disease Detection From 3D OCT Scans.

IMPORTANCE: A deep learning (DL) model capable of analyzing optical coherence tomography (OCT) 3-dimensional (3D) scans from various vendors is essential for robust disease detection. OBJECTIVE: To develop a vendor-agnostic model for multidisease classification using 3D scans from different vendors. DESIGN, SETTING, AND PARTICIPANTS: This multicenter retrospective cohort study included OCT scans f...

Feb 26 2026 41746616

Patient perceptions of artificial intelligence in ophthalmology: a cross-sectional survey study.

BACKGROUND/AIMS: Patients have largely been excluded from discussions on the use of their health data in developing medical artificial intelligence (AI), despite being directly affected by its integration into care. This study assessed ophthalmology patients' perspectives on AI to inform patient-aligned development and implementation. METHODS: We conducted a cross-sectional survey across ophthalmo...

Feb 26 2026 41748311
Ryanodine receptor 2 mutations in catecholaminergic polymorphic ventricular tachycardia: From molecular mechanisms to precision medicine.

Catecholaminergic polymorphic ventricular tachycardia is a classic example of the successful transfer of genetic cardiology from gene discovery to imp...

Feb 26 2026 41694040
Flicker-Suppressed Neuromorphic Unit for Dynamic Vision Processing.

Inspired by the dynamic visual perception of flying insects, rapid collision warning systems are crucial for advancing autonomous driving and machine ...

Feb 25 2026 41738434
Photophysics-Guided Upconversion Nanosystems for Sensing.

ConspectusPhoton upconversion, which converts low-energy near-infrared light into higher-energy emission, has emerged as a powerful tool at the inters...

Feb 25 2026 41739086
Artificial intelligence and machine learning for plasmonic and surface-enhanced sensing.

Plasmonic sensing is a vibrant field where the optical properties of surface plasmons are exploited to create analytical sensors for biomedical, envir...

Feb 25 2026 41739092
Teleophthalmology Programs in Underserved Communities in the United States: A Narrative Review.

Underserved communities in the United States continue to face substantial barriers to accessing eye care, leading to preventable vision loss. This rev...

Feb 25 2026 41740052
Anticipating Moral and Economic Considerations, Opportunities, and Potential Frictions for AI in Medical Imaging: Multistakeholder Cocreation Study.

BACKGROUND: Artificial intelligence (AI) promises to significantly impact daily radiology practices. Numerous studies have already been conducted that...

Feb 25 2026 41740116
Flexible Coupling of Synaptic and Intrinsic Plasticity in a Cerebellar Circuit.

It is increasingly recognized that learning and memory depend, not only on changes in synaptic strength, but also on experience-dependent modification...

Feb 25 2026 41741208
AI-assisted analysis of early fluid dynamics following aflibercept 8 mg in treatment-naïve neovascular AMD.

PURPOSE: To evaluate early morphological changes following intravitreal aflibercept 8 mg in treatment-naïve neovascular age-related macular degenerati...

Feb 25 2026 41741701
Considering the missing science of retraining and maintenance in medical artificial intelligence, using ophthalmology as an exemplar.

Considerations around model retraining are standard practice in industry and non-healthcare sectors; however, this is much less well explored in medic...

Feb 25 2026 41741715
Deep Learning-Based Prediction of Visual Field Mean Deviation from Numeric OCT Data in Glaucoma.

The purpose is to evaluate whether numeric optical coherence tomography (OCT) data can predict Humphrey Visual Field Analyzer (HFA) 30-2 mean deviatio...

Feb 25 2026 41741850
Advancing the forward-forward algorithm towards high-performance deep local learning.

The Forward-Forward (FF) algorithm was recently proposed as a local learning method to address the limitations of backpropagation (BP), offering a mem...

Feb 24 2026 41780277
Deep Learning-Based Diagnostic Model for Ocular Surface Neoplastic Diseases.

PURPOSE: To develop a deep learning (DL) model for diagnosing ocular surface tumors and evaluating its diagnostic performance. SETTING: Development of...

Feb 24 2026 41748055
Macula Spatial Patterns and Their Association With Central Visual Field Progression in Glaucoma Using Artificial Intelligence.

PRECIS: Artificial intelligence-derived macular thinning patterns were associated with central visual field progression in glaucoma and outperformed g...

Feb 24 2026 41875177
Integrative transcriptomic and machine learning analysis identifies CDH17 and HOXC13 as robust candidate prognostic biomarkers in uveal melanoma.

BACKGROUND: Uveal melanoma (UM), the most common form of ocular melanoma, represents poor prognosis, with approximately 50% of patients developing met...

Feb 24 2026 41740484
Apps for people with vision impairment: an international review of practitioner suggestions and app availability.

CLINICAL RELEVANCE: Assistive smartphone apps play an integral role in supporting people with vision impairment (VI). Low vision rehabilitation (LVR) ...

Feb 24 2026 41734772
Contextual anatomy-guided deep learning for accurate fovea segmentation in diabetic retinopathy fundus images.

Accurate fovea segmentation in fundus images is a critical step in diabetic retinopathy screening; however, it remains a challenging task due to the i...

Feb 24 2026 41735453
Advancements of ultrasound modalities and their clinical potential in ophthalmology.

Ultrasound imaging has played an important role in ophthalmic diagnostics due to its real-time capability, safety, and cost-effectiveness. In recent y...

Feb 24 2026 41747839
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