Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Current Advances in Spatial Pathology of Nasal Polyps: Challenges, Opportunities for Artificial Intelligence, and Future Directions.

Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by inflammatory heterogeneity, epithelial hyperplasia, and tissue remodeling, with spatial pathology critical for deciphering pathological mechanisms and guiding clinical practice. Conventional histopathological techniques rely on subjective visual evaluation, limited by inadequate spatial resolution of molecular markers and imprec...

Aug 27 2026 42662489

Ovarian borderline tumors and minimally invasive surgery: a narrative review.

Borderline ovarian tumors (BOTs) are a distinct subgroup of epithelial ovarian neoplasms that commonly affect women of reproductive age and are associated with excellent overall survival. Management is primarily surgical and requires balancing oncologic considerations with fertility preservation. This narrative review summarizes current evidence regarding pathology, molecular features, surgical ma...

Aug 27 2026 42664764
Cutaneous lymphomas - an update.

Primary cutaneous lymphomas (CL) and lymphoproliferative disorders (LPD) are heterogeneous T- and B-cell neoplasms defined by integrated clinical, his...

Aug 27 2026 42657966
Semi-Supervised Domain Adaptation with Latent Diffusion for Pathology Image Classification.

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches eith...

Aug 27 2026 42658697
Label-free ovarian cancer histopathological diagnosis using two-photon autofluorescence microscopy with a joint denoising and segmentation framework.

Two-photon autofluorescence (TPAF) microscopy is a promising modality for rapid, label-free assessment of unstained tissue, but is fundamentally limit...

Aug 27 2026 42649150
Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoids.

BACKGROUND: Lung neuroendocrine tumours (NETs, also known as carcinoids) are rapidly rising in incidence worldwide but have unknown aetiology and limi...

Aug 27 2026 42649496
AI-based segmentation of occult cervical lymph node metastases: potential reduction of cytokeratin staining.

BACKGROUND: Detection of occult cervical lymph node metastases is critical for accurate staging and treatment planning in oral cavity squamous cell ca...

Aug 27 2026 42656182
Detection of Pancreatic Cancer via Specific Metabolite Markers: A Metabolomics Approach.

BACKGROUND AND AIMS: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies worldwide because most patients are diagnosed...

Aug 26 2026 42661978
Translating evolutionary history and protein-focused machine learning supports increased prevalence of hereditary haemorrhagic telangiectasia, one of the most common inherited disorders.

BACKGROUND: Recent genetic data suggest hereditary haemorrhagic telangiectasia (HHT) is 2-12 times more common than the clinically-ascertained prevale...

Aug 26 2026 42644811
Detection of oral potentially malignant disorders and oral cancer with white light through deep learning: a systematic review and meta-analysis.

OBJECTIVES: The research question was: How accurate is artificial intelligence (AI) in diagnosing Oral Potentially Malignant Disorders (OPMD)/oral can...

Aug 26 2026 42645587
Incremental Diagnostic Value of Clinical Information for Large Language Models Across Multiple Organs: Retrospective Study.

BACKGROUND: Although large language models (LLMs) have demonstrated the ability to generate the impression section from radiology findings automatical...

Aug 26 2026 42647068
DeepPathway: Predicting Pathway Expression from Histopathology Images.

MOTIVATION: Spatial transcriptomics (ST) technologies provide spatially resolved gene expression along with image data, allowing the integrative analy...

Aug 26 2026 42647188
μNeuFMT: Background-Optical-Property-Adaptive Fluorescence Molecular Tomography via Implicit Neural Representation.

Fluorescence Molecular Tomography is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains cha...

Aug 26 2026 42647692
A novel approach for liver steatosis assessment in ultrasound images using an adapted Vision-Language Foundation Model.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is among the most prevalent chronic liver diseases worldwide. B-mode ultrasound remai...

Aug 26 2026 42648026
RNA biosensors in oncology: Mechanisms, Cancer-specific applications, and a Hallmark-aligned clinical roadmap.

Cancer diagnosis continues to rely on invasive tissue sampling and static molecular assessments that cannot reflect the real time RNA alterations driv...

Aug 26 2026 42648526
Achieving spatial multiomics diagonal integration from unaligned serial sections with DIME.

Learning integrated representations from spatial multiomics data is a fundamental challenge, particularly in the context of diagonal integration, wher...

Aug 26 2026 42648898
Noninvasive Profiling of the Glioma Vascular Microenvironment via 7T MRI: Decoding Angiogenic Signatures for Isocitrate Dehydrogenase and World Health Organization Grade Differentiation.

BACKGROUND: Accurate preoperative glioma grading and molecular subtyping are important for treatment. The vascular microenvironment promotes tumor pro...

Aug 26 2026 42649122
EndoVLM: A Vision-Language Assistant for Gastrointestinal Endoscopy.

Gastrointestinal endoscopy generates extensive high-resolution video data, posing significant challenges for efficient and accurate computer-aided dia...

Aug 26 2026 42649331
Deep Learning-Based Classification of NIFTP and Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma Using Gross Pathology Images.

Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and invasive encapsulated follicular variant of papillary thyroi...

Aug 26 2026 42649337
Herbarium specimens in the age of artificial intelligence: from herbarium image identification to Integrative Taxonomic AI.

Herbarium specimens are physical, verifiable records that form the basis of taxonomic knowledge and biodiversity research. Their large-scale digitizat...

Aug 26 2026 42642551
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