Neurology

Parkinson's Disease

Latest AI and machine learning research in parkinson's disease for healthcare professionals.

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A Soft Gripper with Rigidity Tunable Elastomer Strips as Ligaments.

Like their natural counterparts, soft bioinspired robots capable of actively tuning their mechanical rigidity can rapidly transition between a broad range of motor tasks-from lifting heavy loads to dexterous manipulation of delicate objects. Reversible rigidity tuning also enables soft robot actuators to reroute their internal loading and alter their mode of deformation in response to intrinsic ac...

Jun 16 2017 29251572

Automatic Assessment of a Rollator-User's Condition During Rehabilitation Using the i-Walker Platform.

Patient condition during rehabilitation has been traditionally assessed using clinical scales. These scales typically require the patient and/or the clinician to rate a number of condition-related items to obtain a final score. This is a time-consuming task, specially if a large number of patients are involved. Furthermore, during rehabilitation, user condition is expected to change steadily in ti...

Apr 25 2017 28459694
A multilevel-ROI-features-based machine learning method for detection of morphometric biomarkers in Parkinson's disease.

Machine learning methods have been widely used in recent years for detection of neuroimaging biomarkers in regions of interest (ROIs) and assisting di...

Apr 21 2017 28435046
In-Situ Force Augmentation Improves Surface Contact and Force Control.

Surgeons routinely perform surgery with noisy, sub-threshold, or obscured visual and haptic feedback, either due to the necessary surgical approach, o...

Apr 21 2017 28436890
An automatic non-invasive method for Parkinson's disease classification.

BACKGROUND AND OBJECTIVE: The automatic noninvasive identification of Parkinson's disease (PD) is attractive to clinicians and neuroscientist. Various...

Apr 18 2017 28552119
Feasibility of spirography features for objective assessment of motor function in Parkinson's disease.

OBJECTIVE: Parkinson's disease (PD) is currently incurable, however proper treatment can ease the symptoms and significantly improve the quality of li...

Mar 31 2017 28416144
Discriminating cognitive status in Parkinson's disease through functional connectomics and machine learning.

There is growing interest in the potential of neuroimaging to help develop non-invasive biomarkers in neurodegenerative diseases. In this study, conne...

Mar 28 2017 28349948
Mimicking Neurotransmitter Release in Chemical Synapses via Hysteresis Engineering in MoS Transistors.

Neurotransmitter release in chemical synapses is fundamental to diverse brain functions such as motor action, learning, cognition, emotion, perception...

Mar 10 2017 28260370
Metric learning for Parkinsonian identification from IMU gait measurements.

Diagnosis of people with mild Parkinson's symptoms is difficult. Nevertheless, variations in gait pattern can be utilised to this purpose, when measur...

Feb 27 2017 28288333
Analysis of facial expressions in parkinson's disease through video-based automatic methods.

BACKGROUND: The automatic analysis of facial expressions is an evolving field that finds several clinical applications. One of these applications is t...

Feb 20 2017 28223023
Home detection of freezing of gait using support vector machines through a single waist-worn triaxial accelerometer.

Among Parkinson's disease (PD) symptoms, freezing of gait (FoG) is one of the most debilitating. To assess FoG, current clinical practice mostly emplo...

Feb 15 2017 28199357
Robotic-assisted gait training in Parkinson's disease: a three-month follow-up randomized clinical trial.

PURPOSE: The aim of this study was to evaluate the efficacy of a robotic-assisted gait training (RAGT), together with a conventional exercise program ...

Feb 13 2017 28132574
Efficient implementation of a real-time estimation system for thalamocortical hidden Parkinsonian properties.

Real-time estimation of dynamical characteristics of thalamocortical cells, such as dynamics of ion channels and membrane potentials, is useful and es...

Jan 9 2017 28065938
Quantification of the 3α and 3β epimers of 25-hydroxyvitamin D in dried blood spots by LC-MS/MS using artificial whole blood calibration and chemical derivatization.

While the biological function of the 3α epimer of 25-hydroxyvitamin D (25(OH)D) remains unknown, its presence needs to be accurately captured and sepa...

Dec 28 2016 28153274
A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes.

There is a clear need for drug treatments to be selected according to the characteristics of an individual patient, in order to improve efficacy and r...

Dec 23 2016 28066248
Glycosaminoglycan levels in dried blood spots of patients with mucopolysaccharidoses and mucolipidoses.

UNLABELLED: Mucopolysaccharidoses (MPSs) and mucolipidoses (ML) are groups of lysosomal storage disorders in which lysosomal hydrolases are deficient ...

Dec 22 2016 28065440
Classification of Parkinson's disease utilizing multi-edit nearest-neighbor and ensemble learning algorithms with speech samples.

BACKGROUND: The use of speech based data in the classification of Parkinson disease (PD) has been shown to provide an effect, non-invasive mode of cla...

Nov 16 2016 27852279
Impact of Cognitive Loading on Postural Control in Parkinson's Disease With Freezing of Gait.

To assess standing balance in Parkinson's disease (PD) patients with and without freezing of gait (FOG) during cognitive loading. A balance assessment...

Nov 3 2016 28680941
Stop! border ahead: Automatic detection of subthalamic exit during deep brain stimulation surgery.

BACKGROUND: Microelectrode recordings along preplanned trajectories are often used for accurate definition of the subthalamic nucleus (STN) borders du...

Oct 6 2016 27709666
Feature Selection Based on Iterative Canonical Correlation Analysis for Automatic Diagnosis of Parkinson's Disease.

Parkinson's disease (PD) is a major progressive neurodegenerative disorder. Accurate diagnosis of PD is crucial to control the symptoms appropriately....

Oct 2 2016 28593202
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