Pulmonology

Respiratory gas exchange during robotic-assisted laparoscopic radical prostatectomy.

STUDY OBJECTIVE: Robotic-assisted laparoscopic prostatectomy requires patients to be secured in a steep Trendelenburg position for several hours. Added to the CO2 pneumoperitoneum that is created, this positioning invariably restricts diaphragmatic and chest wall excursion, which can adversely affect respiratory gas exchange. This study sought to measure the extent of respiratory gas change during...

A tuberculosis ontology for host systems biology.

A major hurdle facing tuberculosis (TB) investigators who want to utilize a rapidly growing body of data from both systems biology approaches and omics technologies is the lack of a standard vocabulary for data annotation and reporting. Lacking a means to readily compare samples from different research groups, a significant quantity of potentially informative data is largely ignored by researchers...

Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads.

BACKGROUND: A concentration of specimen is recommended for the effective recovery of Mycobacterium tuberculosis (MTB), but the bacteriological efficie...

RAIRS2 a new expert system for diagnosing tuberculosis with real-world tournament selection mechanism inside artificial immune recognition system.

Tuberculosis is a major global health problem that has been ranked as the second leading cause of death from an infectious disease worldwide, after th...

Differential diagnosis of pleural mesothelioma using Logic Learning Machine.

BACKGROUND: Tumour markers are standard tools for the differential diagnosis of cancer. However, the occurrence of nonspecific symptoms and different ...

Robotic ablation of atrial fibrillation.

BACKGROUND: Pulmonary vein isolation (PVI) is an established treatment for atrial fibrillation (AF). During PVI an electrical conduction block between...

Comparison of Coopdech®, CoPilot®, Intubrite®, and Macintosh laryngoscopes for tracheal intubation during pediatric cardiopulmonary resuscitation: a randomized, controlled crossover simulation trial.

UNLABELLED: The aim of the study was to compare the intubation times and success rates of various laryngoscopes during resuscitation in pediatric emer...

Bioinformatics approach reveals systematic mechanism underlying lung adenocarcinoma.

BACKGROUND: The purpose of this work was to explore the systematic molecular mechanism of lung adenocarcinoma and gain a deeper insight into it.

Classification of usual interstitial pneumonia in patients with interstitial lung disease: assessment of a machine learning approach using high-dimensional transcriptional data.

BACKGROUND: Idiopathic pulmonary fibrosis is a progressive fibrotic lung disease that distorts pulmonary architecture, leading to hypoxia, respiratory...

Cancer adjuvant chemotherapy strategic classification by artificial neural network with gene expression data: An example for non-small cell lung cancer.

PURPOSE: Adjuvant chemotherapy (ACT) is used after surgery to prevent recurrence or metastases. However, ACT for non-small cell lung cancer (NSCLC) is...

A hybrid method for airway segmentation and automated measurement of bronchial wall thickness on CT.

Inflammatory and infectious lung diseases commonly involve bronchial airway structures and morphology, and these abnormalities are often analyzed non-...

Application of an artificial neural network model for selection of potential lung cancer biomarkers.

Determination of volatile organic compounds (VOCs) in the exhaled breath samples of lung cancer patients and healthy controls was carried out by SPME-...

Clinical evaluation of postoperative chemotherapy based on genetic testing in patients with stage IIIA non-small cell lung cancer.

BACKGROUND: We performed a retrospective analysis to evaluate whether a postoperative chemotherapy selection method based on four tumoral gene express...

Hemoglobin-based oxygen carriers promote systemic hyperfibrinolysis that is both dependent and independent of plasmin.

BACKGROUND: Hyperfibrinolysis plays an integral role in the genesis of trauma-induced coagulopathy. Recent data demonstrate that red blood cell lysis ...

Computer-aided lung nodule recognition by SVM classifier based on combination of random undersampling and SMOTE.

In lung cancer computer-aided detection/diagnosis (CAD) systems, classification of regions of interest (ROI) is often used to detect/diagnose lung nod...

A fast neural network approach to predict lung tumor motion during respiration for radiation therapy applications.

During radiotherapy treatment for thoracic and abdomen cancers, for example, lung cancers, respiratory motion moves the target tumor and thus badly af...

Locality-constrained Subcluster Representation Ensemble for lung image classification.

In this paper, we propose a new Locality-constrained Subcluster Representation Ensemble (LSRE) model, to classify high-resolution computed tomography ...

An open-label, in-use study assessing the warming sensation accompanying IFF Flavour 316282 and the acceptability and local tolerability of a syrup containing paracetamol and pseudoephedrine for the short-term treatment of symptoms of an upper respiratory tract infection.

OBJECTIVE: The primary objective was to assess the warming sensation caused by IFF Flavour 316282 in a syrup used for short-term treatment by patients...

Prediction of cancer proteins by integrating protein interaction, domain frequency, and domain interaction data using machine learning algorithms.

Many proteins are known to be associated with cancer diseases. It is quite often that their precise functional role in disease pathogenesis remains un...

Correlation of plasma crizotinib trough concentration with adverse events in patients with anaplastic lymphoma kinase positive non-small-cell lung cancer.

BACKGROUND: Crizotinib, an ATP-competitive receptor tyrosine kinase inhibitor of both anaplastic lymphoma kinase (ALK) and the hepatocyte growth facto...