IEEE journal of biomedical and health informatics
Jul 16, 2018
Optical coherence tomography (OCT) is a high-resolution and noninvasive imaging modality that has become one of the most prevalent techniques for ophthalmic diagnosis. Retinal layer segmentation is very crucial for doctors to diagnose and study retin...
In silico models are presented for modeling and predicting thyroid hormone receptor (TR) agonists and antagonists. A data set consisting of 258 compounds is used in the present work. The C4.5, random forest (RF) and support vector machine (SVM) stati...
With the advancement in drug development, multiple treatments are available for a single disease. Patients can often benefit from taking multiple treatments simultaneously. For example, patients in Clinical Practice Research Datalink with chronic dis...
Key challenges for human genetics, precision medicine and evolutionary biology include deciphering the regulatory code of gene expression and understanding the transcriptional effects of genome variation. However, this is extremely difficult because ...
International journal of molecular sciences
Jul 16, 2018
Amyloid is an insoluble fibrous protein and its mis-aggregation can lead to some diseases, such as Alzheimer's disease and Creutzfeldt⁻Jakob's disease. Therefore, the identification of amyloid is essential for the discovery and understanding of disea...
Exploring and detecting the causal relations among variables have shown huge practical values in recent years, with numerous opportunities for scientific discovery, and have been commonly seen as the core of data science. Among all possible causal di...
BACKGROUND: Public biomedical data repositories often provide web-based interfaces to collect experimental metadata. However, these interfaces typically reflect the ad hoc metadata specification practices of the associated repositories, leading to a ...
Electromyogram (EMG) signal decoding is the essential part of myoelectric control. However, traditional machine learning methods lack the capability of learning and expressing the information contained in EMG signals, and the robustness of the myoele...
Medical & biological engineering & computing
Jul 12, 2018
With the advent of biomedical imaging technology, the number of captured and stored biomedical images is rapidly increasing day by day in hospitals, imaging laboratories and biomedical institutions. Therefore, more robust biomedical image analysis te...
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