Vaccines

Comparative evaluation of machine learning models for predicting COVID-19 vaccine uptake in U.S. adults.

Functional Reclassification of Lipid-Based Drug Delivery Systems and Advances in Formulation Strategies and Manufacturing Challenges.

Lipid-based drug delivery systems have progressed from a simple empirical solubilization tool towards a highly precise engineered platform, capable of delivering small drug molecules, biologics and nucleic acids. Despite proven achievements reflected through the success of lipid nanoparticles-based mRNA vaccine and siRNA medicines, wider clinical translation across complex diseases still remains l...

Deep learning-enabled scaffolding of spatial arrays of PfCSP epitopes.

Malaria is a leading cause of disease in developing countries. The licensed malaria vaccine RTS,S/AS01 confers partial protection in part due to the e...

Comparison of Artificial Intelligence Tools With Human Coding for Sentiment, Topic, and Thematic Analysis Tasks of Public Health Datasets During the COVID-19 Pandemic in Australia: Case Study.

BACKGROUND: Public opinion, which may be influenced by personal experiences, news, and social media, can impact compliance with public health measures...

Genome Database for Vaccinium: a knowledgebase for genetics, genomics, and breeding research.

The Genome Database for Vaccinium (GDV, https://www.vaccinium.org/) is a knowledgebase serving the global Vaccinium research community. GDV centralize...

mRNA-based melanoma vaccines targeting gp100 and TRP2 macromolecules.

Real-world benchmarking and validation of foundation model transformers for endometrial cancer subtyping from histopathology.

We benchmarked histopathology foundation encoders paired with attention-based multiple instance learning (MIL) against convolutional neural networks (...

Deciphering risk factors for severe postherpetic neuralgia in patients with herpes zoster: an interpretable machine learning approach.

INTRODUCTION: Postherpetic neuralgia (PHN) is a common complication of herpes zoster (HZ). This study aimed to use a large real-world electronic medic...

Efficacy of swine Influenza A virus vaccines on transmission, viral shedding and clinical signs: Systematic review and meta-analysis.

Swine influenza A viruses (swIAV) are a major cause of respiratory disease in pigs, and vaccination remains the main control strategy. The objective o...

Deterioration of immunization resilience: A Bayesian machine learning assessment of the 2025-2026 measles outbreak in Mexico.

OBJECTIVE: The 2025 measles outbreak in Mexico (5741 cases) marked a severe decline in immunization resilience. We aimed to measure this systemic vuln...

CRISPR-Cas system: recent advancements in prompt diagnosis of high-risk HPV genotypes in cervical cancer.

INTRODUCTION: The CRISPR/Cas system has emerged as a highly versatile platform for diagnosing infectious diseases, particularly viral pathogens. Human...

mRNA vaccines in cancer immunotherapy: current progress and perspectives in solid tumors and hematologic malignancies.

The unprecedented success of mRNA vaccines during the COVID-19 pandemic has accelerated the development of nucleic acid-based therapeutics, particular...

Emerging frontiers in cervical cancer diagnostics: Recent innovations in biosensors for HPV detection.

Cervical cancer (CC) is recognized as a significant health concern impacting females worldwide. The pathogenicity of CC is associated with human papil...

Neoantigen Targeting as a Novel Approach for Therapy-Resistant Tumors.

Neoantigens have emerged as central targets in the development of individualized cancer vaccines, as they are recognized by the immune system as forei...

Database of Chemicals for Organophosphorus (DCOP): An Information Application Platform for Organophosphorus Compounds.

Organophosphorus compounds (OPCs) are widely applied in diverse industries, yet their continuous release across the full life cycle poses significant ...

Cervical cancer image analysis: Detection and segmentation using self-guided quantum GANs and musical chairs optimization.

The main cause of cervical cancer emerges from long-term Human Papillomavirus (HPV) infections damaging the cervix. The detection methods produced by ...

Optimising pandemic response through vaccination strategies using neural networks.

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. Thi...

Severe COVID-19 in the Republic of Korea: Epidemiology, Risk Factors, Therapeutics, and Prognostic Models From Nationwide Data.

Severe coronavirus disease 2019 (COVID-19) has posed ongoing clinical and public health challenges worldwide, with Korea providing a unique perspectiv...

Artificial Intelligence Applications in COVID-19-Associated Coagulopathy: Lessons Learned.

Coronavirus disease 2019 (COVID-19)-associated coagulopathy (CAC) is a thromboinflammatory syndrome marked by endothelial injury, micro- and macrovasc...

Conditioning Public Opinion Perceptions by "Survey Methods 101": Informing, Engaging, and Motivating Individuals for Critical Processing of Public Opinion Polls.

Can we train individuals on survey methods to boost their critical processing of public opinion evidence? While polls are one of the most systematic a...