Orthopedics

Design, synthesis, antibacterial evaluation and molecular docking studies of some new quinoxaline derivatives targeting dihyropteroate synthase enzyme.

Development of new antimicrobial agents is a good solution to overcome drug-resistance problems. From this perspective, new quinoxaline derivatives bearing various bioactive heterocyclic moieties (thiadiazoles, oxadiazoles, pyrazoles and thiazoles) were designed and synthesized. The newly synthesized compounds were evaluated for their in vitro antibacterial activity against nine bacterial human pa...

Joint Hand Detection and Rotation Estimation Using CNN.

Hand detection is essential for many hand related tasks, e.g., recovering hand pose and understanding gesture. However, hand detection in uncontrolled environments is challenging due to the flexibility of wrist joint and cluttered background. We propose a convolutional neural network (CNN), which formulates in-plane rotation explicitly to solve hand detection and rotation estimation jointly. Our n...

Proprioceptive assessment in clinical settings: Evaluation of joint position sense in upper limb post-stroke using a robotic manipulator.

Proprioception is a critical component for motor functions and directly affects motor learning after neurological injuries. Conventional methods for i...

Feasibility of Bone Perfusion Evaluation in Cadavers Using Indocyanine Green Fluorescence Angiography.

Bone perfusion evaluation methods in cadaver studies have yet to be established. The aim of this report was to introduce and validate the feasibility ...

Artificial neural networks to predict future bone mineral density and bone loss rate in Japanese postmenopausal women.

OBJECTIVE: Predictions of the future bone mineral density and bone loss rate are important to tailor medicine for women with osteoporosis, because of ...

Nail Sarcoidosis Presenting with Longitudinal Erythronychia.

A 37-year-old woman presented with progressive longitudinal erythronychia and onychorrhexis of the toenails. She had a history of sarcoidosis of the l...

A Machine Learning Ensemble Classifier for Early Prediction of Diabetic Retinopathy.

The main complication of diabetes is Diabetic retinopathy (DR), retinal vascular disease and it leads to the blindness. Regular screening for early DR...

Synthesis and characterization of ZnO phytonanocomposite using L. (Loganiaceae) and antimicrobial activity against multidrug-resistant bacterial strains from diabetic foot ulcer.

Nanobiotechnology has been emerged as an efficient technology for the development of antimicrobial nanoparticles through an eco-friendly approach. In ...

Performance of a Deep-Learning Neural Network Model in Assessing Skeletal Maturity on Pediatric Hand Radiographs.

Purpose To compare the performance of a deep-learning bone age assessment model based on hand radiographs with that of expert radiologists and that of...

Ultrasound-assisted extraction of antimicrobial compounds from Thymus daenensis and Silybum marianum: Antimicrobial activity with and without the presence of natural silver nanoparticles.

The present study is devoted to prepare a new antibacterial and antifungal agent based on in situ-synthesized silver nanoparticles at room temperature...

Design and Computational Modeling of a Modular, Compliant Robotic Assembly for Human Lumbar Unit and Spinal Cord Assistance.

Wearable soft robotic systems are enabling safer human-robot interaction and are proving to be instrumental for biomedical rehabilitation. In this man...

Zero-Echo-Time and Dixon Deep Pseudo-CT (ZeDD CT): Direct Generation of Pseudo-CT Images for Pelvic PET/MRI Attenuation Correction Using Deep Convolutional Neural Networks with Multiparametric MRI.

Accurate quantification of uptake on PET images depends on accurate attenuation correction in reconstruction. Current MR-based attenuation correction ...

Interacting With Robots to Investigate the Bases of Social Interaction.

Humans show a great natural ability at interacting with each other. Such efficiency in joint actions depends on a synergy between planned collaboratio...

Postoperative Myocardial Injury and Inflammation Is Not Blunted by a Trial of Atorvastatin in Orthopedic Surgery Patients.

BACKGROUND: Orthopedic patients are at risk for adverse postoperative cardiovascular outcomes.

Classification of the trabecular bone structure of osteoporotic patients using machine vision.

Osteoporosis is a common bone disease which often leads to fractures. Clinically, the major challenge for the automatic diagnosis of osteoporosis is t...

Design of a Lightweight Soft Robotic Arm Using Pneumatic Artificial Muscles and Inflatable Sleeves.

As robots begin to interact with humans and operate in human environments, safety becomes a major concern. Conventional robots, although reliable and ...

A Biologically Inspired, Functionally Graded End Effector for Soft Robotics Applications.

Soft robotic actuators offer many advantages over their rigid counterparts, but they often are unable to apply highly localized point loads. In contra...

Escape and surveillance asymmetries in locusts exposed to a Guinea fowl-mimicking robot predator.

Escape and surveillance responses to predators are lateralized in several vertebrate species. However, little is known on the laterality of escapes an...

A new hand-eye calibration approach for fracture reduction robot.

OBJECTIVE: The hand-eye calibration is used to determine the transformation between the end-effector and the camera marker of the robot. But the robot...

Robust Alternating Low-Rank Representation by joint L- and L-norm minimization.

We propose a robust Alternating Low-Rank Representation (ALRR) model formed by an alternating forward-backward representation process. For forward rep...