Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Leveraging machine learning to predict de novo skin malignancy following lung transplantation.

AIMS: This study aimed to predict post-transplant malignancy risks at multiple levels among lung transplant recipients using machine learning (ML) and to identify key clinical and immunogenetic predictors. MATERIALS AND METHODS: A dataset of 30,917 lung transplant recipients with no prior cancer history was analyzed using pre-, peri-, and post-transplant variables. Multiple ML algorithms-gradient ...

Jan 19 2026 41553243

Artificial intelligence (AI)-based multi-organ contour quality assurance with uncertainty estimation for online adaptive radiotherapy (oART).

Accurate delineation of treatment targets and organs at risk (OARs) is essential to the success of radiotherapy (RT). Although artificial intelligence (AI)-based segmentation methods have successfully automated the delineation process, a reliable and efficient quality assurance (QA) mechanism is still missing, particularly in the time-critical setting of online adaptive RT (oART). This study aims ...

Jan 19 2026 41561791
Machine Learning Integrated Extracellular Vesicle Proteome Analysis For Early Markers Of Bronchopulmonary Dysplasia.

Bronchopulmonary dysplasia (BPD) is a serious and often lethal complication of pre-term birth that typically manifests about one month after pre-term ...

Jan 19 2026 41552916
Resolving energy transfer dynamics in Eu²⁺-activated multi-site phosphors via metaheuristic optimization and physics-informed neural networks.

Multi-exponential fitting has long been the standard approach for luminescence decay analysis, not because it is physically meaningful but because it ...

Jan 19 2026 41554747
Integrated multi-omics analysis of prognostic model and immune microenvironment in intrahepatic cholangiocarcinoma.

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is an aggressive malignancy originating from the epithelial lining of second-order bile ducts. Desp...

Jan 19 2026 41558145
Smart Designer Nanozymes for Precision Cancer Therapy: Recent Advances and Prospects.

Nanozymes are enzyme-mimicking nanomaterials that are promising for diverse biomedical applications; they enable stable, tunable, and multifunctional ...

Jan 17 2026 41546641
Boosting angiogenesis experimentally in ovo by biofunctionalizing collagen membranes with platelet-rich fibrin and hyaluronic acid: implications for regenerative oral surgery?

PURPOSE: Biocompatible collagen membranes (CM) are widely used in regenerative dentistry, particularly in guided tissue regeneration (GTR) and guided ...

Jan 17 2026 41546800
Lactylation-driven gene signatures define breast cancer prognosis: a predictive model and insights into immune microenvironment dynamics.

BACKGROUND: Breast cancer is a leading cause of cancer-related mortality worldwide, with poor prognosis largely due to its invasive and metastatic nat...

Jan 17 2026 41547876
Gene Modification: Exploring the potential in treating kidney diseases.

Chronic kidney disease (CKD) is a leading cause of death worldwide. Currently available drugs slow but do not cure or prevent progression to end-stage...

Jan 17 2026 41554351
Towards open-set myoelectric gesture recognition via dual-perspective inconsistency learning.

BACKGROUND AND OBJECTIVE: Gesture recognition based on surface electromyography (sEMG) has achieved significant progress in human-machine interaction ...

Jan 16 2026 41576776
A Deep Learning Model for Dynamic Prediction of Acute Kidney Injury in Heart Failure Patientss.

BACKGROUND: This study aimed to develop and validate a dynamic prediction model for acute kidney injury (AKI) in heart failure (HF) patients. METHODS:...

Jan 16 2026 41548653
Diagnostic Accuracy of the National Library of Medicine (NLM) Screener Application in Screening for Malaria Parasites Among Blood Donors at the Korle-Bu Blood Bank, Ghana: A Cross-Sectional Study.

BACKGROUND AND AIMS: Malaria is a deadly disease spread through the bite of an infected female Anopheles mosquito and remains the leading cause of mor...

Jan 16 2026 41550292
Adaptive performance control of switched nonlinear systems under false data injection attacks and input saturation constraints.

Considering the controller-actuator channel subjected to false data injection (FDI) attacks, this study proposes an adaptive performance control strat...

Jan 15 2026 41548442
[Emphasizing evolution of key technological elements in reconstructive surgery].

Reconstructive surgery is fundamentally dedicated to restoring tissues and organs damaged by trauma, disease, or congenital anomalies, with the goal o...

Jan 15 2026 41539698
Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches.

BACKGROUND: Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is ste...

Jan 15 2026 41540661
B-cell-directed Immunotherapy for Solid Tumors.

B-cell-directed immunotherapy holds great promise for treating solid tumors, where barriers such as desmoplastic stroma and low immunogenicity have li...

Jan 14 2026 41903994
Integrating CAR-T therapy with PD-1/PD-L1 blockade: Mechanisms, synergy, and optimized strategies in NSCLC.

Non-small cell lung cancer (NSCLC) presents persistent challenges in immunotherapy, as the clinical benefit of programmed cell death protein 1 (PD-1) ...

Jan 14 2026 41675056
Comprehensive review on immunotherapy for hepatocellular carcinoma: Current status and future perspectives.

Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, remains a major global health concern due to its high incidence and mort...

Jan 14 2026 41532498
Robust Physics-Based Deep MRI Reconstruction via Diffusion Purification.

Deep learning (DL) supervised techniques have been extensively employed in magnetic resonance imaging (MRI) reconstruction, delivering notable perform...

Jan 14 2026 41533627
Nerves Stimulates Crosstalk between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression.

The immunosuppressive tumor microenvironment (TME) enables cancer cells to evade clinical immunotherapies. Neural networks are vital components of the...

Jan 14 2026 41534088
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