MOTIVATION: Spatial transcriptomics (ST) addresses the loss of spatial context in single-cell RNA-sequencing by simultaneously capturing gene expression and spatial location information. A critical task of ST is the identification of spatial domains....
MOTIVATION: Leveraging deep learning for the representation learning of Gene Ontology (GO) and Gene Ontology Annotation (GOA) holds significant promise for enhancing downstream biological tasks such as protein-protein interaction prediction. Prior ap...
MOTIVATION: The integration of Machine Learning and Artificial Intelligence (AI) into healthcare has immense potential due to the rapidly growing volume of clinical data. However, existing AI models, particularly Large Language Models (LLMs) like GPT...
MOTIVATION: Identifying drug-target interactions (DTIs) is a crucial step in drug repurposing and drug discovery. The significant increase in demand and the expensive nature for experimentally identifying DTIs necessitate computational tools for auto...
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Mar 28, 2025
AIMS: The aim of this study was to perform an external validation of an automatic machine learning (ML) algorithm for heart rhythm diagnostics using smartphone photoplethysmography (PPG) recorded by patients with atrial fibrillation (AF) and atrial f...
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Mar 25, 2025
Proteins are the basic building blocks of life. Studying the protein expression mechanism is essential for understanding the cellular organization principles and the development of biotechnology. Protein expression, involving transcription, translati...
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Mar 25, 2025
Synthetic biology is an emerging interdisciplinary field at the convergence of biology, engineering, and computer science. It employs a bottom-up approach to progressively design biological parts, devices, and circuits, aiming to create artificial bi...
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Mar 25, 2025
Natural components serve the survival instincts of cells that are obtained through long-term evolution, while they often fail to meet the demands of engineered cells for efficiently performing biological functions in special industrial environments. ...
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Mar 25, 2025
Nucleic acid elements are essential functional sequences that play critical roles in regulating gene expression, optimizing pathways, and enabling gene editing to enhance the production of target products in biomanufacturing. Therefore, the design an...
The aim of this study was to devise a machine learning algorithm with superior performance in predicting bone metastasis (BM) in small cell lung cancer (SCLC) and create a straightforward web-based predictor based on the developed algorithm. Data com...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.