Ophthalmology

Latest AI and machine learning research in ophthalmology for healthcare professionals.

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Emerging innovations in ophthalmic drug delivery for diabetic retinopathy: a translational perspective.

Diabetic retinopathy (DR) is a progressive microvascular complication of diabetes and a leading cause of vision impairment worldwide. Despite advancements in pharmacotherapy, challenges such as poor intraocular bioavailability, rapid drug clearance, and the restrictive blood-retinal barrier hinder effective treatment. Recent innovations in ophthalmic drug delivery systems offer promising solutions...

Jul 20 2025 40685494

Diagnosing pathologic myopia by identifying morphologic patterns using ultra widefield images with deep learning.

Pathologic myopia is a leading cause of visual impairment and blindness. While deep learning-based approaches aid in recognizing pathologic myopia using color fundus photography, they often rely on implicit patterns that lack clinical interpretability. This study aims to diagnose pathologic myopia by identifying clinically significant morphologic patterns, specifically posterior staphyloma and myo...

Jul 13 2025 40653573
Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus.

An underlying association between primary open-angle glaucoma (POAG) and COVID-19 has been hypothesized, but the causal link and shared mechanisms rem...

Jul 12 2025 40652070
Prediction of Cerebrospinal Fluid (CSF) Pressure with Generative Adversarial Network Synthetic Plasma-CSF Biomarker Pairing.

Non-invasive intracranial pressure (ICP) monitoring can help clinicians safely and efficiently monitor spaceflight-associated neuro-ocular syndrome (S...

Jul 10 2025 40637963
Ensemble machine learning prediction model for clinical refraction using partial interferometry measurements in childhood.

PURPOSE: To develop an ensemble machine learning prediction model for clinical refraction in childhood using partial interferometry measurements.

Jul 10 2025 40638665
Single-cell spatial transcriptomics reveals immunotherapy-driven bone marrow niche remodeling in AML.

Given the graft-versus-leukemia effect observed with allogeneic hematopoietic stem cell transplantation in refractory or relapsed acute myeloid leukem...

Jul 9 2025 40632867
Performance of ChatGPT on optometry and vision science exam questions.

The rapid proliferation of Large Language Models (LLM) tools, such as ChatGPT developed by OpenAI, presents both a challenge and an opportunity for ed...

Jul 9 2025 40631633
Artificial Intelligence-Enabled Facial Privacy Protection for Ocular Diagnosis: Development and Validation Study.

BACKGROUND: Facial biometric data, while valuable for clinical applications, poses substantial privacy and security risks.

Jul 9 2025 40632819
Diabetic retinopathy detection using adaptive deep convolutional neural networks on fundus images.

Diabetic retinopathy (DR) is an age-related macular degeneration eye disease problem that causes pathological changes in the retinal neural and vascul...

Jul 9 2025 40634513
Deep learning for predicting myopia severity classification method.

BACKGROUND: Myopia is a major cause of vision impairment. To improve the efficiency of myopia screening, this paper proposes a deep learning model, X-...

Jul 9 2025 40634962
Making data markets: Assetization, valuation, and proxy work in a digital health start-up.

Digital data are increasingly framed as essential resources in health and medicine, implicating diverse actors who work to transform them into differe...

Jul 9 2025 40635358
Diverse prey capture strategies in teleost larvae.

Animal behavior is adapted to the sensory environment in which it evolved, while also being constrained by physical limits, evolutionary history, and ...

Jul 8 2025 40624921
Unveiling aging heterogeneities in human dermal fibroblasts via nanosensor chemical cytometry.

Aging heterogeneity in tissue-regenerative cells leads to variable therapeutic outcomes, complicating quality control and clinical predictability. Con...

Jul 8 2025 40628739
Machine learning-assisted early detection of keratoconus: a comparative analysis of corneal topography and biomechanical data.

Keratoconus is a progressive eye disease characterized by the thinning and bulging of the cornea, leading to visual impairment. Early and accurate dia...

Jul 8 2025 40629001
Graph-based vision transformer with sparsity for training on small datasets from scratch.

Vision Transformers (ViTs) have achieved impressive results in large-scale image classification. However, when training from scratch on small datasets...

Jul 8 2025 40629056
Reviving the Past, Moving on to the Present, and Planning for the Future of Craniofacial Malformations.

The malformed newborn with craniofacial anomalies was variously regarded in different civilizations. Some populations considered it a symbol of the pr...

Jul 7 2025 40623138
Automated fluid monitoring to optimize the follow-up of neovascular age-related macular degeneration patients in the Brazilian population.

OBJECTIVES: To investigate the efficacy of an artificial intelligence (AI)-based fluid monitoring tool in optimizing the monitoring of neovascular age...

Jul 6 2025 40619442
Diabetic retinopathy in rural communities: a review of barriers to access of care and potential solutions.

INTRODUCTION: Diabetic retinopathy (DR) is a leading cause of vision loss. With an estimated 38.4 million Americans diagnosed with DM, the disease exe...

Jul 4 2025 40613644
Computational modelling of aggressive B-cell lymphoma.

Decades of research into the molecular signalling determinants of B cell fates, and recent progress in characterising the genetic drivers of lymphoma,...

Jul 4 2025 40613779
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