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Predicting Post-Traumatic Epilepsy from Clinical Records using Large Language Model Embeddings

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and reliance on resource-intensive neuroimaging data. We investigate whether routinely collected acute clinical records alone can support early PTE prediction using ...

Apr 16 2026 2604.14547v1

Can LLMs Score Medical Diagnoses and Clinical Reasoning as well as Expert Panels?

Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators. Here, we evaluate an LLM jury composed of three frontier AI models scoring 3333 diagnoses on 300 real-world middle-income country (MIC) hospital cases. Model performance was benchmarked against expert clinician panel and independent human r...

Apr 16 2026 2604.14892v1
Neural mechanism of postural sway-related beta-band oscillations: a cortico-basal ganglia-thalamic network model of intermittent control

Recent EEG studies of human quiet stance have identified beta-band event-related desynchronization (beta-ERD) and synchronization (beta-ERS; post-move...

SOAR: Self-Correction for Optimal Alignment and Refinement in Diffusion Models

The post-training pipeline for diffusion models currently has two stages: supervised fine-tuning (SFT) on curated data and reinforcement learning (RL)...

Apr 14 2026 2604.12617v1
Virtual Spectral Decomposition with Dendritic Tile Selection: An Explainable AI Framework for Multimodal Tissue Composition Analysis and Immune Phenotyping Across Pancreatic, Lung, and Breast Cancer

Background: Current deep learning models in computational pathology, radiology, and digital pathology produce opaque predictions that lack the explain...

Identification and Analysis of Novel RNA Editing Sites in Neurodegenerative Diseases Using Machine Learning Approaches.

ABSTRACT Background: RNA editing is a post-transcriptional modification that alters the sequence of an RNA transcript. Two types of RNA editing were f...

Beyond Fixed False Discovery Rates: Post-Hoc Conformal Selection with E-Variables

Conformal selection (CS) uses calibration data to identify test inputs whose unobserved outcomes are likely to satisfy a pre-specified minimal quality...

Apr 13 2026 2604.11305v1
Continuous Adversarial Flow Models

We propose continuous adversarial flow models, a type of continuous-time flow model trained with an adversarial objective. Unlike flow matching, which...

Apr 13 2026 2604.11521v1
Budget-Aware Uncertainty for Radiotherapy Segmentation QA Using nnU-Net

Accurate delineation of the Clinical Target Volume (CTV) is essential for radiotherapy planning, yet remains time-consuming and difficult to assess, e...

Apr 13 2026 2604.11798v1
CatalogStitch: Dimension-Aware and Occlusion-Preserving Object Compositing for Catalog Image Generation

Generative object compositing methods have shown remarkable ability to seamlessly insert objects into scenes. However, when applied to real-world cata...

Apr 10 2026 2604.08836v1
CLIP-Inspector: Model-Level Backdoor Detection for Prompt-Tuned CLIP via OOD Trigger Inversion

Organisations with limited data and computational resources increasingly outsource model training to Machine Learning as a Service (MLaaS) providers, ...

Apr 10 2026 2604.09101v1
Weight Group-wise Post-Training Quantization for Medical Foundation Model

Foundation models have achieved remarkable results in medical image analysis. However, its large network architecture and high computational complexit...

Apr 9 2026 2604.07674v1
IatroBench: Pre-Registered Evidence of Iatrogenic Harm from AI Safety Measures

Ask a frontier model how to taper six milligrams of alprazolam (psychiatrist retired, ten days of pills left, abrupt cessation causes seizures) and it...

Apr 9 2026 2604.07709v1
FlowGuard: Towards Lightweight In-Generation Safety Detection for Diffusion Models via Linear Latent Decoding

Diffusion-based image generation models have advanced rapidly but pose a safety risk due to their potential to generate Not-Safe-For-Work (NSFW) conte...

Apr 9 2026 2604.07879v1
VDPP: Video Depth Post-Processing for Speed and Scalability

Video depth estimation is essential for providing 3D scene structure in applications ranging from autonomous driving to mixed reality. Current end-to-...

Apr 8 2026 2604.06665v1
Untargeted analysis of volatile markers of post-exercise fat oxidation in exhaled breath

Breath acetone represents a promising non-invasive biomarker for monitoring fat oxidation during exercise. However, its utility is limited by confound...

Apr 7 2026 2604.05707v1
Cardiovascular Adverse Events After Definitive Chemoradiotherapy for Lung Cancer in an Appalachian Population: Incidence and Machine Learning Based Prediction

Background Cardiovascular adverse events (CVAEs) after chemoradiotherapy (CRT) for lung cancer are major concerns in Appalachia due to high rates of s...

Overconfidence and Calibration in Medical VQA: Empirical Findings and Hallucination-Aware Mitigation

As vision-language models (VLMs) are increasingly deployed in clinical decision support, more than accuracy is required: knowing when to trust their p...

Apr 2 2026 2604.02543v1
Label Shift Estimation With Incremental Prior Update

An assumption often made in supervised learning is that the training and testing sets have the same label distribution. However, in real-life scenario...

Apr 2 2026 2604.01651v1
Governance, Accountability and Post-Deployment Monitoring Preferences for AI Integration in West African Clinical Practice: A Mixed-Methods Study

Background: The integration of artificial intelligence (AI) into clinical practice holds transformative potential for healthcare in West Africa, but s...

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