Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Challenges and unmet needs in basal insulin therapy: lessons from the Asian experience.

Basal insulin therapy can improve glycemic control in people with type 2 diabetes. However, timely initiation, optimal titration, and proper adherence to prescribed basal insulin regimens are necessary to achieve optimal glycemic control. Even so, glycemic control may remain suboptimal in a significant proportion of patients. Unique circumstances in Asia (eg, limited resources, management of diabe...

Dec 15 2017 29276400

Aged black garlic extract regulates lipid metabolism by inhibiting lipogenesis and promoting lipolysis in mature 3T3-L1 adipocytes.

As the mechanism of aged black garlic (ABG) extract affecting lipid metabolism in adipocytes remains unclear, this study evaluated the effect of ABG extract on lipid metabolism and the expression of related proteins in mature 3T3-L1 adipocytes. ABG extract treatments at 0, 0.625, 1.25, and 2.5, and 5 mg/mL had no effect on cell morphology or viability in adipocytes. ABG extract suppressed lipogene...

Dec 12 2017 30263782
Putative identification of components in Zengye Decoction and their effects on glucose consumption and lipogenesis in insulin-induced insulin-resistant HepG2 cells.

Zengye Decoction (ZYD) is a well-known traditional medicine in China used for treating diseases associated with "Yin deficiency" such as diabetes. How...

Dec 12 2017 29272757
A novel method for predicting kidney stone type using ensemble learning.

The high morbidity rate associated with kidney stone disease, which is a silent killer, is one of the main concerns in healthcare systems all over the...

Dec 11 2017 29241659
Monitoring Patients on Metformin: Recent Changes and Rationales.

The Food and Drug Administration recently updated metformin prescribing recommendations for patients with diabetes and renal disease. The American Di...

Dec 10 2017 34860984
Increased Cardiovascular Risk in Patients with Adrenal Insufficiency: A Short Review.

Cardiovascular disease (CVD) is the most common cause of death in the world. Recent studies have shown an association between adrenal insufficiency (A...

Dec 10 2017 29376070
Anti-Lipase Potential of the Organic and Aqueous Extracts of Ten Traditional Edible and Medicinal Plants in Palestine; a Comparison Study with Orlistat.

Herbs have played a fundamental and essential role in the humans life since ancient times, especially those which are used as food and/or folk medici...

Dec 8 2017 29292744
Ensembles of Lasso Screening Rules.

In order to solve large-scale lasso problems, screening algorithms have been developed that discard features with zero coefficients based on a computa...

Nov 24 2017 29989981
l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.

Considering the pathologic importance of metabolic disturbances, advanced glycation end products (AGEs), and chronic inflammation in diabetes mellitus...

Nov 17 2017 29420997
Estimation of stress distribution in ferromagnetic tensile specimens using low cost eddy current stress measurement system and BP neural network.

Estimation of the stress distribution in ferromagnetic components is very important for evaluating the working status of mechanical equipment and impl...

Nov 16 2017 29145500
Predictions of ocular changes caused by diabetes in glaucoma patients.

BACKGROUND AND OBJECTIVE: This paper builds different neural network models with simple topologies, having one or two hidden layers which were subsequ...

Nov 15 2017 29249342
Endothelial markers in high altitude induced systemic hypertension (HASH) at moderate high altitude.

BACKGROUND: Chronic intermittent hypoxia is known to induce systemic arterial hypertension whereas chronic hypoxia causes pulmonary arterial hypertens...

Nov 15 2017 29386711
Modern drug design: the implication of using artificial neuronal networks and multiple molecular dynamic simulations.

We report the implementation of molecular modeling approaches developed as a part of the 2016 Grand Challenge 2, the blinded competition of computer a...

Nov 13 2017 29134430
A Machine Learning Ensemble Classifier for Early Prediction of Diabetic Retinopathy.

The main complication of diabetes is Diabetic retinopathy (DR), retinal vascular disease and it leads to the blindness. Regular screening for early DR...

Nov 9 2017 29124453
Radiomics and radiogenomics in lung cancer: A review for the clinician.

Lung cancer is responsible for a large proportion of cancer-related deaths across the globe, with delayed detection being perhaps the most significant...

Nov 8 2017 29290259
A fuzzy logic-based warning system for patients classification.

Typically acute deterioration in sick people is preceded by subtle changes in the physiological parameters such as pulse and blood pressure. The Modif...

Nov 6 2017 29108458
A Fully Automated Conversational Artificial Intelligence for Weight Loss: Longitudinal Observational Study Among Overweight and Obese Adults.

BACKGROUND: Type 2 diabetes is the most expensive chronic disease in the United States. Two-thirds of US adults have prediabetes or are overweight and...

Nov 1 2017 30291087
Development of a Reinforcement Learning-based Evolutionary Fuzzy Rule-Based System for diabetes diagnosis.

The early diagnosis of disease is critical to preventing the occurrence of severe complications. Diabetes is a serious health problem. A variety of me...

Oct 31 2017 29121541
Hypocalcemia and osteomalacia after bariatric surgery.

INTRODUCTION: Obesity has become a major health problem not only in industrialized societies but also in developing countries. Multiple studies have s...

Oct 25 2017 29263738
Comparison of Machine Learning Approaches Toward Assessing the Risk of Developing Cardiovascular Disease as a Long-Term Diabetes Complication.

The estimation of long-term diabetes complications risk is essential in the process of medical decision making. Guidelines for the management of Type ...

Oct 23 2017 29990007
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