Psychiatry

Schizophrenia

Latest AI and machine learning research in schizophrenia for healthcare professionals.

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Chatbot relational dependence and psychosis risk: Conversational artificial intelligence as a potential behavioral addiction context.

Conversational artificial intelligence (AI) chatbots are increasingly used for emotional support, companionship, and psychological reflection. Their capacity to simulate attentiveness, empathy, and conversational continuity may shift technology use from instrumental interaction toward relational engagement. Emerging clinical observations suggest that intensive chatbot use may, in vulnerable indivi...

May 18 2026 42149657

Aging beyond diagnosis: the MRI brain age gap across disorders.

The brain age gap (BAG), the difference between magnetic resonance imaging-predicted brain age and chronological age, is a proposed marker of neurobiological aging, yet its transdiagnostic significance remains uncertain. This meta-analysis evaluated BAG in Alzheimer's disease (AD), mild cognitive impairment (MCI), multiple sclerosis (MS), Parkinson's disease (PD), schizophrenia (SCZ), stroke, and ...

May 16 2026 42142219
Multi-objective optimization in population pharmacokinetic model selection and optimization: application of NSGA-II in pyDarwin.

The selection of a "good" model usually involves a combination of objective and subjective criteria. Although many aspects of model quality can be exp...

May 16 2026 42143189
Accuracy and hallucination behaviors of artificial intelligence-based large language models for dental implant identification on radiographs.

OBJECTIVES: This study aimed to evaluate the accuracy and error patterns of four artificial intelligence-based large language models (LLMs) in identif...

May 15 2026 42142612
Machine learning-based integration identifies a 10-gene predictive signature and its classification patterns in schizophrenia.

BACKGROUND: Schizophrenia (SCZ) is a highly heritability psychological disorder, however the exact etiology remains unclear, and lack of the reliable ...

May 14 2026 42133007
Cross-Dataset Evaluation of an Automated Video-Based Model for Detecting Tardive Dyskinesia Using the Clinician's Tardive Inventory: Validation Study.

BACKGROUND: Tardive dyskinesia (TD) is a common, often underrecognized movement disorder resulting from long-term antipsychotic use, yet its detection...

May 14 2026 42133936
Diagnostic accuracy and citation integrity of four large language models on otolaryngology vignettes.

OBJECTIVES: This study aimed to compare the diagnostic accuracy and citation integrity of four large language models (LLMs) including one general (Cha...

May 13 2026 42120572
Adaptive drift-aware multi-stage deep learning framework for EEG-based schizophrenia diagnosis.

This study introduces a novel adaptive deep learning framework for EEG-based schizophrenia diagnosis that addresses the limitations of existing static...

May 11 2026 42116189
Use of Generative Artificial Intelligence in the Management of Low Back Pain: a Scoping Review.

BACKGROUND CONTEXT: Low back pain (LBP) is common and a major cause of disability globally. Generative artificial intelligence (GenAI) such as ChatGPT...

May 9 2026 42105128
Digital phenotyping for predicting relapse in psychiatric disorders: a systematic review of passive sensing approaches.

BACKGROUND: Digital phenotyping - the moment-by-moment quantification of individual-level human behavior using data from personal digital devices - of...

May 9 2026 42106724
Cognitive Function Assessment Using a Virtual Reality Serious Game System in Patients With Stable Schizophrenia: Prospective Cohort Study.

BACKGROUND: Cognitive impairment is a core and enduring deficit in schizophrenia, severely affecting social functioning and quality of life. Tradition...

May 8 2026 42102386
Clinical and quality of life predictors in patients with schizophrenia with and without substance use disorder.

The comorbidity of schizophrenia (SZ) and substance use disorder (SUD), also known as dual schizophrenia (SZ+), represents a clinical challenge due to...

May 7 2026 42105999
Global Perspectives on CNS Drug Innovation: Achievements, Barriers, and Priorities for the Next Decade.

BACKGROUND: Over the past decade, neuropsychopharmacology has shifted from stagnation to momentum, with first-in-class mechanisms and biomarker-enable...

May 7 2026 42096531
Smartphone gaze-tracking for accessible psychiatric assessment.

Eye movements are promising biomarkers for psychiatric and neurological disorders, yet conventional recording methods rely on bulky, expensive, and la...

May 5 2026 42086860
Revisiting Out-of-Distribution Detection in Real-Time Object Detection: From Benchmark Pitfalls to a New Mitigation Paradigm.

Out-of-distribution (OoD) inputs pose a persistent challenge to deep learning models, often triggering overconfident predictions on non-target objects...

May 1 2026 41489965
Channel Graph Neural Network Revealing Multimodal Brain Connectivity Abnormalities in Schizophrenia.

Investigating abnormal brain network characteristics in schizophrenia can improve our understanding of disease mechanisms and help identify potential ...

May 1 2026 41732835
Fingerprints Encode Risk for Bipolarity.

BACKGROUND: Fingerprint patterns are developed during pregnancy and share a common embryogenic origin with the central nervous system. Considering the...

May 1 2026 41792879
Association-sensory spatiotemporal hierarchy and functional gradient-regularised recurrent neural network with implications for schizophrenia.

The human neocortex is functionally organised at its highest level along a continuous sensory-to-association (AS) hierarchy. This study investigates t...

Apr 30 2026 42056136
Psychiatric Risk Associated With Large Language Model Chatbots: An Emerging Concern.

Large language model chatbots such as ChatGPT have been adopted by millions of users, yet their psychiatric implications are poorly understood. Recent...

Apr 29 2026 42050395
A multi-target drug design method based on target feature fusion.

BACKGROUND: Targeted drugs are medications designed to treat diseases by targeting specific sites on cancerous or diseased cells. Multi-target drugs c...

Apr 29 2026 42050404
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