Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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[Imaging modalities for corneal neovascularization].

Corneal neovascularization (CNV) is a frequent complication of many ocular surface diseases and represents a major threat to corneal transparency, visual function, and corneal graft survival. Accurate characterization, longitudinal monitoring, and assessment of treatment response require reliable and reproducible documentation. Numerous imaging modalities have been investigated for this purpose. R...

Mar 24 2026 41880724

Harnessing the gut microbiota in extra-intestinal cancers: from causal evidence to immunotherapy strategies.

The gut microbiota (GM) has emerged as a key modulator of cancer development and therapeutic response beyond the gastrointestinal tract. In extra-intestinal cancers, GM composition influences oncogenesis, with specific microbial taxa and their metabolites linked to either increased or decreased cancer risk, as highlighted by Mendelian Randomization studies. Beyond cancer initiation, GM plays a cri...

Mar 24 2026 41873461
Towards fair and trustworthy heart rate estimation from wrist-worn photoplethysmography: a multi-wavelength dataset and uncertainty-aware deep learning approach evaluated across skin tones, sexes, and motion conditions.

OBJECTIVE: To improve fairness (reduced disparities across skin tones and sexes) and trust (well-calibrated uncertainty metrics that indicate unreliab...

Mar 24 2026 41875538
Improving the composition of donor milk using machine learning and optimisation techniques.

BACKGROUND AND AIMS: The macronutrient composition of donor human milk (DHM) can vary substantially due to several factors such as maternal age, diet,...

Mar 24 2026 41875097
Quaternized polysaccharides: A focused review on molecular engineering, antimicrobial mechanisms, and advanced applications.

The escalating threat of antibiotic resistance has intensified the search for sustainable antimicrobial alternatives. Quaternized polysaccharides, a c...

Mar 23 2026 42002324
Severe COVID-19 in the Republic of Korea: Epidemiology, Risk Factors, Therapeutics, and Prognostic Models From Nationwide Data.

Severe coronavirus disease 2019 (COVID-19) has posed ongoing clinical and public health challenges worldwide, with Korea providing a unique perspectiv...

Mar 23 2026 41873446
TCR recognition of peptide-HLA class II complexes in autoimmunity: Structural insights for therapeutic targeting.

Autoimmune diseases encompass a broad spectrum of disorders in which self-reactive T and B cells breach immune tolerance and drive chronic tissue infl...

Mar 23 2026 41875606
Machine learning derived ORC6 as a hub biomarker for predicting tumor microenvironment, prognoses, and therapeutic responses in lung adenocarcinoma.

The origin recognition complex (ORC) is a DNA-binding complex composed of six subunits involved in DNA replication in cancer cells. The prognostic and...

Mar 23 2026 41875810
Artificial Intelligence in hepatology: A position paper by the Italian Association for the Study of the Liver.

Artificial Intelligence (AI) is transforming medicine, providing unprecedented opportunities to enhance diagnosis, prognosis, and treatment across all...

Mar 23 2026 41876274
Statistical evaluation of fresh properties of self-compacting concrete incorporating construction and industrial waste: a sustainable approach.

This study investigates the fresh properties of self-compacting concrete (SCC) developed using recycled concrete aggregates (RCA) as coarse aggregate ...

Mar 23 2026 41866650
AssayMatch: Learning To Select Data for Molecular Activity Models.

The performance of machine-learning models in drug discovery is highly dependent on the quality and consistency of the training data. Due to limitatio...

Mar 23 2026 41866971
Digital pathology platforms with integrated AI algorithms: a structured landscape analysis and recommendations for clinical implementation.

Pathology is undergoing a fundamental change as slide-based diagnostics transition toward digital workflows. Advances in whole slide imaging, data man...

Mar 23 2026 41870613
Predictive value of Hypotension Prediction Index in liver transplantation: a prospective study.

BACKGROUND: Intraoperative hypotension (IOH) is associated with increased postoperative morbidity and mortality. This prospective study evaluated the ...

Mar 23 2026 41870962
Fundamentals of big data and artificial intelligence in transfusion medicine.

Within the digital transformation of medicine, transfusion medicine has quietly become a big-data discipline. The long-standing tradition of blood pro...

Mar 23 2026 41871959
Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy.

BACKGROUND: Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic ...

Mar 22 2026 41866435
Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency.

Transfusion medicine generates enormous volumes of data across the vein-to-vein continuum, spanning donor characteristics, laboratory testing, compone...

Mar 22 2026 41866232
Precision oncology meets nanotechnology: AI-driven liposomal nanocarriers for enhanced cancer immunotherapy.

The integration of artificial intelligence (AI) with nanotechnology is redefining therapeutic strategies in cancer immunotherapy and chemotherapy. The...

Mar 21 2026 41871725
LLM-guided population-based reinforcement learning: A scalable methodology for adaptive hyperparameter optimization.

Population-Based Training (PBT) has the drawback of using fixed, pre-programmed mutation and selection rules to optimize hyperparameters, which are no...

Mar 21 2026 41953897
Integrated single-cell and bulk transcriptomics reveals STAB1 as a novel therapeutic target for ovarian cancer.

The immunosuppressive tumor microenvironment (TME) and intrinsic heterogeneity of ovarian cancer (OC) are primary drivers of therapeutic resistance an...

Mar 21 2026 41865597
Attitudes toward artificial intelligence among individuals with anxiety, depression, bipolar disorders, and schizophrenia.

BACKGROUND: Artificial intelligence (AI) increasingly supports medical diagnosis, interventions, and clinical decision-making. In various domains of h...

Mar 20 2026 41921249
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