Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Showing 161-180 of 19,005 articles

Machine learning for population-level risk prediction of future cholangiocarcinoma.

BACKGROUND: The poor prognosis of cholangiocarcinoma (CCA) is largely driven by rapid, asymptomatic disease progression, which usually results in a late diagnosis in the absence of established screening strategies. An early, cost-effective, and universally applicable risk assessment strategy would therefore be valuable. METHODS: We developed machine learning (ML) models on prospective, multimodal ...

Aug 12 2026 42585990

Machine learning for thalassemia detection: A critical review of diagnostic pathways and emerging technologies.

Thalassemia is still challenging to diagnose due to heterogeneous genotypes, overlapping hematologic phenotypes (e.g., other anemias), and limited access to standardized molecular testing. Current methods of diagnosis, like complete blood count (CBC) indices, smear analysis, electrophoresis/high-performance liquid chromatography (HPLC), and targeted genetics, work effectively in the clinic. Howeve...

Aug 12 2026 42586156
Left Atrial Reservoir Strain Improves Sudden Cardiac Death Risk Stratification in Hypertrophic Cardiomyopathy.

BACKGROUND: Current risk scores for sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) have limited ability to identify high-risk subgrou...

Aug 12 2026 42586278
MINPP1, HES4 and SLCO5A1 as core signature genes mediating the effects of type 2 diabetes on coronary artery bypass grafting.

PURPOSE: This study aimed to identify the signature genes that mediate the effects of type 2 diabetes (T2D) on coronary artery bypass grafting (CABG),...

Aug 12 2026 42586373
Stephania cepharantha Hayata (Baiyaozi) attenuates cirrhosis-associated intestinal barrier injury by restoring mitochondrial function and suppressing PI3K/AKT signaling.

ETHNOPHARMACOLOGICAL RELEVANCE: Baiyaozi, the dried tuberous root of Stephania cepharantha Hayata, has long been used in traditional Chinese medicine ...

Aug 12 2026 42586397
Automated Vocal Fatigue Screening in Professional Voice Users: Development and Occupational Validation of an Automated Assessment System.

INTRODUCTION: Professional voice users face an elevated risk of vocal injury from sustained occupational voice use, yet scalable tools for workplace s...

Aug 12 2026 42586866
A benchmarking study of feature screening approaches across type 1 diabetes omics studies classification settings.

In recent years, high dimensional omics analyses have become more commonplace for investigating complex biological systems. Typically, these studies a...

Aug 12 2026 42585225
Explainable machine learning for predicting childhood anemia in Sub-Saharan Africa using population-based DHS Data (2016-2024).

Childhood anemia remains a major public health challenge in Sub-Saharan Africa, adversely affecting physical growth, cognitive development, and child ...

Aug 12 2026 42585217
Identification of critical brain regions for young adults with obesity and their relationships with impulsivity using machine learning based on neuroanatomical features.

BACKGROUND: Prior obesity neuroimaging studies used univariate methods and small samples, limiting reproducibility. Employing a large-scale dataset an...

Aug 11 2026 42581075
A scoping review on the application of new technology in the screening and diagnosis of adolescent idiopathic scoliosis.

INTRODUCTION: Adolescent Idiopathic Scoliosis (AIS) affects 2-4% of adolescents globally. Current screening methods face challenges, including high fa...

Aug 11 2026 42581262
Predictive Modelling of 3-Month Glycemic Target Achievement in Type 2 Diabetes Mellitus Using Artificial Intelligence and Continuous Glucose Monitoring: A Retrospective Cohort Study.

AIMS: To develop and validate a machine learning model incorporating continuous glucose monitoring (CGM) metrics to predict 3-month glycemic target ac...

Aug 11 2026 42581435
Accuracy of Chatbot-Based Health Advice Related to Traumatic Dental Injuries: A Systematic Review and Meta-Analysis.

BACKGROUND/AIMS: The growing use of generative artificial intelligence, especially chatbots, has motivated researchers to test the accuracy of health ...

Aug 11 2026 42581485
Diagnostic decision-making, vertebral augmentation, and osteoporosis therapy in vertebral compression fractures: a narrative review.

Vertebral compression fractures (VCFs) represent the most prevalent osteoporotic fracture and constitute a growing cause of morbidity, mortality, and ...

Aug 11 2026 42576288
Bridging the Diagnostic Gap: Reviewing Current Endometriosis Screening Tools and Models.

Background: Endometriosis affects 10% of reproductive-aged women globally and is one of the major causes of infertility. It is a debilitating, chronic...

Aug 11 2026 42576664
Opportunistic Screening for Chagas Disease Using an Artificial Intelligence-Enabled ECG: Prospective Evaluation of Feasibility and Diagnostic Accuracy.

BACKGROUND: Chagas disease (ChD), a neglected cardiovascular condition, affects 7.5 to 10.5 million people worldwide. Opportunistic screening during r...

Aug 11 2026 42576808
The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning.

BACKGROUND: Risk prediction is fundamental to pulmonary hypertension (PH) guideline-based care, yet pediatric-specific risk prediction models remain l...

Aug 11 2026 42576812
Innovations using digital technologies for periodontal diagnosis and prognosis: a narrative review.

OBJECTIVE: This narrative review aims to identify and evaluate the available scientific literature on digital technologies assisting clinicians in per...

Aug 11 2026 42578725
Mass Spectrometry Prediction Based on Few-Shot Neural Network and Chemical Prior Knowledge for Regulatory Screening of Cosmetic Glucocorticoid.

Glucocorticoids are prohibited in cosmetics due to health risks, yet illegal additions persist through structural modifications that evade conventiona...

Aug 11 2026 42578841
Research trends and hotspots in robot-assisted ophthalmic surgery: a bibliometric and visualization study.

Robot-assisted ophthalmic surgery has undergone rapid development in recent decades. Robot-assisted ophthalmic surgery, as examined through bibliometr...

Aug 11 2026 42579049
Artificial intelligence, surgical vision, and digital navigation in robotic urology: a bibliometric and knowledge-mapping analysis.

Digital technologies are increasingly used to extend the anatomical, functional, and procedural information available in robot-assisted urology, but t...

Aug 11 2026 42579258
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