Pancreatic Diseases

Machine learning-based diagnosis and risk factor analysis of cardiocerebrovascular disease based on KNHANES.

The prevalence of cardiocerebrovascular disease (CVD) is continuously increasing, and it is the leading cause of human death. Since it is difficult for physicians to screen thousands of people, high-accuracy and interpretable methods need to be presented. We developed four machine learning-based CVD classifiers (i.e., multi-layer perceptron, support vector machine, random forest, and light gradien...

Factors associated with long-term survival in gemcitabine-concurrent proton radiotherapy for non-metastatic locally advanced pancreatic cancer: a single-center retrospective study.

BACKGROUND: Factors associated with long-term survival in gemcitabine-concurrent proton radiotherapy (GPT) for non-metastatic, locally advanced pancreatic cancer (LAPC) remain unclear. This study aimed to determine the factors associated with long-term survival in GPT for non-metastatic LAPC.

Machine Learning of Single Cell Transcriptomic Data From anti-PD-1 Responders and Non-responders Reveals Distinct Resistance Mechanisms in Skin Cancers and PDAC.

Immune checkpoint therapies such as PD-1 blockade have vastly improved the treatment of numerous cancers, including basal cell carcinoma (BCC). Howeve...

Sequential endoscopic and robot-assisted surgical solutions for a rare fungal spondylodiscitis, secondary lumbar spinal stenosis, and subsequent discal pseudocyst causing acute cauda equina syndrome: a case report.

BACKGROUND: Fungal spondylodiscitis is a rare infectious disease. The secondary lumbar spinal stenosis and postoperative discal pseudocyst were even r...

Development of a deep learning-based patient-specific target contour prediction model for markerless tumor positioning.

PURPOSE: For pancreatic cancer patients, image guided radiation therapy and real-time tumor tracking (RTTT) techniques can deliver radiation to the ta...

Disease-Specific Imaging Utilizing Support Vector Machine Classification of H-Scan Parameters: Assessment of Steatosis in a Rat Model.

In medical imaging, quantitative measurements have shown promise in identifying diseases by classifying normal versus pathological parameters from tis...

Analysis of Clinical Parameters, Drug Consumption and Use of Health Resources in a Southern European Population with Alcohol Abuse Disorder during COVID-19 Pandemic.

The disruption in healthcare attention to people with alcohol dependence, along with psychological decompensation as a consequence of lockdown derived...

Automatic quantitative evaluation of normal pancreas based on deep learning in a Chinese adult population.

OBJECTIVE: To develop a 3D U-Net-based model for the automatic segmentation of the pancreas using the diameters, volume, and density of normal pancrea...

The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models.

(AG) is an ancient medicinal plant that is mainly distributed and used in southwest China. It exerts therapeutic effects, such as antioxidant, anti-d...

Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints.

Plasma exosomes have shown great potential for liquid biopsy in clinical cancer diagnosis. Herein, we present an integrated strategy for isolating and...

Design of Optimal Deep Learning-Based Pancreatic Tumor and Nontumor Classification Model Using Computed Tomography Scans.

Pancreatic tumor is a lethal kind of tumor and its prediction is really poor in the current scenario. Automated pancreatic tumor classification using ...

A Deep Learning Framework for Automatic Meal Detection and Estimation in Artificial Pancreas Systems.

Current artificial pancreas (AP) systems are hybrid closed-loop systems that require manual meal announcements to manage postprandial glucose control ...

Deep learning-based pancreas volume assessment in individuals with type 1 diabetes.

Pancreas volume is reduced in individuals with diabetes and in autoantibody positive individuals at high risk for developing type 1 diabetes (T1D). St...

Model-Driven Deep Learning Method for Pancreatic Cancer Segmentation Based on Spiral-Transformation.

Pancreatic cancer is a lethal malignant tumor with one of the worst prognoses. Accurate segmentation of pancreatic cancer is vital in clinical diagnos...

Automatic Pancreatic Cyst Lesion Segmentation on EUS Images Using a Deep-Learning Approach.

The automatic segmentation of the pancreatic cyst lesion (PCL) is essential for the automated diagnosis of pancreatic cyst lesions on endoscopic ultra...

Assessing and utilizing esterase specificity in antimicrobial prodrug development.

As a class of enzymes, esterases have been investigated for decades and have found use in industrial processes, synthetic organic chemistry, and elsew...

Multi-scale Selection and Multi-channel Fusion Model for Pancreas Segmentation Using Adversarial Deep Convolutional Nets.

Organ segmentation from existing imaging is vital to the medical image analysis and disease diagnosis. However, the boundary shapes and area sizes of ...

Determination of multiple drugs of abuse in human urine using dispersive liquid-liquid microextraction and capillary electrophoresis with PDA detection.

A new method was developed for pre-concentration and determination of multiple drugs of abuse in human urine using dispersive liquid-liquid microextra...

Training in robotic Hepatobiliary and pancreatic surgery: a step up approach.

ROBOT-assisted pancreatoduodenectomy in 300 consecutive cases: Annual trend analysis and propensity score-matched comparison of perioperative and long-term oncologic outcomes with the open method.

BACKGROUND/PURPOSE: We previously reported perioperative and oncologic outcomes of robot-assisted pancreatoduodenectomy (RAPD); however, the follow-up...