Parkinson's Disease

Haptic Feedback Manipulation During Botulinum Toxin Injection Therapy for Focal Hand Dystonia Patients: A Possible New Assistive Strategy.

Abnormality of sensorimotor integration in the basal ganglia and cortex has been reported in the lit...

Machine learning for large-scale wearable sensor data in Parkinson's disease: Concepts, promises, pitfalls, and futures.

For the treatment and monitoring of Parkinson's disease (PD) to be scientific, a key requirement is ...

Functional Relevance of Different Basal Ganglia Pathways Investigated in a Spiking Model with Reward Dependent Plasticity.

The brain enables animals to behaviorally adapt in order to survive in a complex and dynamic environ...

Basal Ganglia dysfunctions in movement disorders: What can be learned from computational simulations.

The basal ganglia are a complex neuronal system that is impaired in several movement disorders, incl...

Joint feature-sample selection and robust diagnosis of Parkinson's disease from MRI data.

Parkinson's disease (PD) is an overwhelming neurodegenerative disorder caused by deterioration of a ...

Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem.

Automated segmentation is a useful method for studying large brain structures such as the cerebellum...

Folded concave penalized learning in identifying multimodal MRI marker for Parkinson's disease.

BACKGROUND: Brain MRI holds promise to gauge different aspects of Parkinson's disease (PD)-related p...

Test and Validation of a Smart Exercise Bike for Motor Rehabilitation in Individuals With Parkinson's Disease.

To assess and validate the Smart Exercise Bike designed for Parkinson's Disease (PD) rehabilitation,...

Symmetry Analysis of Gait between Left and Right Limb Using Cross-Fuzzy Entropy.

The purpose of this paper is the investigation of gait symmetry problem by using cross-fuzzy entropy...

A Q-backpropagated time delay neural network for diagnosing severity of gait disturbances in Parkinson's disease.

Parkinson's disease (PD) is a movement disorder that affects the patient's nervous system and health...

Robotic gait rehabilitation and substitution devices in neurological disorders: where are we now?

Gait abnormalities following neurological disorders are often disabling, negatively affecting patien...

Closed-Loop Modulation of the Pathological Disorders of the Basal Ganglia Network.

A generalized predictive closed-loop control strategy to improve the basal ganglia activity patterns...

Response to Dr. Cerasa's commentary on the article: "Unsupervised learning based feature extraction for differential diagnosis of neurodegenerative diseases: A case study on early-stage diagnosis of Parkinson disease".

Diagnosing Parkinson's Diseases Using Fuzzy Neural System.

This study presents the design of the recognition system that will discriminate between healthy peop...

Protective Effects of Streblus asper Leaf Extract on H2O2-Induced ROS in SK-N-SH Cells and MPTP-Induced Parkinson's Disease-Like Symptoms in C57BL/6 Mouse.

This study investigated the effects of Streblus asper leaf extract (SA) on reactive oxygen species (...

Measurement of viral load by the automated Abbott real-time HIV-1 assay using dried blood spots collected and processed in Malawi and Mozambique.

BACKGROUND: The use of dried blood spots (DBS) for HIV-1 viral load quantification can greatly impro...

Computer-Aided Diagnosis of Parkinson's Disease Using Enhanced Probabilistic Neural Network.

Early and accurate diagnosis of Parkinson's disease (PD) remains challenging. Neuropathological stud...

PDON: Parkinson's disease ontology for representation and modeling of the Parkinson's disease knowledge domain.

BACKGROUND: Despite the unprecedented and increasing amount of data, relatively little progress has ...

A Method for Automatic and Objective Scoring of Bradykinesia Using Orientation Sensors and Classification Algorithms.

Correct assessment of bradykinesia is a key element in the diagnosis and monitoring of Parkinson's d...

A Fuzzy Inference System for Closed-Loop Deep Brain Stimulation in Parkinson's Disease.

Parkinsons disease is a complex neurodegenerative disorder for which patients present many symptoms,...

Machine learning classification of medication adherence in patients with movement disorders using non-wearable sensors.

Medication non-adherence is a major concern in the healthcare industry and has led to increases in h...