Endocrinology

Osteoporosis

Latest AI and machine learning research in osteoporosis for healthcare professionals.

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Towards end-to-end LLM-based censoring-aware survival analysis

Objective: Survival analysis is central to medical prediction, yet large language models (LLMs) are ...

Characterization of menopause onset and associated disease risks using large-scale electronic health records

Menopause affects over one billion women worldwide, yet remains poorly characterized at scale. We ap...

A dataset of simultaneous two-photon calcium imaging and auditory discrimination behavior

The emerging field of artificial intelligence for neuroscience relies heavily on high-quality, stand...

A Deep Learning-Based Scoring Framework for Large-Scale Multi-Donor Cardiotoxicity Screening

Cardiotoxicity remains a major cause of drug attrition and post-market withdrawal, yet the vast majo...

Integrative Clinical-Molecular Modeling Identifies LRRN4CL as a Determinant of Structural and Functional Myocardial Improvement

Background: Mechanical ventricular unloading and systemic circulatory support with left ventricular ...

A DNA foundation model predicts osteoporosis risk genes without proximity bias

Targets supported by human genetic associations are more than twice as likely to progress from clini...

Consumption of Reinforcing Solutions Engages Dynamic Activityof the Prelimbic Cortical Outputs

The medial prefrontal cortex integrates information about salience and valence of stimuli, including...

Transformer-Based Multi-Region Segmentation and Radiomic Analysis of HR-pQCT Imaging for Osteoporosis Classification

Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA),...

Transformer-Based Multi-Region Segmentation and Radiomic Analysis of HR-pQCT Imaging

Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA),...

A human iPS cell line for ready-to-use human iAstrocytes that support human neurons

Human iPSC-derived neuronal networks are increasingly being employed in basic and applied research t...

AI-Guided CRISPR Screen Accelerates Discovery of New Drug Targets

Psoriasis affects over 125 million people worldwide, yet the mechanistic understanding of keratinocy...

A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomography

Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on EC...

Gender-Specific Osteoporosis Risk Prediction Using Longitudinal Clinical Data and Machine Learning

Osteoporosis is a silent yet debilitating disease that often remains undetected until fractures occu...

Trisomy 21 impairs synchronized activity and connectivity in developing human Down syndrome cortical excitatory neuron networks

Down syndrome (DS) is the most common genetic cause of intellectual disability, affecting one in 700...

Calmodulin controls spatial and temporal specificity of calcium-induced calcium release

Calcium dynamics controls learning and memory. Changes in calcium-induced calcium release (CICR), wh...

Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights

Body mass index (BMI), type 2 diabetes (T2D) and associated cardiometabolic features modify Alzheime...

Comp2Comp: Open-Source Software with FDA-Cleared Artificial Intelligence Algorithms for Computed Tomography Image Analysis

Artificial intelligence allows automatic extraction of imaging biomarkers from already-acquired radi...

Population-Scale Analysis of Frequency-Dependent Calcium Dynamics in Retinal Ganglion Cells Under Electric Field Stimulation

Electric field (EF) stimulation is an emerging neuromodulatory strategy for promoting the repair and...

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