Neurology

Parkinson's Disease

Latest AI and machine learning research in parkinson's disease for healthcare professionals.

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Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorder.

BACKGROUND: Synucleinopathies include a spectrum of disorders varying in features and severity, including idiopathic/isolated REM sleep behaviour disorder (iRBD), Parkinson's disease (PD), and dementia with Lewy bodies (DLB). Distinct brain atrophy patterns may already be seen in iRBD; however, how brain atrophy begins and progresses remains unclear.

May 29 2025 40447483

An Artificial Intelligence Olfactory-Based Diagnostic Model for Parkinson's Disease Using Volatile Organic Compounds from Ear Canal Secretions.

Parkinson's Disease (PD), a frequently diagnosed neurodegenerative condition, poses a major global challenge. Early diagnosis and intervention are crucial for PD treatment. This study proposes a diagnostic model for PD that analyzes volatile organic compounds (VOCs) from ear canal secretions (ECS). Using gas chromatography-mass spectrometry (GC-MS) to examine ECS samples from patients, four VOC co...

May 28 2025 40435384
Personalized prediction of gait freezing using dynamic mode decomposition.

Freezing of gait (FoG) is a common severe gait disorder in patients with advanced Parkinson's disease. The ability to predict the onset of FoG episode...

May 28 2025 40437121
Detecting Tardive Dyskinesia Using Video-Based Artificial Intelligence.

Tardive dyskinesia (TD) is a late-onset adverse effect of dopamine receptor-blocking medications, characterized by involuntary movements primarily af...

May 28 2025 40488727
Automatic identification of Parkinsonism using clinical multi-contrast brain MRI: a large self-supervised vision foundation model strategy.

BACKGROUND: Valid non-invasive biomarkers for Parkinson's disease (PD) and Parkinson-plus syndrome (PPS) are urgently needed. Based on our recent self...

May 27 2025 40435723
A Pilot Study Comparing Speech Characteristics in People With Parkinson's Disease and Controls Dancing Weekly Over 5-Years.

INTRODUCTION: Parkinson's Disease (PD) is a neurodegenerative disorder that affects motor and non-motor functions. Speech impairments, such as reduced...

May 27 2025 40436695
The Role of AI in the Management of Movement Disorders.

Artificial intelligence (AI) has emerged as a transformative force in the management of movement disorders. This review explores the various applicati...

May 26 2025 40300751
Gait analysis for Parkinson's disease using multiscale entropy.

Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by motor dysfunction and complex gait abnormalities. Traditional linear me...

May 26 2025 40415583
Brain age prediction from MRI scans in neurodegenerative diseases.

PURPOSE OF REVIEW: This review explores the use of brain age estimation from MRI scans as a biomarker of brain health. With disorders like Alzheimer's...

May 22 2025 40396549
Novel Voice Signal Segmentation Based on Clark Distance to Improve Intelligent Parkinson Disease Detection.

This paper presents a novel classifier based on the Clark distance for early detection of Parkinson's disease (PD) using voice data. The nonlinear nat...

May 22 2025 40410058
Diagnostic Accuracy of Machine Learning-Assisted MRI for Mild Cognitive Impairment in Parkinson's Disease: A Systematic Review and Meta-Analysis.

To evaluate the diagnostic accuracy of machine learning-assisted magnetic resonance imaging (MRI) in detecting cognitive impairment among Parkinson's ...

May 22 2025 40443718
The Role of HbA1c in Parkinson's Disease: An Integrative Analysis by Single-Cell, Bulk Transcriptome and Mendelian Randomization.

Decreased glucose tolerance is recognized as a factor associated with Parkinson's disease (PD) progression, yet the relationship between HbA1c and PD ...

May 21 2025 40397357
Exploring the landscape of Parkinson's disease transcriptomics: a quantitative review of research progress and future directions.

INTRODUCTION: This study leverages bibliometric analysis to uncover the research landscape and spotlight emerging trends in the field of Parkinson's d...

May 21 2025 40469842
Recent advances (2022-2024) in eye-tracking for Parkinson's disease: a promising tool for diagnosing and monitoring symptoms.

INTRODUCTION: Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders, characterized by both motor and non-motor symptoms, i...

May 21 2025 40469846
Mapping the structure-function landscape of semiconducting polymers.

The molecular design of semiconducting polymers (SCPs) has been largely guided by varying monomer combinations and sequences by leveraging a robust un...

May 20 2025 40390597
FDG-PET as a pre-operative biomarker for predicting and optimizing response to subcallosal cingulate area deep brain stimulation.

BACKGROUND: Deep brain stimulation targeting the subcallosal cingulate area (SCC-DBS) has emerged as a promising therapy for treatment-resistant depre...

May 20 2025 40403825
QSPR analysis of physico-chemical and pharmacological properties of medications for Parkinson's treatment utilizing neighborhood degree-based topological descriptors.

Topological indices are invariant quantitative metrics associated with a molecular graph, which characterize the bonding topology of a molecule. The m...

May 15 2025 40374678
Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson's disease.

There is strong interest in using the gut microbiome for Parkinson's disease (PD) diagnosis and treatment. However, a consensus on PD-associated micro...

May 7 2025 40335465
Efficient, Robust, and Accurate CNN Predictor for Neuronal Activation in Directional Deep Brain Stimulation.

The programming of clinical deep brain stimulation (DBS) systems involves numerous combinations of stimulation parameters, such as stimulus amplitude,...

May 7 2025 40232895
Enhancing Neurodegenerative Disease Diagnosis Through Confidence-Driven Dynamic Spatio-Temporal Convolutional Network.

Dynamic brain networks are more effective than static networks in characterizing the evolving patterns of brain functional connectivity, making them a...

May 7 2025 40293889
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