Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Evaluation of an Artificial Intelligence Defined Lung Nodule Malignancy Score in Incidental Pulmonary Nodules: The CREATE Study.

OBJECTIVE: To evaluate the effectiveness of the artificial intelligence-based qXR lung nodule malign...

Jan 2026 41716936
Validation of uPath HER2 dual-colour dual in-situ hybridisation image analysis tool for HER2/neu testing in breast cancer.

AIMS: HER2/neu gene is amplified in 15%-20% of invasive breast cancers (IBCs), serving as critical p...

Jan 2026 40921618
Artificial Intelligence-assisted Risk Stratification of Thyroid Nodules with Atypia of Undetermined Significance.

OBJECTIVE: Given the limitations of conventional approaches in managing indeterminate thyroid nodule...

Jan 2026 41553093
Spectral entropy variability of intraoperative electrocorticography predicts outcome after epilepsy surgery in people with focal cortical dysplasia.

OBJECTIVE: Epilepsy surgery in people with focal cortical dysplasia (FCD) requires accurate removal ...

Jan 2026 41553358
Hybrid imaging-clinical model for predicting microvascular invasion in hepatocellular carcinoma using deep learning-derived features from CT.

The role of adipose tissue in predicting microvascular invasion (MVI) in patients with hepatocellula...

Jan 2026 41553627
Fluorescence from dual molecular rotors allows sensitive detection of widespread brain pathology in a mouse model of Alzheimer's disease.

Amyloid fibrils formed by the misfolding and aggregation of proteins are a pathological hallmark of ...

Jan 2026 41553693
Morphometric analysis and its application in lupus nephritis: a systematic review.

Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), characterized ...

Jan 2026 41553994
Machine Learning for Predicting Malignant Transformation in Actinic Cheilitis: A Prognostic Support System Based on Demographic and Clinical Descriptors.

OBJECTIVE: This study aimed to develop and evaluate Machine Learning models to predict the malignant...

Jan 2026 41554686
UroFusion-X: a unified multimodal deep learning framework for robust diagnosis, subtyping, and prognosis of urological cancers.

Multimodal clinical data, including imaging, pathology, omics, and laboratory tests, are often fragm...

Jan 2026 41554842
Deep visual detection system for oral squamous cell carcinoma.

BACKGROUND: Oral Squamous Cell Carcinoma (OSCC) is a widespread and aggressive malignancy where earl...

Jan 2026 41554886
Computational methods for spatial multi-omics integration.

The rapid development of spatial multi-omics technologies has enabled the simultaneous acquisition o...

Jan 2026 41564956
CATERPillar: a flexible framework for generating white matter numerical substrates with incorporated glial cells.

Monte Carlo diffusion simulations in numerical substrates are valuable for exploring the sensitivity...

Jan 2026 41576825
Machine learning for extracellular vesicles enables diagnostic and therapeutic nanobiotechnology.

Extracellular vesicles (EVs) are emerging as naturally bioactive nanomaterials with intrinsic biocom...

Jan 2026 41546050
Accessible cartilage tumor malignancy prediction via vision-language foundation model adaptation.

OBJECTIVE: To predict cartilage tumor malignancy from radiographic images combined with readily avai...

Jan 2026 41547682
Japan Brain Bank Net (JBBN).

Autopsies have long been performed to determine the cause of death in the medical field. In fact, au...

Jan 2026 41542899
Cancer genome profiling in sarcomas: current status and future perspectives in Japan.

INTRODUCTION: Sarcomas are rare, molecularly diverse malignancies that challenge accurate diagnosis ...

Jan 2026 41543043
Multi-omics Mendelian randomization and machine learning identify candidate therapeutic targets for Alzheimer's and Parkinson's diseases.

Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), ...

Jan 2026 41543776
Automated 4D flow MRI pipeline for the quantification of advanced hemodynamic parameters in the left atrium.

The left atrium (LA) plays a pivotal role in modulating left ventricular filling, yet its hemodynami...

Jan 2026 41545408
Robust and interpretable prediction of gene markers and cell types from spatial transcriptomics data.

Spatial transcriptomics (ST) links tissue morphology with gene expression values, opening new avenue...

Jan 2026 41545411
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