Pain Management

Latest AI and machine learning research in pain management for healthcare professionals.

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Identifying and predicting headache trajectories among those with acute post-traumatic headache.

OBJECTIVES/BACKGROUND: Post-traumatic headache (PTH) is a common symptom following mild traumatic brain injury (mTBI). Currently, there is no identified way to accurately predict if, when, and at what pace a person will have PTH improvement. In our prior studies, we focused on predicting headache improvement at 3 months post-mTBI. However, that approach may overlook individual differences in how h...

May 30 2025 40444600

Automatic detection of optic canal fractures and recognition and segmentation of anatomical structures in the orbital apex based on artificial intelligence.

BACKGROUND AND OBJECTIVES: Traumatic optic neuropathy (TON) caused by optic canal fractures (OCF) can result in severe visual impairment, even blindness. Timely and accurate diagnosis and treatment are crucial for preserving visual function. However, diagnosing OCF can be challenging for inexperienced clinicians due to atypical OCF changes in imaging studies and variability in optic canal anatomy....

May 30 2025 40519266
Identification of NLRP3 Inflammasome-associated Biomarkers by Integrated Bioinformatics Analysis in Neuropathic Pain.

Neuropathic pain (NP) is a chronic disease due to nerve injury, viral infections, etc. Inflammatory factors are a key part of its pathological mechani...

May 29 2025 40439855
Evaluation of machine learning and deep learning algorithms for fire prediction in Southeast Asia.

Vegetation fires are most common in Southeast Asian (SEA) countries, causing biodiversity loss, habitat destruction, and air pollution. Accurately pre...

May 29 2025 40442135
Hierarchical Information-guided robotic grasp detection.

With the advancement of deep learning, robotic grasping has seen widespread application in fields, becoming a critical component in enhancing automati...

May 29 2025 40442259
Pathogenic mechanism of the K141E mutation in HSPB8: Insights from smFRET and simulations.

Pathogenic mutations can have a large impact on the conformational ensemble of intrinsically disordered proteins, but revealing those effects and thei...

May 29 2025 40449653
The analgesic mechanism of electroacupuncture at the central level for neuropathic pain: a review of studies based on animal experiments.

This article analyzes the progress of animal experiments on the analgesic mechanism of electroacupuncture (EA) at the central level for neuropathic pa...

May 29 2025 40510205
Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States.

BACKGROUND: Juvenile idiopathic arthritis (JIA) is a prevalent chronic rheumatological condition in children, with reported prevalence ranging from 12...

May 29 2025 40510579
Operationalizing postmortem pathology-MRI association studies in Alzheimer's disease and related disorders with MRI-guided histology sampling.

Postmortem neuropathological examination, while the gold standard for diagnosing neurodegenerative diseases, often relies on limited regional sampling...

May 28 2025 40437594
Deep Learning Differentiates Papilledema, NAION, and Healthy Eyes with Unsegmented 3D OCT Volumes.

OBJECTIVE: Deep learning (DL) has been used to differentiate papilledema from healthy eyes and optic disc elevation on fundus photos. As we described ...

May 28 2025 40447246
ST-GTrans: Spatio-temporal graph transformer with road network semantic awareness for traffic flow prediction.

Accurate traffic prediction has significant implications for traffic optimization and management. However, few studies have thoroughly considered the ...

May 28 2025 40466347
Mechanisms and management of self-resolving lumbar disc herniation: bridging molecular pathways to non-surgical clinical success.

Spontaneous resorption of lumbar disk herniation (LDH) presents a promising avenue for the non-surgical management of herniated disks. Here we present...

May 27 2025 40426259
Development and validation of a quick screening tool for predicting neck pain patients benefiting from spinal manipulation: a machine learning study.

BACKGROUND: Neck pain (NP) ranks among the leading causes of years lived with disability worldwide. While spinal manipulation is a common physical the...

May 27 2025 40426265
Multilevel Inter-modal and Intra-modal Transformer network with domain adversarial learning for multimodal sleep staging.

Sleep staging identification is a fundamental task for the diagnosis of sleep disorders. With the development of biosensing technology and deep learni...

May 26 2025 40438089
Assessing ChatGPT responses to patient questions on epidural steroid injections: A comparative study of general vs specific queries.

BACKGROUND: Artificial intelligence (AI) is becoming more integrated into healthcare, with large language models (LLMs) like ChatGPT being widely used...

May 26 2025 40511324
EEG microstate analysis in trigeminal neuralgia: identifying potential biomarkers for enhanced diagnostic accuracy.

OBJECTIVE: This study investigated EEG microstate dynamics in trigeminal neuralgia (TN) patients to understand the central nervous system's contributi...

May 26 2025 40418510
The future of target-controlled infusion and new pharmacokinetic models.

PURPOSE OF REVIEW: To summarize recent developments in the understanding of the pharmacology of the hypnotic and opioid drugs, with relevance to targe...

May 26 2025 40421498
Identifying key risk factors for intentional self-harm, including suicide, among a cohort of people prescribed opioid agonist treatment: A predictive modelling study.

BACKGROUND AND AIMS: People with opioid use disorder are at increased risk of intentional self-harm and suicide. Although risk factors are well known,...

May 25 2025 40415419
Multimodal Explainable Artificial Intelligence for Prognostic Stratification of Glioblastoma Patients.

Glioblastoma is the most common and aggressive malignant adult tumor of the central nervous system, with a grim prognosis and heterogeneous morphologi...

May 24 2025 40419087
Developing and validating a machine learning model to predict chronic pain following total knee arthroplasty.

OBJECTIVE: This study aims to compare the performance of various machine learning algorithms in predicting chronic pain after total knee arthroplasty ...

May 21 2025 40403433
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