Orthopedics

Intravenous Infusion of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats.

INTRODUCTION: Intravenous preload (delivered before cavernous nerve [CN] injury) of bone marrow-derived mesenchymal stem cells (MSCs) can prevent or decrease postoperative erectile dysfunction (J Sex Med 2015;12:1713-1721). In the present study, the potential therapeutic effects of intravenously administered MSCs on postoperative erectile dysfunction were evaluated in a rat model of CN injury.

Human Wharton's Jelly-Derived Stem Cells Display a Distinct Immunomodulatory and Proregenerative Transcriptional Signature Compared to Bone Marrow-Derived Stem Cells.

Mesenchymal stromal cells (MSCs) are multipotent stem cells with immunosuppressive and trophic support functions. While MSCs from different sources frequently display a similar appearance in culture, they often show differences in their surface marker and gene expression profiles. Although bone marrow is considered the "gold standard" tissue to isolate classical MSCs (BM-MSC), MSC-like cells are c...

Intra-articular collagenase injection increases range of motion in a rat knee flexion contracture model.

OBJECTIVES: A knee joint contracture, a loss in passive range of motion (ROM), can be caused by prolonged immobility. In a rat knee immobilization fle...

Communication with Orthopedic Trauma Patients via an Automated Mobile Phone Messaging Robot.

BACKGROUND: Communication with orthopedic trauma patients is traditionally problematic with low response rates (RRs). The purpose of this investigatio...

Reduced methicillin-resistant Staphylococcus aureus biofilm formation in bone cavities by photodynamic therapy.

UNLABELLED: Photodynamic Therapy (PDT) is a promising alternative for the treatment of infectious bone lesions in the oral cavity. The objective of th...

Leptin Stimulates Prolactin mRNA Expression in the Goldfish Pituitary through a Combination of the PI3K/Akt/mTOR, MKK/pMAPK and MEK/ERK Signalling Pathways.

Leptin actions at the pituitary level have been extensively investigated in mammalian species, but remain insufficiently characterized in lower verteb...

A randomized comparison between interscalene and combined infraclavicular-suprascapular blocks for arthroscopic shoulder surgery.

BACKGROUND: This randomized trial aimed to evaluate combined infraclavicular-suprascapular blocks (ICB-SSBs) as a diaphragm-sparing alternative to int...

Design, characterisation and evaluation of a soft robotic sock device on healthy subjects for assisted ankle rehabilitation.

Motor impairment is one of the common neurological conditions suffered by stroke patients, where this chronic immobility together with the absence of ...

Classification of optic disc shape in glaucoma using machine learning based on quantified ocular parameters.

PURPOSE: This study aimed to develop a machine learning-based algorithm for objective classification of the optic disc in patients with open-angle gla...

Topical Tranexamic Acid Reduces Blood Loss in Minimally Invasive Total Knee Arthroplasty Receiving Rivaroxaban.

BACKGROUND: It is unclear whether topical (intra-articular) or intravenous TXA reduces blood loss in minimally invasive TKA patients receiving a direc...

Artificial intelligence in fracture detection: transfer learning from deep convolutional neural networks.

AIM: To identify the extent to which transfer learning from deep convolutional neural networks (CNNs), pre-trained on non-medical images, can be used ...

Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.

Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properti...

In vitro activity of Nigella sativa against antibiotic resistant Salmonella enterica.

Salmonellosis is a major food-borne disease worldwide and antimicrobial resistance in Salmonella is a public health problem. Phytochemicals are altern...

Comparison of the Bone Harvesting Capacity of an Intraoral Bone Harvesting Device and Three Different Implant Drills.

The aim of the present study was to compare bone-collecting capacity of bone harvesting device and minimally irrigated low-speed drilling using three ...

White blood cell differential count of maturation stages in bone marrow smear using dual-stage convolutional neural networks.

The white blood cell differential count of the bone marrow provides information concerning the distribution of immature and mature cells within matura...

Results of Posterior Vertebral Column Resection: Surgical Modification of Suk Technique.

STUDY DESIGN: Consecutive, retrospective review.

A Novel Adaptive Deformable Model for Automated Optic Disc and Cup Segmentation to Aid Glaucoma Diagnosis.

This paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic...

Thoracolumbar Vertebral Injuries with Neurological Deficit Treated with Posterior Decompression, Short Segment Pedicle Screw Fixation, and Interlaminar Fusion.

STUDY DESIGN: Prospective clinical study.

Automatic spinal cord localization, robust to MRI contrasts using global curve optimization.

During the last two decades, MRI has been increasingly used for providing valuable quantitative information about spinal cord morphometry, such as qua...

Effectiveness of robot-assisted training added to conventional rehabilitation in patients with humeral fracture early after surgical treatment: protocol of a randomised, controlled, multicentre trial.

BACKGROUND: The incidence of proximal humeral fractures increases with age. The functional recovery of the upper arm after such fractures is slow, and...