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Steroids

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Development and validation of explainable machine learning models for female hip osteoporosis using electronic health records.

BACKGROUND: Hip fractures are associated with reduced mobility, and higher morbidity, mortality, and...

Jul 2025 40132236
Predicting treatment outcome in congenital adrenal hyperplasia using urine steroidomics and machine learning.

OBJECTIVE: Treatment monitoring of individuals with congenital adrenal hyperplasia (CAH) remains uns...

Jun 2025 40515610
Opportunistic Osteoporosis Diagnosis via Texture-Preserving Self-Supervision, Mixture of Experts and Multi-Task Integration

Osteoporosis, characterized by reduced bone mineral density (BMD) and compromised bone microstruct...

A flexible machine learning Mendelian randomization estimator applied to predict the safety and efficacy of sclerostin inhibition.

Mendelian randomization (MR) enables the estimation of causal effects while controlling for unmeasur...

Jun 2025 40378846
Manipulating 3D Molecules in a Fixed-Dimensional SE(3)-Equivariant Latent Space

Medicinal chemists often optimize drugs considering their 3D structures and designing structurally...

Enhancing osteoporosis risk prediction using machine learning: A holistic approach integrating biomarkers and clinical data.

Osteoporosis (OP) affects approximately 18 % of the global population, with osteoporosis-associated ...

Jun 2025 40328025
Using Machine Learning to Identify Predictors of Maternal and Infant Hair Cortisol Concentration Before and During the COVID-19 Pandemic.

Hair cortisol concentration (HCC) has been theorized to reflect chronic stress, and maternal and inf...

Jun 2025 40444444
Predicting the solubility of drugs in supercritical carbon dioxide using machine learning and atomic contribution.

The pharmaceutical sector is aware of supercritical CO (SC-CO) as a possible replacement for problem...

Jun 2025 40250491
A machine learning-derived angiogenesis signature for clinical prognosis and immunotherapy guidance in colon adenocarcinoma.

Colon adenocarcinoma (COAD) is one of the most prevalent malignancies worldwide and its prognosis is...

May 2025 40450107
Application of machine learning algorithms in osteoporosis analysis based on cardiovascular health assessed by life's essential 8: a cross-sectional study.

BACKGROUND: Life's Essential 8 (LE8) for assessing cardiovascular health (CVH) has been demonstrated...

May 2025 40442859
Comparative Analysis of Feature Extraction Methods and Machine Learning Models for Predicting Osteoporosis Prevalence.

This study systematically examined the impact of three feature selection techniques (Boruta, Extreme...

May 2025 40439990
Deep Learning-Based BMD Estimation from Radiographs with Conformal Uncertainty Quantification

Limited DXA access hinders osteoporosis screening. This proof-of-concept study proposes using wide...

Molecular Insights into the Binding of Organophosphate Flame Retardant Key Metabolites with Mineralocorticoid and Estrogen Receptors.

Flame retardants (FR) encompass a wide range of chemicals designed to inhibit and reduce the spread ...

May 2025 40415815
Total radius BMD correlates with the hip and lumbar spine BMD among post-menopausal patients with fragility wrist fracture in a machine learning model.

UNLABELLED: Osteoporosis screening should be systematic in the group of over 50-year-old females wit...

May 2025 40366492
Severe community-acquired pneumonia (sCAP): advances in management and future directions.

Severe community-acquired pneumonia (sCAP) is a major global health challenge, with high morbidity a...

May 2025 40360263
Multicenter target trial emulation to evaluate corticosteroids for sepsis stratified by predicted organ dysfunction trajectory.

Corticosteroids decrease the duration of organ dysfunction in sepsis and a range of overlapping and ...

May 2025 40360520
Identifying Mild-to-Moderate Atopic Dermatitis Using a Generic Machine Learning Approach: A Danish National Health Register Study.

Atopic dermatitis is a chronic skin disease, causing itching and recurrent eczematous lesions. In Da...

May 2025 40364476
Cost-effectiveness of opportunistic osteoporosis screening using chest radiographs with deep learning in Germany.

BACKGROUND: Osteoporosis is often underdiagnosed due to limitations in traditional screening methods...

May 2025 40355760
AI-Enabled Exoskeletal Robotics for Enhancing Mobility, Bone Regeneration, and Functional Rehabilitation in Osteoporosis: A Literature Review.

The care of osteoporosis is being revolutionized by developments in AI-enabled exoskeletal robotics,...

May 2025 40357605
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