Neurons in cortical networks are very sparsely connected; even neurons whose axons and dendrites overlap are highly unlikely to form a synaptic connection. What is the relevance of such sparse connectivity for a network's function? Surprisingly, it h...
Topological data analysis is becoming more and more popular in recent years. It has found various applications in many different fields, for its convenience in analyzing and understanding the structure and dynamic of complex systems. We used topologi...
Connectomics is fundamental in propelling our understanding of the nervous system's organization, unearthing cells and wiring diagrams reconstructed from volume electron microscopy (EM) datasets. Such reconstructions, on the one hand, have benefited ...
INTRODUCTION: Animals such as cattle can achieve versatile and elegant behaviors through automatic sensorimotor coordination. Their self-organized movements convey an impression of adaptability, robustness, and motor memory. However, the adaptive mec...
Understanding the real-time dynamical mechanisms of neural systems remains a significant issue, preventing the development of efficient neural technology and user trust. This is because the mechanisms, involving various neural spatial-temporal ingred...
Existing adaptive locomotion control mechanisms for legged robots are usually aimed at one specific type of adaptation and rarely combined with others. Adaptive mechanisms thus stay at a conceptual level without their coupling effect with other mecha...
Working memory function is severely limited. One key limitation that constrains the ability to maintain multiple items in working memory simultaneously is so-called swap errors. These errors occur when an inaccurate response is in fact accurate relat...
The tri-synaptic pathway in the mammalian hippocampus enables cognitive learning and memory. Despite decades of reports on anatomy and physiology, the functional architecture of the hippocampal network remains poorly understood in terms of the dynami...
In the prefrontal cortex (PFC), higher-order cognitive functions and adaptive flexible behaviors rely on continuous dynamical sequences of spiking activity that constitute neural trajectories in the state space of activity. Neural trajectories subser...
The mechanisms involved in generation of rhythmic locomotor activity in the mammalian spinal cord remain poorly understood. These mechanisms supposedly rely on both intrinsic properties of constituting neurons and interactions between them. A subset ...