Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Towards Social Good: How Can Social Media Inform the Next GenAI's Collaboration With Humans for Dietary Support?

The rapid advancement of Generative AI (GenAI) has transformed human-computer interaction, particularly in domains requiring personalized guidance, such as nutritional planning. While GenAIs show promise in generating contextual nutritional recommendations, their integration into social interactions and behavioral patterns (which are key aspects of the Internet of Behavior - IoB) remains inadequat...

May 4 2026 42666360

Non-destructive classification of type 2 diabetic teeth using LIBS-derived elemental biomarkers and machine learning.

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic metabolic illness that severely alters oral health, elevating periodontal infection incidence and dental treatment failures via mechanisms including hyperglycemia. While laser-induced breakdown spectroscopy (LIBS) using machine learning (ML) has demonstrated the presence of diabetes in hair, nails, and urine, mineralized tooth tissues that p...

May 4 2026 42191259
Neutrophil extracellular traps-related biomarkers in idiopathic pulmonary arterial hypertension: A machine learning-based identification and experimental validation study.

Neutrophil extracellular traps (NETs) are increasingly recognized as critical mediators in vascular inflammation and remodeling, yet their molecular m...

May 4 2026 42085826
Cost-effectiveness of latent tuberculosis infection screening using interferon-gamma release assays among migrants to Japan: a Markov modelling study incorporating social vulnerability and access barriers.

OBJECTIVE: This study aims to evaluate the cost-effectiveness of latent tuberculosis infection (LTBI) screening strategies using interferon-gamma rele...

May 4 2026 42082223
Understanding LUng Cancer risk factors and their Impact Assessment (LUCIA): protocol for multicentre observational cohort study.

INTRODUCTION: Lung cancer (LC) is the leading cause of cancer-related mortality worldwide, primarily due to diagnosis at advanced stages. Although low...

May 4 2026 42082236
An interpretable progressive residual network for automated multiclass diabetes diagnosis.

Diabetes mellitus remains one of the most widespread and burdensome chronic diseases worldwide, yet invasive assays and high costs constrain early det...

May 4 2026 42082595
Co-morbid biomarkers for sarcopenic obesity associated with gut microbiota metabolites: From burden to treatment.

BACKGROUND: The detrimental cycle of sarcopenic obesity (SO) significantly reduces quality of life in older adults, while the mechanisms are still unc...

May 4 2026 42081471
Development and validation of a machine learning-based screening tool for early detection of adolescent suicide risk.

BACKGROUND: Adolescent suicide remains a significant public health concern, yet existing suicide screening instruments primarily focus on already mani...

May 3 2026 42076808
AI and the digital pathology revolution: clinical applications in cancer diagnosis and assessment.

INTRODUCTION: Hematoxylin & Eosin (H&E) stained slides are the gold standard for cancer diagnosis but are subject to labor-intensive review and inter-...

May 3 2026 42070246
Auto Machine Learning for Diabetic Retinopathy Screening: A Head-to-Head Multiplatform Comparison Against Human Graders and IDx-DR.

PURPOSE: To benchmark multiple automated machine learning (AutoML) platforms for diabetic retinopathy (DR) screening from fundus photographs using a u...

May 2 2026 42082068
Ultra-low-dose CT for malignant metastasis screening using a deep learning image reconstruction algorithm.

PURPOSE: To evaluate the feasibility and diagnostic performance of ultra-low-dose CT (ULD-CT) for screening malignant metastasis using super-resolutio...

May 2 2026 42102570
Economic evaluation of artificial intelligence for cancer detection in the UK breast screening programme.

BACKGROUND: Artificial intelligence (AI) offers a potential solution to radiologist shortages in breast cancer screening while maintaining diagnostic ...

May 2 2026 42069897
Medicinal Plants and the Gastrointestinal Microbiota in Chronic Diseases Modulation: A Structured Mechanistic and Translational Review.

The gut microbiome supports digestion, immunity, and metabolism; its imbalance (dysbiosis) drives inflammation and metabolic dysfunction, contributing...

May 2 2026 42070004
Artificial intelligence on chest X-ray for tuberculosis screening in Tanzania: a multicentre evaluation.

Tanzania has adopted artificial intelligence (AI)-assisted chest X-ray screening for tuberculosis (TB), including the use of CAD4TB version 6, which i...

May 2 2026 42070033
Identification of MMP14 and FOS as key regulators of vascular smooth muscle cell senescence in diabetic kidney disease: A combined bioinformatics and experimental study.

OBJECTIVE: Diabetic kidney disease (DKD) is a leading microvascular complication of diabetes in which vascular smooth muscle cell (VSMC) senescence pl...

May 1 2026 42107160
Identification of COL5A1 and TGFBI as key basement membrane genes and their molecular mechanisms in gestational diabetes mellitus.

Gestational diabetes mellitus (GDM) is a common complication during pregnancy, but the role of the basement membrane (BM) in GDM is not well understoo...

May 1 2026 42065213
Language Equity in Pediatrics: Caring for Children From Families Who Speak a Language Other Than English.

Families who speak a language other than English (LOE) are a growing population in the United States. Children of these families are at risk of dispar...

May 1 2026 42065955
Noninvasive Screening for High-Risk Esophageal Varices in Cirrhosis: Current and Emerging Methods.

The primary goal of variceal screening in patients with cirrhosis is to identify high-risk esophageal varices (HREV) and implement preventative measur...

May 1 2026 42066054
Impact of Artificial Intelligence-Assisted Endoscopy on Screening for Upper Gastrointestinal Cancer in a Large-Scale Health Screening Facility.

OBJECTIVES: Artificial intelligence (AI)-assisted endoscopy has been developed for the early detection of upper gastrointestinal cancer; however, its ...

May 1 2026 42067512
Balancing Speed and Sensitivity: Echo-Planar Accelerated MRI for ARIA-H Screening in Anti-Aβ Therapeutics.

The recent advent of anti-amyloid-β monoclonal antibodies has introduced new demands for MRI-based screening of amyloid-related imaging abnormalities,...

May 1 2026 40820597
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