Pancreatic Diseases

Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls.

OBJECTIVES: Pediatric acute pancreatitis (AP), Crohn's disease (CD), and irritable bowel syndrome (I...

User Perspectives on Conversational Agents for Preventive Alcohol Self-Help: Qualitative Exploratory Study.

BACKGROUND: Alcohol use remains a major public health concern, and although preventive alcohol self-...

Interpretable single-cell machine learning identifies PINK1-centred mitophagy as a determinant of metabolic fitness in type 2 diabetes.

BACKGROUND: Progressive pancreatic β-cell dysfunction constitutes a hallmark of type 2 diabetes (T2D...

Deep learning-based respiratory-triggered magnetic resonance cholangiopancreatography: comparison with conventional respiratory-triggered and breath-hold magnetic resonance cholangiopancreatography.

PURPOSE: To evaluate whether deep learning-based respiratory-triggered (DL) 3D magnetic resonance ch...

Specimen quality shapes the actionable genomic landscape in comprehensive cancer genomic profiling.

Comprehensive genomic profiling (CGP) is widely used to identify actionable alterations and guide pr...

Development of non-destructive durian fruit maturity detection tool based on multi-variable sensor for harvest quality optimisation.

Durian maturity critically affects consumer acceptance, market value, and postharvest losses, yet it...

Explainable early prediction of short-term severe deterioration in gallstone-related biliary disease using MIMIC-IV, eICU, and local real-world data.

BACKGROUND: Patients with gallstone-related biliary disease may deteriorate rapidly before definitiv...

Hydrophobic deep eutectic solvent-based green sample pretreatment strategy for chromatographic-mass spectrometric analysis of anthraquinones from Rheum palmatum L․.

Anthraquinones from Rheum palmatum L. possess diverse pharmacological activities; however, their int...

Periodic surveillance of intraductal papillary mucinous neoplasms: gaps in evidence and future directions.

Intraductal papillary mucinous neoplasm (IPMN) is a well-established precursor to pancreatic cancer;...

Topological imaging of single-cell CAF heterogeneity for predicting prognosis and adjuvant chemotherapy benefit in pancreatic cancer.

PURPOSE: Cancer-associated fibroblasts (CAFs) are central drivers of PDAC progression and therapeuti...

Week-Ahead Prediction of High-Risk Drinking Episodes Among Young Adults Using Wearable Biosignals and Psychological Vulnerabilities: Prospective Observational Machine Learning Study.

BACKGROUND: Although machine learning has increasingly been used to predict mental health symptoms a...

Using Machine Learning with the Brief Symptom Inventory to Screen for Comorbid Addictions: A Proof-of-Principle Study.

INTRODUCTION: Mental health disorders are leading causes of morbidity worldwide and often co-occur w...

Factors contributing to the missed diagnosis of incidental gallbladder cancer (IGBC): an integrated analysis of clinical features and ultrasound radiomics.

BACKGROUND: Incidental gallbladder cancer (IGBC) is often diagnosed only during or after cholecystec...

Machine Learning-Based Identification of Survival-Associated CpG Biomarkers in Pancreatic Ductal Adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) is an exceptionally aggressive cancer with a 5-year survival...

Where You Live Shapes Diabetes Risk: Multilevel Determinants of Type 2 Diabetes in the East South Central United States.

Type 2 diabetes melittus (T2DM) remains a major public health challenge in the United States, partic...

Global Geospatial Trends in Breast Cancer and Atrial Fibrillation/Flutter Among Older Women: Uncovering Shared Epidemiological Patterns and Etiological Links.

BACKGROUND: Breast cancer (BC) and atrial fibrillation (AF) represent increasing global health burde...

Spiky Magnetic Titania Particles for Integrated Exosome Capture and Metabolic Profiling Toward Cancer Diagnosis.

Exosomal metabolite profiling represents a promising non-invasive approach for cancer diagnosis. How...

Perioperative corticosteroids and pancreatic surgery outcomes: a systematic review and meta-analysis combining human expertise and AI support (ChatGPT).

Pancreatic surgery is associated with high postoperative morbidity. The role of corticosteroids (CCS...

Real-Time AI-Based Alert System for Head Occlusion: Ensuring Video Quality for Hepato-Biliary-Pancreatic Board Certification.

Deep learning-based automatic identification model of main pancreatic duct in intraoperative ultrasonography.

BACKGROUND: Pancreatic enucleation (PE) preserves parenchyma in benign/low-grade malignant pancreati...

Hearing Loss in Older Adults: Consistent Determinants Across Two Community-Based Cohorts in Southern China.

BACKGROUND: Hearing loss (HL) is common in older adults and is associated with substantial functiona...