Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Aug 5, 2020
The Gleason score is the most important prognostic marker for prostate cancer patients, but it suffers from significant observer variability. Artificial intelligence (AI) systems based on deep learning can achieve pathologist-level performance at Gle...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
May 28, 2020
Pathologists are responsible for rapidly providing a diagnosis on critical health issues. Challenging cases benefit from additional opinions of pathologist colleagues. In addition to on-site colleagues, there is an active worldwide community of patho...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
May 11, 2020
Prostate cancer (PrCa) is the second most common cancer among men in the United States. The gold standard for detecting PrCa is the examination of prostate needle core biopsies. Diagnosis can be challenging, especially for small, well-differentiated ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Apr 1, 2020
Immunohistochemistry (IHC) is a diagnostic technique used throughout pathology. A machine learning algorithm that could predict individual cell immunophenotype based on hematoxylin and eosin (H&E) staining would save money, time, and reduce tissue co...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Mar 26, 2020
A deep learning-based image analysis could improve diagnostic accuracy and efficiency in pathology work. Recently, we proposed a deep learning-based detection algorithm for C4d immunostaining in renal allografts. The objective of this study is to ass...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Dec 16, 2019
Tumor budding is a promising and cost-effective biomarker with strong prognostic value in colorectal cancer. However, challenges related to interobserver variability persist. Such variability may be reduced by immunohistochemistry and computer-aided ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jun 13, 2018
The breast stromal microenvironment is a pivotal factor in breast cancer development, growth and metastases. Although pathologists often detect morphologic changes in stroma by light microscopy, visual classification of such changes is subjective and...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Mar 1, 2023
Image analysis assistance with artificial intelligence (AI) has become one of the great promises over recent years in pathology, with many scientific studies being published each year. Nonetheless, and perhaps surprisingly, only few image AI systems ...