Endocrinology

Steroids

Latest AI and machine learning research in steroids for healthcare professionals.

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Cost-effectiveness of opportunistic osteoporosis screening using chest radiographs with deep learning in Germany.

BACKGROUND: Osteoporosis is often underdiagnosed due to limitations in traditional screening methods, leading to missed early intervention opportunities. AI-driven screening using chest radiographs could improve early detection, reduce fracture risk, and improve public health outcomes.

May 13 2025 40355760

AI-Enabled Exoskeletal Robotics for Enhancing Mobility, Bone Regeneration, and Functional Rehabilitation in Osteoporosis: A Literature Review.

The care of osteoporosis is being revolutionized by developments in AI-enabled exoskeletal robotics, which can improve mobility and facilitate the recovery from fragility fractures. The literature on current advancements in exoskeletal robotics and their therapeutic implications for patients with osteoporosis with particular attention paid to investigations on bone regeneration, functional rehabil...

May 12 2025 40357605
Fusogenic Lipid Nanovesicles as Multifunctional Immunomodulatory Platforms for Precision Solid Tumor Therapy.

Although immunotherapy demonstrates considerable prospect in overcoming solid tumors, its clinical efficacy is limited by several factors, such as poo...

May 12 2025 40351077
Dendritic cell-based microrobots for enhanced systemic antigen-specific immune tolerance.

Current immunotherapeutic approaches for autoimmune disorders primarily rely on the use of generalized immunosuppressive medications. However, most im...

May 10 2025 40010412
Revisiting the role of steroidal therapeutics in the 21st century: an update on FDA approved steroidal drugs (2000-2024).

Steroids are biologically active polycyclic compounds that have garnered significant scientific attention due to their distinct physiochemical propert...

May 8 2025 40352672
Accuracy of Low-Dose Chest CT-Based Artificial Intelligence Models in Osteoporosis Detection: A Systematic Review and Meta-analysis.

The purpose of this study is to systematically review and evaluate the accuracy of low-dose chest CT-based artificial intelligence in osteoporosis scr...

May 2 2025 40314789
Machine Learning Meets Transparency in Osteoporosis Risk Assessment: A Comparative Study of ML and Explainability Analysis

The present research tackles the difficulty of predicting osteoporosis risk via machine learning (ML) approaches, emphasizing the use of explainable...

LC-MS/MS-Based Assay for Steroid Profiling in Peripheral and Adrenal Venous Samples for the Subtyping of Primary Aldosteronism.

Given the largely unexplored application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) steroid analysis in primary aldosteronism (PA), ...

May 1 2025 40346860
Deep Learning Technique for Automatic Segmentation of Proximal Hip Musculoskeletal Tissues From CT Scan Images: A MrOS Study.

BACKGROUND: Age-related conditions, such as osteoporosis and sarcopenia, alongside chronic diseases, can result in significant musculoskeletal tissue ...

Apr 1 2025 40022453
A Multi-Site Study on AI-Driven Pathology Detection and Osteoarthritis Grading from Knee X-Ray

Introduction: Bone health disorders like osteoarthritis and osteoporosis pose major global health challenges, often leading to delayed diagnoses due...

A Deep Learning Model for Three-Dimensional Determination of Whole Thoracic Vertebral Bone Mineral Density from Noncontrast Chest CT: The Multi-Ethnic Study of Atherosclerosis.

Background Recent studies have investigated how deep learning (DL) algorithms applied to CT using two-dimensional (2D) segmentation (sagittal or axial...

Mar 1 2025 40067103
EXACT-CT: EXplainable Analysis for Crohn's and Tuberculosis using CT

Crohn's disease and intestinal tuberculosis share many overlapping features such as clinical, radiological, endoscopic, and histological features - ...

Comparative Analysis of Pre-trained Deep Learning Models and DINOv2 for Cushing's Syndrome Diagnosis in Facial Analysis

Cushing's syndrome is a condition caused by excessive glucocorticoid secretion from the adrenal cortex, often manifesting with moon facies and pleth...

Quantum Hybrid Support Vector Machines for Stress Detection in Older Adults

Stress can increase the possibility of cognitive impairment and decrease the quality of life in older adults. Smart healthcare can deploy quantum ma...

Mapping and reprogramming human tissue microenvironments with MintFlow

Tissue microenvironments reprogram local cellular states in disease, yet current computational spatial methods remain descriptive and do not simulate ...

Machine-Learning-Assisted Exploration of High Entropy-Atom Nanozyme for Anti-Tumor Immunotherapy by Enhancing Enzyme Activity and Disrupting Dual Energy Metabolism

Despite its potential in cancer therapy, single-atom nanozyme (SAzyme) faces challenges like low atomic loading and rapid cancer metabolism. Here, a h...

Clinical and molecular characterisation of primary refractoriness to atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma

Despite improved outcomes with atezolizumab plus bevacizumab (A+B) in hepatocellular carcinoma (HCC), primary refractoriness (PRef), characterised by ...

Chromatin and gene-regulatory dynamics of human pulmogenesis by single cell multiomic sequencing

Human lung development is governed by complex gene regulatory networks that orchestrate cellular differentiation and organogenesis. We present a singl...

Automated generation of personalized trajectories of aging phenotypes with DyViA-GAN

With a general increase in human lifespan, the need for technological advances to develop strategies for healthy aging has assumed great importance. I...

Linking brain structure to stress reactivity: Cingulate surface area predicts acute cortisol responses

Altered stress responses are closely linked to mental disorders, but the role of brain structure in acute cortisol responses to psychosocial stress re...

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