Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Deep active learning for classifying cancer pathology reports.

BACKGROUND: Automated text classification has many important applications in the clinical setting; however, obtaining labelled data for training machine learning and deep learning models is often difficult and expensive. Active learning techniques may mitigate this challenge by reducing the amount of labelled data required to effectively train a model. In this study, we analyze the effectiveness o...

Mar 9 2021 33750288

A robust electrochemical immunosensor based on core-shell nanostructured silica-coated silver for cancer (carcinoembryonic-antigen-CEA) diagnosis.

This work addresses the fabrication of an efficient, novel, and economically viable immunosensing armamentarium that will detect the carcinoembryonic antigen (CEA) typically associated with solid tumors (sarcomas, carcinomas, and lymphomas) and is used as a clinical tumor marker for all these malignancies. We synthesized silver nanoparticles by single-step chemical reduction and coated with silica...

Mar 9 2021 35423536
Artificial intelligence and algorithmic computational pathology: an introduction with renal allograft examples.

Whole slide imaging, which is an important technique in the field of digital pathology, has recently been the subject of increased interest and avenue...

Mar 8 2021 33211332
Micro-morphological feature visualization, auto-classification, and evolution quantitative analysis of tumors by using SR-PCT.

Tissue micro-morphological abnormalities and interrelated quantitative data can provide immediate evidences for tumorigenesis and metastasis in microe...

Mar 7 2021 33682368
A deep learning approach for mitosis detection: Application in tumor proliferation prediction from whole slide images.

The tumor proliferation, which is correlated with tumor grade, is a crucial biomarker indicative of breast cancer patients' prognosis. The most common...

Mar 6 2021 33875159
A novel lightweight deep convolutional neural network for early detection of oral cancer.

OBJECTIVES: To develop a lightweight deep convolutional neural network (CNN) for binary classification of oral lesions into benign and malignant or po...

Mar 5 2021 33636041
Prediction of the histology of colorectal neoplasm in white light colonoscopic images using deep learning algorithms.

The treatment plan of colorectal neoplasm differs based on histology. Although new endoscopic imaging systems have been developed, there are clear dia...

Mar 5 2021 33674628
Frameless stereotactic brain biopsy: A prospective study on robot-assisted brain biopsies performed on 32 patients by using the RONNA G4 system.

BACKGROUND: We present a novel robotic neuronavigation system (RONNA G4), used for precise preoperative planning and frameless neuronavigation, develo...

Mar 4 2021 33591608
Computer-aided diagnosis of ground glass pulmonary nodule by fusing deep learning and radiomics features.

OBJECTIVES: This study aims to develop a computer-aided diagnosis (CADx) scheme to classify between benign and malignant ground glass nodules (GGNs), ...

Mar 4 2021 33596552
Therapeutic Potentials of Selected Antihypertensive Agents and Their Fixed-Dose Combinations Against Trastuzumab-Mediated Cardiotoxicity.

Trastuzumab () is useful in the clinical management of HER2-positive metastatic breast, gastric, and colorectal carcinoma but has been limited by its ...

Mar 4 2021 33897413
HistoNet: A Deep Learning-Based Model of Normal Histology.

We introduce HistoNet, a deep neural network trained on normal tissue. On 1690 slides with rat tissue samples from 6 preclinical toxicology studies, t...

Mar 3 2021 33653171
Whole-slide margin control through deep learning in Mohs micrographic surgery for basal cell carcinoma.

BACKGROUND: Basal cell carcinoma (BCC) is the most common type of skin cancer with incidence rates rising each year. Mohs micrographic surgery (MMS) i...

Mar 3 2021 33656186
Deep learning systems detect dysplasia with human-like accuracy using histopathology and probe-based confocal laser endomicroscopy.

Probe-based confocal laser endomicroscopy (pCLE) allows for real-time diagnosis of dysplasia and cancer in Barrett's esophagus (BE) but is limited by ...

Mar 3 2021 33658592
Super-Resolution Ultrasound Localization Microscopy Through Deep Learning.

Ultrasound localization microscopy has enabled super-resolution vascular imaging through precise localization of individual ultrasound contrast agents...

Mar 2 2021 33180723
DeepMIB: User-friendly and open-source software for training of deep learning network for biological image segmentation.

We present DeepMIB, a new software package that is capable of training convolutional neural networks for segmentation of multidimensional microscopy d...

Mar 2 2021 33651804
Machine Learning in Preoperative Prediction of Postoperative Immediate Remission of Histology-Positive Cushing's Disease.

BACKGROUND: There are no established accurate models that use machine learning (ML) methods to preoperatively predict immediate remission after transs...

Mar 2 2021 33737912
Data-efficient and weakly supervised computational pathology on whole-slide images.

Deep-learning methods for computational pathology require either manual annotation of gigapixel whole-slide images (WSIs) or large datasets of WSIs wi...

Mar 1 2021 33649564
Point-of-Care Digital Cytology With Artificial Intelligence for Cervical Cancer Screening in a Resource-Limited Setting.

IMPORTANCE: Cervical cancer is highly preventable but remains a common and deadly cancer in areas without screening programs. The creation of a diagno...

Mar 1 2021 33729503
A fault diagnosis method based on Auxiliary Classifier Generative Adversarial Network for rolling bearing.

Rolling bearing fault diagnosis is one of the challenging tasks and hot research topics in the condition monitoring and fault diagnosis of rotating ma...

Mar 1 2021 33647055
Deep Learning Whole-Gland and Zonal Prostate Segmentation on a Public MRI Dataset.

BACKGROUND: Prostate volume, as determined by magnetic resonance imaging (MRI), is a useful biomarker both for distinguishing between benign and malig...

Feb 26 2021 33634932
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