Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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EXPRESS: Convolutional Autoencoder for Automated Pre-Processing of Tumor Cell and Tissue Raman Spectra.

Raman spectroscopy (RS) is a label-free, non-destructive optical modality that provides a detailed p...

Feb 2026 41622963
Artificial Intelligence-Assisted Infrared Spectroscopy and Chemometrics for Enhanced Histopathology Screening of Micro- and Macrocancer Lesions.

Accurate detection of micro- and macrocancer lesions remains a critical challenge in histopathology,...

Feb 2026 41628021
ViT-Stain: Vision transformer-driven virtual staining for skin histopathology via global contextual learning.

Current virtual staining approaches for histopathology slides use convolutional neural networks (CNN...

Feb 2026 41628093
Single-cell transcriptomics and machine-learning reveal M1 macrophage-driven progression from minimal change disease to focal segmental glomerulosclerosis.

Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are two key nephrotic syn...

Feb 2026 41622775
Raman spectroscopy as the quantum eye to reveal molecular dynamics in biology.

Raman spectroscopy was a molecular vibrational spectroscopy technique based on inelastic light scatt...

Feb 2026 41637818
Time-Resolved Fluorescence and Diffuse Reflectance (TRF-DR) Spectroscopy for Heterogeneous Breast Tissue Classification and Tumor Margin Assessment.

Re-excision rates remain high for early-stage breast cancer patients due to challenges in margin del...

Feb 2026 41622347
SSDA_AOA: Stacked Sparse Denoising Autoencoder With Archimedes Optimization Algorithm Based Oral Cancer Detection on Histopathological Images.

OBJECTIVES: This study aims to address the challenges in the diagnosis of oral cancer by proposing a...

Feb 2026 41622690
Inferring tephritid fly pupal development stage using non-invasive near infrared imaging and machine learning classification.

Insect pupae change morphologically (e.g., pigmentation of eyes, wings, setae and legs) during the i...

Feb 2026 40920439
The Immuno-Metabolic Crosstalk in Lung Squamous Cell Carcinoma: Prognostic Insights and Therapeutic Clues.

Lung squamous cell carcinoma (LUSC) has a poor prognosis due to the lack of effective targeted thera...

Feb 2026 41606426
Targeted blood proteome profiling using NULISAseq identifies a high-performance biomarker panel for Aβ pathology quantification and staging.

INTRODUCTION: While current blood-based biomarkers for Alzheimer's disease (AD) are effective for de...

Feb 2026 41612914
Effects of ABO-Incompatible Blood Transfusion on Immune Response and Rejection After Organ Transplantation.

BACKGROUND: Peri-operative blood transfusion is common during solid-organ transplantation, yet the i...

Feb 2026 41618729
Classification of lung nodules in CT images based upon a multiplane dense inception network.

BACKGROUND: Lung cancer has been one of the leading causes of death in the world for decades. An eff...

Feb 2026 41619284
Machine learning model for fast prediction and uncertainty quantification of needle deflection during prostate biopsy.

BACKGROUND: Accurate needle placement is essential for prostate biopsy. Recently, transperineal pros...

Feb 2026 41619297
A comprehensive analysis reveals the molecular mechanisms linking preservatives to prostate cancer risk.

BACKGROUND: Preservatives, widely used in food and skincare products, may influence prostate cancer ...

Feb 2026 41620993
Disulfidptosis in osteoarthritis: Role of SLC2A3 downregulation and potential therapeutic implications.

OBJECTIVE: Disulfidptosis is a newly recognized form of regulated cell death characterized by actin ...

Jan 2026 41628840
C-X-C Motif Chemokine Ligand 3 as a Potential Biomarker for Diagnosis and Prognosis of Diabetic Kidney Disease.

Diabetic kidney disease (DKD) is the primary cause of end-stage renal disease globally, yet reliable...

Jan 2026 41524203
COL14A1 drives ischemic cardiac injury in PCOS: an artificial intelligence-identified biomarker.

BACKGROUND: Polycystic ovary syndrome (PCOS) and ischemic cardiomyopathy (ICM) share metabolic and c...

Jan 2026 41619759
ACACA modulates R-loop homeostasis to enhance lipid metabolism and microenvironmental interactions in ccRCC.

R-loops are dynamic nucleic acid structures implicated in genome regulation and instability, yet the...

Jan 2026 41620551
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