AIMC Topic: Alzheimer Disease
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Predicting cognitive decline: Deep-learning reveals subtle brain changes in pre-MCI stage.
The journal of prevention of Alzheimer's disease
Feb 6, 2025
BACKGROUND: Mild cognitive impairment (MCI) and preclinical MCI (e.g., subjective cognitive decline, SCD) are considered risk states of dementia, such as Alzheimer's Disease (AD). However, it is challenging to accurately predict conversion from norma...
Community Graph Convolution Neural Network for Alzheimer's Disease Classification and Pathogenetic Factors Identification.
IEEE transactions on neural networks and learning systems
Feb 6, 2025
As a complex neural network system, the brain regions and genes collaborate to effectively store and transmit information. We abstract the collaboration correlations as the brain region gene community network (BG-CN) and present a new deep learning a...
Joint ensemble learning-based risk prediction of Alzheimer's disease among mild cognitive impairment patients.
The journal of prevention of Alzheimer's disease
Feb 5, 2025
OBJECTIVE: Due to the recognition for the importance of early intervention in Alzheimer's disease (AD), it is important to focus on prevention and treatment strategies for mild cognitive impairment (MCI). This study aimed to establish a risk predicti...
Detection of Alzheimer Disease in Neuroimages Using Vision Transformers: Systematic Review and Meta-Analysis.
Journal of medical Internet research
Feb 5, 2025
BACKGROUND: Alzheimer disease (AD) is a progressive condition characterized by cognitive decline and memory loss. Vision transformers (ViTs) are emerging as promising deep learning models in medical imaging, with potential applications in the detecti...
Multi-knowledge informed deep learning model for multi-point prediction of Alzheimer's disease progression.
Neural networks : the official journal of the International Neural Network Society
Feb 1, 2025
The diagnosis of Alzheimer's disease (AD) based on visual features-informed by clinical knowledge has achieved excellent results. Our study endeavors to present an innovative and detailed deep learning framework designed to accurately predict the pro...
HEDDI-Net: heterogeneous network embedding for drug-disease association prediction and drug repurposing, with application to Alzheimer's disease.
Journal of translational medicine
Feb 1, 2025
BACKGROUND: The traditional process of developing new drugs is time-consuming and often unsuccessful, making drug repurposing an appealing alternative due to its speed and safety. Graph neural networks (GCNs) have emerged as a leading approach for pr...
Integrating neuroscience and artificial intelligence: EEG analysis using ensemble learning for diagnosis Alzheimer's disease and frontotemporal dementia.
Journal of neuroscience methods
Jan 31, 2025
BACKGROUND: Alzheimer's disease (AD) and frontotemporal dementia (FTD) are both progressive neurological disorders that affect the elderly. Distinguishing between individuals suffering from these two diseases in the early stages can be quite challeng...
Identification of therapeutic targets for Alzheimer's Disease Treatment using bioinformatics and machine learning.
Scientific reports
Jan 31, 2025
Alzheimer's disease (AD) is a complex neurodegenerative disorder that currently lacks effective treatment options. This study aimed to identify potential therapeutic targets for the treatment of AD using comprehensive bioinformatics methods and machi...
Predicting conversion in cognitively normal and mild cognitive impairment individuals with machine learning: Is the CSF status still relevant?
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jan 30, 2025
INTRODUCTION: Machine learning (ML) helps diagnose the mild cognitive impairment-Alzheimer's disease (MCI-AD) spectrum. However, ML is fed with data unavailable in standard clinical practice. Thus, we tested a novel multi-step ML approach to predict ...
Preclinical Cognitive Markers of Alzheimer Disease and Early Diagnosis Using Virtual Reality and Artificial Intelligence: Literature Review.
JMIR medical informatics
Jan 28, 2025
BACKGROUND: This review explores the potential of virtual reality (VR) and artificial intelligence (AI) to identify preclinical cognitive markers of Alzheimer disease (AD). By synthesizing recent studies, it aims to advance early diagnostic methods t...
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