AIMC Topic: Adenocarcinoma of Lung

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3D multi-scale, multi-task, and multi-label deep learning for prediction of lymph node metastasis in T1 lung adenocarcinoma patients' CT images.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
The diagnosis of preoperative lymph node (LN) metastasis is crucial to evaluate possible therapy options for T1 lung adenocarcinoma patients. Radiologists preoperatively diagnose LN metastasis by evaluating signs related to LN metastasis, like spicul...

Highly accurate diagnosis of lung adenocarcinoma and squamous cell carcinoma tissues by deep learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Intraoperative detection of the marginal tissues is the last and most important step to complete the resection of adenocarcinoma and squamous cell carcinoma. However, the current intraoperative diagnosis is time-consuming and requires numerous steps ...

Selection, Visualization, and Interpretation of Deep Features in Lung Adenocarcinoma and Squamous Cell Carcinoma.

The American journal of pathology
Although deep learning networks applied to digital images have shown impressive results for many pathology-related tasks, their black-box approach and limitation in terms of interpretability are significant obstacles for their widespread clinical uti...

Cancer-associated fibroblasts are associated with poor prognosis in solid type of lung adenocarcinoma in a machine learning analysis.

Scientific reports
Cancer-associated fibroblasts (CAFs) participate in critical processes in the tumor microenvironment, such as extracellular matrix remodeling, reciprocal signaling interactions with cancer cells and crosstalk with infiltrating inflammatory cells. How...

Comparative analysis of machine learning approaches to classify tumor mutation burden in lung adenocarcinoma using histopathology images.

Scientific reports
Both histologic subtypes and tumor mutation burden (TMB) represent important biomarkers in lung cancer, with implications for patient prognosis and treatment decisions. Typically, TMB is evaluated by comprehensive genomic profiling but this requires ...

Resolution-based distillation for efficient histology image classification.

Artificial intelligence in medicine
Developing deep learning models to analyze histology images has been computationally challenging, as the massive size of the images causes excessive strain on all parts of the computing pipeline. This paper proposes a novel deep learning-based method...

Machine learning applied to near-infrared spectra for clinical pleural effusion classification.

Scientific reports
Lung cancer patients with malignant pleural effusions (MPE) have a particular poor prognosis. It is crucial to distinguish MPE from benign pleural effusion (BPE). The present study aims to develop a rapid, convenient and economical diagnostic method ...

Digital/Computational Technology for Molecular Cytology Testing: A Short Technical Note with Literature Review.

Acta cytologica
This short article describes the method of digital cytopathology using Z-stack scanning with or without extended focusing. This technology is suitable to observe such thick clusters as adenocarcinoma on cytologic specimens. Artificial intelligence (A...

Computer-aided diagnosis of ground glass pulmonary nodule by fusing deep learning and radiomics features.

Physics in medicine and biology
OBJECTIVES: This study aims to develop a computer-aided diagnosis (CADx) scheme to classify between benign and malignant ground glass nodules (GGNs), and fuse deep leaning and radiomics imaging features to improve the classification performance.

Denoising Autoencoder, A Deep Learning Algorithm, Aids the Identification of A Novel Molecular Signature of Lung Adenocarcinoma.

Genomics, proteomics & bioinformatics
Precise biomarker development is a key step in disease management. However, most of the published biomarkers were derived from a relatively small number of samples with supervised approaches. Recent advances in unsupervised machine learning promise t...