Orthopedics

Latest AI and machine learning research in orthopedics for healthcare professionals.

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Closed Loop Computer-based Artificial Intelligence Model "Maverik" to Help Diagnose and Differential Diagnoses of Childhood Onset Chronic Nonbacterial Osteomyelitis: Pilot Study.

BACKGROUND: Childhood-onset chronic nonbacterial osteomyelitis (CNO) is an inflammatory bone disease that has become better defined in the last 2 decades and is frequently encountered in pediatric rheumatology. As the disease is still not well known and is often confused with malignancy and growth pains, it can easily be missed in clinical practice. We aimed to develop and evaluate a computer-aide...

Dec 26 2025 41451463

Machine Learning Photodynamics Unveils a Controlled H2 Loss Channel in the Methaniminium Cation.

The methaniminium cation, CH2NH2+, plays an important role in Titan's N2-CH4 atmospheric chemistry. As the simplest protonated Schiff base (PSB), it also serves as a model for studying the nonadiabatic dynamics of the retinal PSB, the chromophore central to vertebrate vision. While previous studies have established CN bond cleavage and photoisomerization as the primary pathways in the photochemist...

Dec 26 2025 41452758
Machine Learning-Based Prediction Model for Alveolar Bone Defect Risk Following Orthodontic Treatment.

OBJECTIVES: Alveolar bone defects, such as fenestration and dehiscence, induced by orthodontic treatment represent significant complications that can ...

Dec 25 2025 41445473
Recent Advances in Musculoskeletal Radiology: Bridging Innovation and Clinical Application.

Recent advances in musculoskeletal (MSK) radiology have markedly improved diagnostic accuracy through innovations in MRI, CT, and artificial intellige...

Dec 25 2025 41443887
Artificial intelligence-assisted detection of soft tissue calcifications and ossifications in CBCT.

OBJECTIVES: This study aimed to integrate soft tissue calcifications and ossifications (STCO) detected on cone beam computed tomography (CBCT) into an...

Dec 24 2025 41539873
Prediction of independent ambulation at hospital discharge in patients with proximal femoral fractures based on preoperative clinical information: A retrospective study using extreme gradient boosting and SHapley additive explanations.

BACKGROUND: Independent ambulation at hospital discharge is a critical determinant of discharge destination and caregiving burden in older adults with...

Dec 24 2025 41478088
Are social robots more interesting than humans? Quantitative assessment of Joint Attention in autistic and typically developing children.

INTRODUCTION: Autism Spectrum Disorder (ASD) is characterized by deficits in social interaction and communication, including joint attention (JA) impa...

Dec 24 2025 41499901
SPP1-CD44 signaling contributes to the mechanisms and therapeutic implications in intervertebral disc degeneration.

BACKGROUND: Intervertebral disc degeneration (IVDD) is a major pathological cause of chronic back pain and reduced mobility. Among emerging molecular ...

Dec 24 2025 41475272
Ensemble machine learning for early mortality risk stratification in septic orthopedic trauma: an international cohort study.

BACKGROUND: Sepsis represents a life-threatening complication in severe orthopedic trauma, significantly increasing short-term mortality risk. Despite...

Dec 23 2025 41478161
An Unsupervised Learning Approach for Multimodal Low Back Pain Stratification.

STUDY DESIGN: Cross-sectional study. OBJECTIVE: This study proposes a novel stratification framework for individuals with low back pain (LBP). The met...

Dec 22 2025 41384355
Deep learning-based micro-CT grayscale analysis for early detection and staging of osteoporosis in rats.

BACKGROUND: Rat models are widely used in preclinical osteoporosis research to study disease mechanisms and evaluate therapies. Current Micro-CT studi...

Dec 21 2025 41435999
Identification of alkaline phosphatase as a putative biomarker of anti-NGF treatment-associated arthropathies: Machine learning-assisted analyses of clinical trial data.

OBJECTIVE: Nerve growth factor (NGF) inhibitors have been shown to provide pain relief in patients with osteoarthritis but are associated with adjudic...

Dec 18 2025 41540988
Time-resolved prediction of dental implant biomechanics through integration of finite element analysis, osseointegration dynamics, and deep learning.

BACKGROUND: Dental implant longevity depends on the complex interaction between mechanical stability and biological osseointegration. While finite ele...

Dec 16 2025 41411948
A multi-branch ConvNeXt-MaxViT fusion transformer model for radiographic knee osteoarthritis severity assessment with Grad-CAM++ explainability.

CONTEXT: Knee Osteoarthritis (KOA) is a progressive degenerative joint disorder and a major cause of disability worldwide. Radiographic grading using ...

Dec 16 2025 41541300
Development and Validation of an Automated Pipeline for the Detection of Monteggia Fracture Dislocations in Pediatric Radiographs.

BACKGROUND: Monteggia fractures are a complex elbow injury that can be missed in up to 50% of pediatric elbow injuries during initial radiographic ass...

Dec 15 2025 41395634
Evaluating an Artificial Intelligence software for opportunistic low bone mineral density and osteoporosis screening: a validation study.

Despite the profound prevalence and fracture risk of osteoporosis, access to the gold standard DXA scans remains limited, especially in rural communit...

Dec 15 2025 41522664
Sustainable silk fibroin scaffolds for bone repair: assessing their osteogenic potential via AI-enhanced synchrotron imaging workflow.

Effective bone regeneration requires scaffolds capable of guiding and supporting new mineralized matrix formation. In this study, silk fibroin constru...

Dec 13 2025 41406651
Predicting skeletal age from HR-pQCT imaging.

INTRODUCTION: High-resolution peripheral quantitative computed tomography (HR-pQCT) provides detailed bone microarchitecture assessments, but the inte...

Dec 13 2025 41391644
Artificial intelligence in lower limb joint moment prediction during typically developed gait: A systematic review and multilevel random-effects meta-analysis.

OBJECTIVE: Artificial intelligence (AI) methods have been widely applied in gait analysis, yet quantitative comparisons across models and their input-...

Dec 13 2025 41412059
mModPoEs: Multimodal posture estimation and feedback-driven correction of load-bearing human movements using wearable sensors and computer vision.

OBJECTIVE: Improper spinal posture during activities of daily living such as seated posture, upright stance, and ambulation, particularly under load-b...

Dec 12 2025 41492323
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