Infectious Disease

Public Health

Latest AI and machine learning research in public health for healthcare professionals.

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Easy and Fast Discrimination of Female Sand Flies from Species with Infrared Spectroscopy and Multivariate Analysis.

Accurate identification of sandfly species is critical for controlling and preventing the spread of visceral leishmaniasis, a major public health concern in Latin America. Morphological similarities between female and present a significant challenge for traditional identification methods, highlighting the need for innovative alternative approaches. This study evaluates the potential of Fourier t...

May 26 2025 40420532

Leveraging pre-vaccination antibody titres across multiple influenza H3N2 variants to forecast the post-vaccination response.

BACKGROUND: Despite decades of research on the influenza virus, we still lack a predictive understanding of how vaccination reshapes each person's antibody response, which impedes efforts to design better vaccines. Models using pre-vaccination antibody haemagglutination inhibition (HAI) titres against the vaccine strain alone poorly predict post-vaccination responses.

May 26 2025 40424667
Multi-Omics Analysis of the virulence factors and designing of next-generation multi-epitopes Vaccines against Rickettsia prowazekii: a computer-aided vaccine designing approach.

Rickettsia is a genus of bacteria that are obligate intracellular parasites and are responsible for the febrile diseases known collectively as Rickett...

May 26 2025 40418389
In-silico evaluation of Azadirachta indica-derived Daucosterol against key viral proteins of Ebolavirus using ML and MD simulations approach.

Ebola virus disease (EVD) is an acute life-threatening disease caused by highly pathogenic Ebolavirus (EBOV), with reported case fatality rates reachi...

May 26 2025 40419736
Messenger Ribonucleic Acid (mRNA)-Based Universal Vaccines: Engineering Broad-Spectrum Immunity Against Future Pandemics.

The rapid emergence and evolution of infectious pathogens, including the COVID-19 pandemic and recurring influenza outbreaks, underscore the need for ...

May 26 2025 40420966
Predicting the Activity Level of the Great Gerbil () via Machine Learning.

The great gerbil () is a pest rodent that is widely distributed in Eurasia, and assessing its outbreak risk and instituting timely population control ...

May 26 2025 40421069
Epidemiology and survival of patients with primary lymphoma of bone: a large retrospective cohort study.

Primary lymphoma of bone (PLB) is a rare extranodal lymphoma, and its epidemiology and prognosis remain controversial. We conducted a retrospective an...

May 24 2025 40411599
Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos.

Over the past few decades, the rising burden of metabolic disease, including type 2 diabetes, prediabetes, obesity, and metabolic dysfunction-associat...

May 22 2025 40403106
Remote sensing-based detection of brown spot needle blight: a comprehensive review, and future directions.

Pine forests are increasingly threatened by needle diseases, including Brown Spot Needle Blight (BSNB), caused by . BSNB leads to needle loss, reduced...

May 22 2025 40416626
Advances in Wastewater-Based Epidemiology for Pandemic Surveillance: Methodological Frameworks and Future Perspectives.

Wastewater-based epidemiology (WBE) has emerged as a transformative approach for community-level health monitoring, particularly during the COVID-19 p...

May 21 2025 40431340
Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy.

Oncolytic vaccinia viruses armed with interleukins represent a promising frontier in tumor therapy. Oncolytic vaccinia viruses express IL-2, IL-10, IL...

May 21 2025 40469178
Climate crossroads: How global warming drives coronavirus emergence, the long COVID crisis of tomorrow, and AI's role in navigating our future.

This narrative review examines the critical nexus between climate change, coronavirus emergence, and Long COVID-a triad that may shape public health o...

May 17 2025 40389117
The Impact of Biometric Surveillance on Reducing Violent Crime: Strategies for Apprehending Criminals While Protecting the Innocent.

In the rapidly evolving landscape of biometric technologies, integrating artificial intelligence (AI) and predictive analytics offers promising opport...

May 17 2025 40431950
Celluloepidemiology-A paradigm for quantifying infectious disease dynamics on a population level.

To complement serology as a tool in public health interventions, we introduced the "celluloepidemiology" paradigm where we leveraged pathogen-specific...

May 16 2025 40378227
AI-Enabled Diagnostic Prediction within Electronic Health Records to Enhance Biosurveillance and Early Outbreak Detection.

Detecting infectious disease outbreaks promptly is crucial for effective public health responses, minimizing transmission, and enabling critical inter...

May 16 2025 40463569
Multi-criteria decision making and its application to in silico discovery of vaccine candidates for Toxoplasma gondii.

Vaccine discovery against eukaryotic parasites is not trivial and few exist. Reverse vaccinology is an in silico vaccine discovery approach, designed ...

May 15 2025 40378548
Polyanhydride-Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single-Injection Self-Boosting Vaccines.

Vaccination remains a critical tool in preventing infectious diseases, yet its effectiveness is undermined by under-immunization, particularly for vac...

May 15 2025 40370205
SARS-CoV-2: lessons in virus mutation prediction and pandemic preparedness.

The COVID-19 pandemic has prompted an unprecedented global response. In particular, extraordinary efforts have been dedicated toward monitoring and pr...

May 15 2025 40378522
Surveillance of SARS-CoV-2 RNA in wastewater treatment plants in Türkiye, Istanbul: a long-term study and statistical analysis.

Wastewater-based epidemiology (WBE) is a powerful method that allows community surveillance to identify diseases/pandemic dynamics in a city, especial...

May 12 2025 40353924
Assessment of the transmission of live-attenuated chikungunya virus vaccine VLA1553 by Aedes albopictus mosquitoes.

BACKGROUND: Chikungunya virus (CHIKV) is a mosquito-transmitted, arthritogenic alphavirus that causes sporadic outbreaks of often debilitating rheumat...

May 12 2025 40355954
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