Neurology

Parkinson's Disease

Latest AI and machine learning research in parkinson's disease for healthcare professionals.

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Showing 1321-1340 of 7,179 articles

Application and assessment of deep learning for the generation of potential NMDA receptor antagonists.

Uncompetitive antagonists of the N-methyl d-aspartate receptor (NMDAR) have demonstrated therapeutic benefit in the treatment of neurological diseases such as Parkinson's and Alzheimer's, but some also cause dissociative effects that have led to the synthesis of illicit drugs. The ability to generate NMDAR antagonists in silico is therefore desirable for both new medication development and preempt...

Jan 21 2021 33355332

Robot-Assisted Stereotaxy Reduces Target Error: A Meta-Analysis and Meta-Regression of 6056 Trajectories.

BACKGROUND: The pursuit of improved accuracy for localization and electrode implantation in deep brain stimulation (DBS) and stereoelectroencephalography (sEEG) has fostered an abundance of disparate surgical/stereotactic practices. Specific practices/technologies directly modify implantation accuracy; however, no study has described their respective influence in multivariable context.

Jan 13 2021 33045739
Man-machine interaction-based motion control of a robotic walker.

BACKGROUND: The aging population brings the problem of healthcare and dyskinesia. The lack of mobility extremely affects stroke patient's activities o...

Jan 1 2021 33074202
Video-Based Analyses of Parkinson's Disease Severity: A Brief Review.

Remote and objective assessment of the motor symptoms of Parkinson's disease is an area of great interest particularly since the COVID-19 crisis emerg...

Jan 1 2021 33682727
Will Artificial Intelligence Replace the Movement Disorders Specialist for Diagnosing and Managing Parkinson's Disease?

The use of artificial intelligence (AI) to help diagnose and manage disease is of increasing interest to researchers and clinicians. Volumes of health...

Jan 1 2021 34219671
Two Hundred Twenty-Six Consecutive Deep Brain Stimulation Electrodes Placed Using an "Asleep" Technique and the Neuro|MateTM Robot for the Treatment of Movement Disorders.

BACKGROUND: Robotics in neurosurgery has demonstrated widening indications and rapid growth in recent years. Robotic precision and reproducibility are...

Oct 15 2020 32629477
Computational framework for detection of subtypes of neuropsychiatric disorders based on DTI-derived anatomical connectivity.

Many brain disorders - such as Alzheimer's disease, Parkinson's disease, schizophrenia and autism - are heterogeneous, that is, they may have several ...

Oct 1 2020 32894990
Automated Detection of Enhanced DBS Device Settings.

Continuous deep brain stimulation (DBS) of the ventral striatum (VS) is an effective treatment for severe, treatment-refractory obsessive-compulsive d...

Oct 1 2020 33937916
Frameless ROSA® Robot-Assisted Lead Implantation for Deep Brain Stimulation: Technique and Accuracy.

BACKGROUND: Frameless robotic-assisted surgery is an innovative technique for deep brain stimulation (DBS) that has not been assessed in a large cohor...

Jul 1 2020 31647105
Parkinson's Disease Classification using Pitch Synchronous Speech Segments and Fine Gaussian Kernels based SVM.

Researchers have been using signal processing based methods to assess speech from Parkinson's disease (PD) patients and identify the contrasting featu...

Jul 1 2020 33017972
Predicting Early Stage Drug Induced Parkinsonism using Unsupervised and Supervised Machine Learning.

Drug Induced Parkinsonism (DIP) is the most common, debilitating movement disorder induced by antipsychotics. There is no tool available in clinical p...

Jul 1 2020 33018101
The Smart Device System for Movement Disorders: Preliminary Evaluation of Diagnostic Accuracy in a Prospective Study.

Consumer wearables can provide objective monitoring of movement disorders and may identify new phenotypical biomarkers. We present a novel smartwatch-...

Jun 16 2020 32570510
Image-guidance, Robotics, and the Future of Spine Surgery.

Spine surgery has seen considerable advancements over the last 2 decades, particularly in the fields of image-guidance and robotics. These technologie...

Jun 1 2020 31425306
Robotic Deep Brain Stimulation (R-DBS)-"Awake" Deep Brain Stimulation Using the Neuromate Robot and O-Arm.

BACKGROUND: Deep brain stimulation (DBS) is an effective surgical technique used to ameliorate the motor symptoms associated with Parkinson's disease....

Jan 1 2020 33318371
Quadruple Decision Making for Parkinson's Disease Patients: Combining Expert Opinion, Patient Preferences, Scientific Evidence, and Big Data Approaches to Reach Precision Medicine.

Clinical decision making for Parkinson's disease patients is supported by a combination of three distinct information resources: best available scient...

Jan 1 2020 31561387
Technology-Based Objective Measures Detect Subclinical Axial Signs in Untreated, de novo Parkinson's Disease.

BACKGROUND: Technology-based objective measures (TOMs) recently gained relevance to support clinicians in the assessment of motor function in Parkinso...

Jan 1 2020 31594252
Addressing the Credit Assignment Problem in Treatment Outcome Prediction using Temporal Difference Learning.

Mental health patients often undergo a variety of treatments before finding an effective one. Improved prediction of treatment response can shorten th...

Jan 1 2020 31797585
High-accuracy Automated Diagnosis of Parkinson's Disease.

PURPOSE: Parkinson's disease (PD), which is the second most common neurodegenerative disease following Alzheimer's disease, can be diagnosed clinicall...

Jan 1 2020 32723240
Automatic substantia nigra segmentation in neuromelanin-sensitive MRI by deep neural network in patients with prodromal and manifest synucleinopathy.

Neuromelanin (NM) is a black pigment located in the brain in substantia nigra pars compacta (SN) and locus coeruleus. Its loss is directly connected t...

Dec 30 2019 32118476
[Advances in the development of otologic surgery robots].

In recent decades, surgical robots have made great progress and are widely used in many clinical departments.It can eliminate the doctor's hands tremo...

Dec 7 2019 31887825
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