Latest AI and machine learning research in pathology for healthcare professionals.
BACKGROUND: Accurate preoperative differentiation between benign and malignant parotid gland tumors is essential for guiding surgical planning and treatment decisions. However, early-stage malignant tumors often lack distinctive imaging features on contrast-enhanced CT, making diagnosis challenging. PURPOSE: This study aimed to develop an artificial intelligence (AI)-assisted diagnostic system bas...
This paper addresses the challenge of multi-disease diagnosis by integrating causal reasoning into the diagnostic framework. In clinical practice, multiple conditions often co-occur, making multi-disease diagnosis more relevant than isolated single-disease cases. However, most deep learning methods focus on single-disease detection and fail to capture the complexity of diagnosing concurrent condit...
Predictions of pKa values provide insights into key aspects of molecular behavior, including solubility, lipophilicity, and binding affinity. Despite ...
Skin cancer (SC) is one of the most prevalent forms of cancer worldwide. Both melanoma and non-melanoma types pose major challenges for early detectio...
OBJECTIVE: Accurate prediction of postoperative facial appearance is essential for orthognathic surgical planning, yet remains challenging due to the ...
Non-muscle-invasive bladder cancer (NMIBC) has high rates of recurrence and progression, yet its molecular landscape across different ethnicities rema...
Microorganisms play significant roles in gastric cancer (GC) progression. However, it is unknown whether circulating microbiome DNA (cmDNA) possesses ...
Urinary extracellular vesicles (uEVs) are promising biomarkers for prostate cancer (PCa). Although novel uEV-based biomarkers have advanced early diag...
BACKGROUND: Breast cancer (BRCA) is the most common malignant tumor in women, with prognoses differing markedly by molecular subtype. Exercise is know...
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly lethal malignancy with high recurrence and limited therapies. Microvascular invasion (MVI) is a...
BACKGROUND: Environmental cadmium (Cd) pollution poses a severe threat to human health due to its strong bioaccumulation and high carcinogenicity. Alt...
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive subtype of primary liver cancer with insidious onset, early metastasis, and p...
BACKGROUND: Sperm morphology detection technology has important research value in diagnosing male infertility. Traditional manual detection methods ar...
BACKGROUND: The integration of clinical decision support tools in medical practice is challenging and must be carefully undertaken, especially in canc...
The dorsal root ganglion (DRG) is examined for sex-dependent phenotypes in sensory neurons, satellite glial cells (SGCs), and local macrophages follow...
BACKGROUND: Despite significant advancements in genetic diagnosis, there are still bottlenecks in DNA-level testing. Challenges to diagnosis include t...
BACKGROUND: Lactate promotes histone lactylation, which affects protein transcription and translation, thereby influencing tumour cell progression. Ho...
BACKGROUND: Neoadjuvant chemoradiotherapy (nCRT) is the standard treatment for locally advanced rectal cancer (LARC), yet clinically validated biomark...
BACKGROUND: Interstitial lung disease (ILD) represents a significant extra-articular complication associated with rheumatoid arthritis (RA), contribut...
PURPOSE: To enable the rapid generation of subject-specific whole-body anatomical models for patient-specific prediction of torso-local specific absor...