Pain Management

Latest AI and machine learning research in pain management for healthcare professionals.

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Machine learning-based prediction model for paresthesia improvement after open carpal tunnel release: a preliminary study.

BACKGROUND: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the hand. While carpal tunnel release surgery generally provides good outcomes, some patients continue to experience persistent paresthesia postoperatively. This study aimed to develop a machine learning-based prediction model for paresthesia improvement following carpal tunnel surgery. METHODS: We retrospectively...

Apr 30 2026 42057064

A prospective multimethod investigation of cancer-related pain integrating clinical data and machine learning: results from the RUGGI Study.

BACKGROUND: Cancer-related pain is a multidimensional phenomenon, and key determinants of pain intensity remain unclear. The aim of this study was to identify the clinical determinants of cancer-related pain intensity using a convergent, multimethod analytical framework. METHODS: Prospective observational study of patients with cancer-related pain. Pain was assessed using a 0-10 numeric rating sca...

Apr 30 2026 42057124
Risk and protective factors in addictive behaviors: Integrating artificial intelligence and traditional analytical methods to assess social and psychological determinants.

PURPOSE OF REVIEW: Addictive behaviors, including both substance use disorders and behavioral addictions, arise from complex interactions among biolog...

Apr 30 2026 42059150
Attention-based Multimodal Spatiotemporal Enhanced Interaction Network For Major Depressive Disorder Detection.

Although deep learning models have shown promising results in detecting major depressive disorder (MDD), two main limitations remain: insufficient exp...

Apr 30 2026 42060425
Magnetic Resonance Neurography: Evolution, Technical Foundations, and Future Directions.

ABSTRACT: In the past 20 years, magnetic resonance neurography has evolved from an experimental technique into an essential diagnostic pillar for peri...

Apr 30 2026 42061306
Deep Learning-Based Identification of Surgical Candidacy for Cervical Spinal Cord Decompression.

BACKGROUND: Artificial intelligence has previously demonstrated the capability to interpret cervical spine imaging. The present study aims to identify...

Apr 30 2026 42061991
The complexity of pain in osteoarthritis.

Chronic pain is the hall-mark symptom of osteoarthritis (OA) and although several therapies are available, a sizeable number of patients do not gain a...

Apr 30 2026 42062510
End-to-End Image Compression With Segmentation Guided Dual Coding for Wind Turbines.

Transferring large volumes of high-resolution images during wind turbine inspections introduces a bottleneck in assessing and detecting severe defects...

Apr 29 2026 42055998
Multi-directional State Space Modeling for Deciphering Spatial Domains From Spatially Resolved Transcriptomics.

Spatially resolved transcriptomics (SRT) enables the investigation of tissue architecture by mapping gene expression within its spatial context. Howev...

Apr 29 2026 42056000
A cross-sectional protocol for experimental tongue high-density surface electromyography to detect and classify radiation-associated hypoglossal neuropathy.

BACKGROUND: Hypoglossal neuropathy is the most common lower cranial neuropathy detected as a delayed sequelae of Human Papillomavirus (HPV) -driven or...

Apr 29 2026 42054414
Functional evaluation in adult spinal deformity can be reduced to 3 key kinematic parameters that can sufficiently predict health-related quality of life outcomes: an observational prospective study.

BACKGROUND CONTEXT: Recently, functional evaluation using 3D gait analysis (3DGA) proved to predict health-related quality-of-life (HRQOL) scores bett...

Apr 28 2026 42061763
Pfirrmann Grading and Features of Internal Derangement Identified in Discs Studied By Lumbar Discography in Patients with Chronic Low Back Pain.

BACKGROUND AND PURPOSE: Lumbar disc degeneration Pfirrmann Grade (PfGr) is commonly used to evaluate clinical studies assessing patient outcomes or ev...

Apr 28 2026 41386986
Modulating empathy with tDCS: dissociable roles of rTPJ and lDLPFC.

BACKGROUND: Empathy relies on distinct but interacting processes for representing others' states and regulating self-oriented affect. Neuroimaging stu...

Apr 28 2026 42047109
Single-molecule localization and diffusivity microscopy reveals dynamic biomolecular organization in living cells.

Single-molecule tracking in living cells measures protein diffusivity but requires sparse imaging, limiting high-density mapping. Here we introduce si...

Apr 28 2026 42050111
Development and validation of the Lebanese Social Media Dependency Scale (LSMDS): A cross-sectional study among university students.

BACKGROUND: Social media use has become pervasive among university students worldwide, with growing evidence linking excessive use to negative psychol...

Apr 28 2026 42048327
Evaluation and enhancement of suspected opioid overdose definitions in emergency medical services data using machine learning with natural language processing.

BACKGROUND: Fatal and non-fatal drug overdoses have evolved into a critical public health crisis, with over a 50% increase in the rate of fatal drug o...

Apr 28 2026 42048330
Current and emerging therapies for knee osteoarthritis: From conventional approaches to machine learning and stem cell innovations.

Osteoarthritis is characterized by cartilage degradation and joint distortion. The most prevalent version of osteoarthritis, knee osteoarthritis (KOA)...

Apr 26 2026 42077270
Algometric assessment of sensitization and habituation as predictive markers for OnabotulinumtoxinA response in chronic migraine.

BACKGROUND: Chronic migraine is a debilitating disorder characterized by central sensitization and impaired habituation. Although OnabotulinumtoxinA (...

Apr 26 2026 42036814
Data-driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology.

Alzheimer's disease neuropathological changes (ADNC)-operationalized with semi-quantitative parameters-represent the consensus-based gold standard for...

Apr 26 2026 42035704
DCSwinLSTM for spatiotemporal meteorological drought forecasting.

Meteorological drought prediction is critical for early warning and climate-risk management; yet, modeling regional drought evolution across multi-tim...

Apr 25 2026 42181264
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