Infectious Disease

Vaccines

Latest AI and machine learning research in vaccines for healthcare professionals.

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Deep Learning-Enhanced Hand-Driven Microfluidic Chip for Multiplexed Nucleic Acid Detection Based on RPA/CRISPR.

The early detection of high-risk human papillomavirus (HR-HPV) is crucial for the assessment and improvement of prognosis in cervical cancer. However, existing PCR-based screening methods suffer from inadequate accessibility, which dampens the enthusiasm for screening among grassroots populations, especially in resource-limited areas, and contributes to the persistently high mortality rate of cerv...

Jun 1 2025 40163382

MRI-based multimodal AI model enables prediction of recurrence risk and adjuvant therapy in breast cancer.

Timely intervention and improved prognosis for breast cancer patients rely on early metastasis risk detection and accurate treatment predictions. This study introduces an advanced multimodal MRI and AI-driven 3D deep learning model, termed the 3D-MMR-model, designed to predict recurrence risk in non-metastatic breast cancer patients. We conducted a multicenter study involving 1199 non-metastatic b...

Jun 1 2025 40345352
Model Immunization from a Condition Number Perspective

Model immunization aims to pre-train models that are difficult to fine-tune on harmful tasks while retaining their utility on other non-harmful task...

Test-Time Immunization: A Universal Defense Framework Against Jailbreaks for (Multimodal) Large Language Models

While (multimodal) large language models (LLMs) have attracted widespread attention due to their exceptional capabilities, they remain vulnerable to...

Integrating SEResNet101 and SE-VGG19 for advanced cervical lesion detection: a step forward in precision oncology.

BACKGROUND: Cervical cancer remains a significant global health issue, with accurate differentiation between low-grade (LSIL) and high-grade squamous ...

May 28 2025 40437403
RoofNet: A Global Multimodal Dataset for Roof Material Classification

Natural disasters are increasing in frequency and severity, causing hundreds of billions of dollars in damage annually and posing growing threats to...

Unveiling differential adverse event profiles in vaccines via LLM text embeddings and ontology semantic analysis.

BACKGROUND: Vaccines are crucial for preventing infectious diseases; however, they may also be associated with adverse events (AEs). Conventional anal...

May 23 2025 40410898
Prospective study using artificial neural networks for identification of high-risk COVID-19 patients.

The COVID-19 pandemic caused a major public health crisis, with severe impacts on global health and the economy. Machine learning (ML) has been crucia...

May 23 2025 40410212
Optimizing influenza vaccine allocation: A predictive analytics approach for informed public health planning.

PURPOSE: Excessive purchasing of influenza vaccine can lead to costly overages and waste of resources. Insufficient quantities, however, can jeopardiz...

May 21 2025 39520176
MMRNet: Ensemble deep learning models for predicting mismatch repair deficiency in endometrial cancer from histopathological images.

Combining molecular classification with clinicopathologic methods improves risk assessment and chooses therapies for endometrial cancer (EC). Detectin...

May 20 2025 40306276
HR-VILAGE-3K3M: A Human Respiratory Viral Immunization Longitudinal Gene Expression Dataset for Systems Immunity

Respiratory viral infections pose a global health burden, yet the cellular immune responses driving protection or pathology remain unclear. Natural ...

Mamba-Adaptor: State Space Model Adaptor for Visual Recognition

Recent State Space Models (SSM), especially Mamba, have demonstrated impressive performance in visual modeling and possess superior model efficiency...

An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study.

There are currently no licensed vaccines for norovirus, a leading cause of epidemic and endemic gastroenteritis worldwide. Clinical advancement of pro...

May 14 2025 40367195
Allocation of Oral Cholera Vaccines in Africa.

OBJECTIVES: In this study, we examine the allocation of oral cholera vaccines (OCVs) across 25 African countries between 2013 and 2019.

May 14 2025 40432128
Boosting Zero-shot Stereo Matching using Large-scale Mixed Images Sources in the Real World

Stereo matching methods rely on dense pixel-wise ground truth labels, which are laborious to obtain, especially for real-world datasets. The scarcit...

Indirect Detection of Swine Influenza Activity in Porcine Blood Using Raman Spectroscopy and Machine Learning.

Over the past decade, several swine influenza variants, including H1N1 and H1N2, have been periodically detected in swine. Raman spectroscopy (RS) off...

May 13 2025 40364571
Prognostic Value of the Brixia Radiological Score in COVID-19 Patients: A Retrospective Study from Romania.

The novel coronavirus pandemic, SARS-CoV-2, has a variable clinical spectrum, ranging from asymptomatic to critical forms. High mortality and morbidit...

May 12 2025 40423360
Fusogenic Lipid Nanovesicles as Multifunctional Immunomodulatory Platforms for Precision Solid Tumor Therapy.

Although immunotherapy demonstrates considerable prospect in overcoming solid tumors, its clinical efficacy is limited by several factors, such as poo...

May 12 2025 40351077
Application of in-silico approaches in subunit vaccines: Overcoming the challenges of antigen and adjuvant development.

Subunit vaccines are crucial in preventing modern diseases due to their safety, stability, and ability to elicit targeted immune responses. However, c...

May 10 2025 40086761
MicarVLMoE: A Modern Gated Cross-Aligned Vision-Language Mixture of Experts Model for Medical Image Captioning and Report Generation

Medical image reporting (MIR) aims to generate structured clinical descriptions from radiological images. Existing methods struggle with fine-graine...

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