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Prescriptions

Latest AI and machine learning research in prescriptions for healthcare professionals.

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Showing 3441-3460 of 9,093 articles

Exploring trends of nonmedical use of prescription drugs and polydrug abuse in the Twittersphere using unsupervised machine learning.

INTRODUCTION: Nonmedical use of prescription medications/drugs (NMUPD) is a serious public health threat, particularly in relation to the prescription opioid analgesics abuse epidemic. While attention to this problem has been growing, there remains an urgent need to develop novel strategies in the field of "digital epidemiology" to better identify, analyze and understand trends in NMUPD behavior.

Aug 17 2016 27568339

Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach.

Statistical analysis was performed on physicochemical descriptors of ∼250 drugs known to interact with one or more SLC22 "drug" transporters (i.e., SLC22A6 or OAT1, SLC22A8 or OAT3, SLC22A1 or OCT1, and SLC22A2 or OCT2), followed by application of machine-learning methods and wet laboratory testing of novel predictions. In addition to molecular charge, organic anion transporters (OATs) were found ...

Aug 3 2016 27488918
DeepFruits: A Fruit Detection System Using Deep Neural Networks.

This paper presents a novel approach to fruit detection using deep convolutional neural networks. The aim is to build an accurate, fast and reliable f...

Aug 3 2016 27527168
Protein-protein interaction network construction for cancer using a new L1/2-penalized Net-SVM model.

Identifying biomarker genes and characterizing interaction pathways with high-dimensional and low-sample size microarray data is a major challenge in ...

Jul 25 2016 27525863
Breast cancer-associated high-order SNP-SNP interaction of CXCL12/CXCR4-related genes by an improved multifactor dimensionality reduction (MDR-ER).

In association studies, the combined effects of single nucleotide polymorphism (SNP)-SNP interactions and the problem of imbalanced data between cases...

Jul 21 2016 27461876
Ethanol mediated As(III) adsorption onto Zn-loaded pinecone biochar: Experimental investigation, modeling, and optimization using hybrid artificial neural network-genetic algorithm approach.

Organic matters (OMs) and their oxidization products often influence the fate and transport of heavy metals in the subsurface aqueous systems through ...

Jul 5 2016 28391919
HPIDB 2.0: a curated database for host-pathogen interactions.

Identification and analysis of host-pathogen interactions (HPI) is essential to study infectious diseases. However, HPI data are sparse in existing mo...

Jul 3 2016 27374121
Development and characterization of methoxy poly(ethylene oxide)--poly(ε-caprolactone) (PEO--PCL) micelles as vehicles for the solubilization and delivery of tacrolimus.

Tacrolimus is a potent immunosuppressant; however, it suffers from several problems such as poor water solubility (4-12 μg/mL), low and variable oral ...

Jul 1 2016 28344477
Combining machine learning, crowdsourcing and expert knowledge to detect chemical-induced diseases in text.

Drug toxicity is a major concern for both regulatory agencies and the pharmaceutical industry. In this context, text-mining methods for the identifica...

Jun 15 2016 27307137
Multipolar Electrostatic Energy Prediction for all 20 Natural Amino Acids Using Kriging Machine Learning.

A machine learning method called kriging is applied to the set of all 20 naturally occurring amino acids. Kriging models are built that predict electr...

Jun 3 2016 27224739
Effect of goat milk on hepatotoxicity induced by antitubercular drugs in rats.

Aim of the present study was to assess the hepatoprotective activity of goat milk on antitubercular drug-induced hepatotoxicity in rats. Hepatotoxicit...

Jun 2 2016 28911608
Memory recall and spike-frequency adaptation.

The brain can reproduce memories from partial data; this ability is critical for memory recall. The process of memory recall has been studied using au...

May 13 2016 27300910
An immune-inspired swarm aggregation algorithm for self-healing swarm robotic systems.

Swarm robotics is concerned with the decentralised coordination of multiple robots having only limited communication and interaction abilities. Althou...

May 10 2016 27178784
Depolymerizable Poly(O-vinyl carbamate--sulfones) as Customizable Macromolecular Scaffolds for Mucosal Drug Delivery.

Interest in stimulus responsive materials and polymers has grown over the years, having shown great promise in a diverse set of applications. For drug...

May 4 2016 28480130
Protein-protein interaction inference based on semantic similarity of Gene Ontology terms.

Identifying protein-protein interactions is important in molecular biology. Experimental methods to this issue have their limitations, and computation...

Apr 23 2016 27117309
A New Feature Vector Based on Gene Ontology Terms for Protein-Protein Interaction Prediction.

Protein-protein interaction (PPI) plays a key role in understanding cellular mechanisms in different organisms. Many supervised classifiers like Rando...

Apr 20 2016 28113911
Chemical named entity recognition in patents by domain knowledge and unsupervised feature learning.

Medicinal chemistry patents contain rich information about chemical compounds. Although much effort has been devoted to extracting chemical entities f...

Apr 17 2016 27087307
Upper-Limb Robotic Exoskeletons for Neurorehabilitation: A Review on Control Strategies.

Since the late 1990s, there has been a burst of research on robotic devices for poststroke rehabilitation. Robot-mediated therapy produced improvement...

Apr 8 2016 27071194
Effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after oral administration.

BACKGROUND: Both ginsenoside Re and B-complex vitamins are widely used as nutritional supplements. They are often taken together so as to fully utiliz...

Apr 1 2016 28413326
tDCS and Robotics on Upper Limb Stroke Rehabilitation: Effect Modification by Stroke Duration and Type of Stroke.

Objective. The aim of this exploratory pilot study is to test the effects of bilateral tDCS combined with upper extremity robot-assisted therapy (RAT)...

Mar 31 2016 27123448
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