Preventive Care

Challenges in adapting existing clinical natural language processing systems to multiple, diverse health care settings.

OBJECTIVE: Widespread application of clinical natural language processing (NLP) systems requires taking existing NLP systems and adapting them to diverse and heterogeneous settings. We describe the challenges faced and lessons learned in adapting an existing NLP system for measuring colonoscopy quality.

Malignancy Detection on Mammography Using Dual Deep Convolutional Neural Networks and Genetically Discovered False Color Input Enhancement.

Breast cancer is the most prevalent malignancy in the US and the third highest cause of cancer-related mortality worldwide. Regular mammography screening has been attributed with doubling the rate of early cancer detection over the past three decades, yet estimates of mammographic accuracy in the hands of experienced radiologists remain suboptimal with sensitivity ranging from 62 to 87% and specif...

Development of a Robotic Colonoscopic Manipulation System, Using Haptic Feedback Algorithm.

PURPOSE: Colonoscopy is one of the most effective diagnostic and therapeutic tools for colorectal diseases. We aim to propose a master-slave robotic c...

Comparing the Human Papillomavirus Vaccination Opinions Trends from Different Twitter User Groups with a Machine Learning Based System and Semiparametric Nonlinear Regression.

HPV vaccination refusal is a serious public health issue. Opinions on Twitter have are influential to potential consumers on vaccination behaviours. P...

Cytomegalovirus Immunoglobulin G Avidity Index among Blood Donors in Alexandria, Egypt.

BACKGROUND AND AIM: Transfusion transmitted diseases (TTD) are a major challenge to transfusion services all over the world. Cytomegalovirus (CMV) is ...

Unsupervised selection of RV144 HIV vaccine-induced antibody features correlated to natural killer cell-mediated cytotoxic reactions.

HIV-1 vaccine injection has been shown less effective due to the diversity of antigens. Increasing the knowledge of the associations between immune sy...

Characterization of Architectural Distortion in Mammograms Based on Texture Analysis Using Support Vector Machine Classifier with Clinical Evaluation.

Architecture distortion (AD) is an important and early sign of breast cancer, but due to its subtlety, it is often missed on the screening mammograms....

Endowing a Content-Based Medical Image Retrieval System with Perceptual Similarity Using Ensemble Strategy.

Content-based medical image retrieval (CBMIR) is a powerful resource to improve differential computer-aided diagnosis. The major problem with CBMIR ap...

Towards a HPV Vaccine Knowledgebase for Patient Education Content.

Human papillomavirus is a widespread sexually transmitted infection that can be prevented with vaccination. However, HPV vaccination rates in the Unit...

Immune Response And Anamnestic Immune Response In Children After A 3-Dose Primary Hepatitis B Vaccination.

BACKGROUND: Diseases caused by Hepatitis B virus (HBV) have a worldwide distribution. Pakistan adopted the recommendations of World Health Organizatio...

HUMAN DNA QUANTIFICATION IN THE STOOLS OF PATIENTS WITH COLORECTAL CANCER.

BACKGROUND: Colorectal cancer is one of the main cause of cancer in the world. Colonoscopy is the best screen method, however the compliance is less t...

Measuring the quality of colonoscopy: Where are we now and where are we going?

Predicting selective liver X receptor β agonists using multiple machine learning methods.

Liver X receptor (LXR) α and β are cholesterol sensors; they respond to excess cholesterol and stimulate reverse cholesterol transport. Activating LXR...

A Study of Applications of Machine Learning Based Classification Methods for Virtual Screening of Lead Molecules.

The ligand-based virtual screening of combinatorial libraries employs a number of statistical modeling and machine learning methods. A comprehensive a...

Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.

Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in...

Classifying the Indication for Colonoscopy Procedures: A Comparison of NLP Approaches in a Diverse National Healthcare System.

In order to measure the level of utilization of colonoscopy procedures, identifying the primary indication for the procedure is required. Colonoscopie...

[A case report of hepatitis B virus reactivation in a hepatitis B core antibody-positive, hepatitis B surface antigen-negative hemodialysis patient].

Reactivation of the hepatitis B virus (HBV) has been reported in patients receiving immunosuppressive therapy or chemotherapy. We report a case of HBV...

Establishment of hepatitis A vaccine (inactivated, non-adsorbed) BRP batches 2 and 3.

The current hepatitis A vaccine (HAV), inactivated, non-adsorbed, European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) is used for...