Public Health

Anti-HBs persistence and anamnestic response among medical interns vaccinated in infancy.

Medical interns are at high risk of acquiring Hepatitis B Virus (HBV) infection during their training. HBV vaccination is the most effective measure to reduce the global incidence of HBV. The duration of protection after HBV vaccination is still controversial. We aimed to determine the prevalence of protective anti-HBs levels among medical interns who had received compulsory hepatitis B vaccinatio...

A Review of Cross-Species Transmission Mechanisms of Influenza Viruses.

The cross-species transmission of influenza viruses represents a critical link in the pandemic of zoonotic diseases. This mechanism involves multi-level interactions, including viral genetic adaptability, host-receptor compatibility, and ecological drivers. Recent studies have highlighted the essential role of mutations in hemagglutinin and neuraminidase in overcoming host barriers, while elucidat...

Leafing a mark on immunity: Quercetin-3-O-D-glucopyranoside and quercetin-3-O-(2″,6″-digalloyl)-β-D-galactopyranoside-rich Melia azedarach L. extract's immunoinflammatory effects on an sRBC-immunized BALB/c model.

Melia azedarach L. (Meliaceae) (MA) leaves are traditionally used for inflammatory disorders, yet their immunomodulatory effects on lymphocytes remain...

Development and Clinical Evaluation of a Mpox Antigen-detecting Rapid Diagnostic Test.

To address the global emergence of mpox after the 2022 epidemic, a rapid and accurate diagnostic tool is needed at the point of care to identify indiv...

Technical validation of a multiplex real-time PCR for combined detection of Rift Valley fever, chikungunya, Zika and dengue viruses.

Several arthropod-borne (arbo)-viruses have overlapping symptoms, insect vectors and geographical occurrence. With little known about the importance o...

Challenges on the implementation of wastewater-based epidemiology as a prediction tool: the paradigm of SARS-CoV-2.

Wastewater Based Epidemiology (WBE) has been identified as a tool for monitoring and predicting patterns of SARS-CoV-2 in communities. Several factors...

Serum Vitamin D and the Risk of SARS-CoV-2 and Seasonal Influenza Infection During the Twindemic Period.

BACKGROUND & AIMS: The association between circulating vitamin D levels and the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) o...

Neural networks to model COVID-19 dynamics and allocate healthcare resources.

This study presents a neural network-based framework for COVID-19 transmission prediction and healthcare resource optimization. The model achieves hig...

Global burden of non-melanoma skin cancers among older adults: a comprehensive analysis using machine learning approaches.

Non-melanoma skin cancers (NMSCs), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), have shown significant global increases in ...

A digital photography dataset for Vaccinia Virus plaque quantification using Deep Learning.

Virological plaque assay is the major method of detecting and quantifying infectious viruses in research and diagnostic samples. Furthermore, viral pl...

A simple yet effective approach for predicting disease spread using mathematically-inspired diffusion-informed neural networks.

The COVID-19 outbreak has highlighted the importance of mathematical epidemic models like the Susceptible-Infected-Recovered (SIR) model, for understa...

Multifractal analysis and support vector machine for the classification of coronaviruses and SARS-CoV-2 variants.

This study presents a novel approach for the classification of coronavirus species and variants of SARS-CoV-2 using Chaos Game Representation (CGR) an...

Introduction to WBE case estimation: A practical toolset for public health practitioners.

Public health practitioners can use wastewater data to grasp disease dynamics, including incidence, prevalence, and potential disease trajectory. The ...

Pathogenicity and virulence of lumpy skin disease virus: A comprehensive update.

Lumpy skin disease (LSD), which was confined to the Africa for many decades, has expanded its geographical distribution to numerous countries across A...

A robotic rehabilitation intervention in a home setting during the Covid-19 outbreak: a feasibility pilot study in patients with stroke.

BACKGROUND: Telerehabilitation allows patients to engage in therapy away from healthcare facilities, often in the comfort of their homes. Studies have...

Role of artificial intelligence in advancing immunology.

Artificial intelligence (AI) has revolutionized various biomedical fields, particularly immunology, by enhancing vaccine development, immunotherapies,...

Exploring the potential and limitations of deep learning and explainable AI for longitudinal life course analysis.

BACKGROUND: Understanding the complex interplay between life course exposures, such as adverse childhood experiences and environmental factors, and di...

Data-driven survival modeling for breast cancer prognostics: A comparative study with machine learning and traditional survival modeling methods.

Background This investigation delves into the potential application of data-driven survival modeling approaches for prognostic assessments of breast c...

Detection and prevalence of avian influenza epidemic in the southwest of Poyang Lake and analysis of the influence of meteorological factors.

Recently, the epidemiological profile of avian influenza has changed dramatically worldwide. Avian influenza sampling and surveillance of wholesale an...

Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning.

The design of proteins capable effectively binding to specific protein targets is crucial for developing therapies, diagnostics, and vaccine candidate...