Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Learning Optimal Personalized Treatment Rules in Consideration of Benefit and Risk: with an Application to Treating Type 2 Diabetes Patients with Insulin Therapies.

Individualized medical decision making is often complex due to patient treatment response heterogeneity. Pharmacotherapy may exhibit distinct efficacy and safety profiles for different patient populations. An "optimal" treatment that maximizes clinical benefit for a patient may also lead to concern of safety due to a high risk of adverse events. Thus, to guide individualized clinical decision maki...

Mar 31 2017 30034060

Screening of autism based on task-free fMRI using graph theoretical approach.

Studies on autism spectrum disorder (ASD) have indicated several dysfunctions in the structure, and functional organization of the brain. However, findings have not been established as a general diagnostic tool yet. In this regard, current study proposed an automatic screening method for recognition of ASDs from healthy controls (HCs) based on their brain functional abnormalities. In this paradigm...

Mar 9 2017 28324694
predCar-site: Carbonylation sites prediction in proteins using support vector machine with resolving data imbalanced issue.

The carbonylation is found as an irreversible post-translational modification and considered a biomarker of oxidative stress. It plays major role not ...

Mar 9 2017 28286168
Two-way learning with one-way supervision for gene expression data.

BACKGROUND: A family of parsimonious Gaussian mixture models for the biclustering of gene expression data is introduced. Biclustering is accommodated ...

Mar 4 2017 28257645
Polymorphism of angiotensin-converting enzyme (rs4340) and diabetic nephropathy in Caucasians with type 2 diabetes mellitus.

Diabetic nephropathy (DN) is the leading cause of endstage renal disease (ESRD) in developed countries. Several environmental and genetic factors pred...

Mar 4 2017 28289586
Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection Fraction.

We sought to evaluate whether unbiased machine learning of dense phenotypic data ("phenomapping") could identify distinct hypertension subgroups that ...

Mar 3 2017 28258421
Genetic Variation in CD36 Is Associated with Decreased Fat and Sugar Intake in Obese Children and Adolescents.

BACKGROUND/AIMS: Taste is recognized as an important predictor of food choices. Thus, polymorphisms in genes encoding taste receptors may explain the ...

Feb 25 2017 28237985
Machine learning in the prediction of cardiac epicardial and mediastinal fat volumes.

We propose a methodology to predict the cardiac epicardial and mediastinal fat volumes in computed tomography images using regression algorithms. The ...

Feb 24 2017 28318505
RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems.

We demonstrate the use of high-throughput biodosimetry platforms based on commercial high-throughput/high-content screening robotic systems. The cytok...

Feb 23 2017 28231025
An extensive analysis of various texture feature extractors to detect Diabetes Mellitus using facial specific regions.

INTRODUCTION: Researchers have recently discovered that Diabetes Mellitus can be detected through non-invasive computerized method. However, the focus...

Feb 22 2017 28237906
Automatic data source identification for clinical trial eligibility criteria resolution.

Clinical trial coordinators refer to both structured and unstructured sources of data when evaluating a subject for eligibility. While some eligibilit...

Feb 10 2017 28269912
Learning Effective Treatment Pathways for Type-2 Diabetes from a clinical data warehouse.

Treatment guidelines for management of type-2 diabetes mellitus (T2DM) are controversial because existing evidence from randomized clinical trials do ...

Feb 10 2017 28269963
Automatic diet monitoring: a review of computer vision and wearable sensor-based methods.

Food intake and eating habits have a significant impact on people's health. Widespread diseases, such as diabetes and obesity, are directly related to...

Jan 31 2017 28139173
Dermatologist-level classification of skin cancer with deep neural networks.

Skin cancer, the most common human malignancy, is primarily diagnosed visually, beginning with an initial clinical screening and followed potentially ...

Jan 25 2017 28117445
An Integrated Soft Computing Approach to Hughes Syndrome Risk Assessment.

The AntiPhospholipid Syndrome (APS) is an acquired autoimmune disorder induced by high levels of antiphospholipid antibodies that cause arterial and v...

Jan 23 2017 28116566
The Potential Therapeutic Application of Peptides and Peptidomimetics in Cardiovascular Disease.

Cardiovascular disease (CVD) remains a leading cause of mortality and morbidity worldwide. Numerous therapies are currently under investigation to imp...

Jan 6 2017 28111551
Diagnostic Method of Diabetes Based on Support Vector Machine and Tongue Images.

. The purpose of this research is to develop a diagnostic method of diabetes based on standardized tongue image using support vector machine (SVM). T...

Jan 4 2017 28133611
Effects of Ipragliflozin on Diabetic Nephropathy and Blood Pressure in Patients With Type 2 Diabetes: An Open-Label Study.

BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are novel agents used to treat type 2 diabetic patients. We investigated the efficacy of...

Dec 31 2016 28090231
Relationships among exercise capacity, dynamic balance and gait characteristics of Nigerian patients with type-2 diabetes: an indication for fall prevention.

This study investigated the relationships among exercise capacity (EC), dynamic balance (DB), and gait characteristics (GCs) of patients with type-2 d...

Dec 31 2016 28119881
Clinical features of childhood diabetes mellitus focusing on latent autoimmune diabetes.

PURPOSE: This study was designed to evaluate the clinical characteristics of childhood diabetes mellitus (DM) according to its classification as well ...

Dec 31 2016 28164074
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