AIMC Topic: Antiparkinson Agents

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Overground robot assisted gait trainer for the treatment of drug-resistant freezing of gait in Parkinson disease.

Journal of the neurological sciences May 29, 2015
Freezing of Gait (FOG) is a frequent and disabling feature of Parkinson disease (PD). Gait rehabilitation assisted by electromechanical devices, such as training on treadmill associated with sensory cues or assisted by gait orthosis have been shown t...
Statistics, Nonparametric Gait Disorders, Neurologic Exercise Therapy Antiparkinson Agents Parkinson Disease Robotics Male Female Middle Aged Aged Humans Treatment Outcome
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Supervised machine learning and molecular docking modeling to identify potential Anti-Parkinson's agents.

Journal of molecular graphics & modelling Sep 1, 2025
Parkinson's disease is a neurodegenerative condition that affects the brain's neurons, and causes malfunction of nerve cells and their death. A neurotransmitter called dopamine interacts with the part of the brain in charge of coordination and moveme...
Machine Learning Molecular Docking Simulation Protein Binding Humans Ligands Parkinson Disease Antiparkinson Agents Supervised Machine Learning Receptor, Adenosine A2A
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Medication versus globus pallidus internus deep brain stimulation in Parkinson's disease with deep learning video analysis of finger tapping.

Scientific reports May 21, 2025
In advanced Parkinson's disease (PD), considerable number of patients receive deep brain stimulation (DBS) surgery, to alleviate symptoms not readily controlled by medication. However, the differential effects of medication and DBS on improving motor...
Humans Female Aged Globus Pallidus Deep Brain Stimulation Deep Learning Video Recording Parkinson Disease Antiparkinson Agents Male Fingers Hypokinesia Middle Aged
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Optimizing Neuroprotective Nano-structured Lipid Carriers for Transdermal Delivery through Artificial Neural Network.

Pharmaceutical nanotechnology Jan 1, 2025
BACKGROUND: Dementia associated with Alzheimer's disease (AD) is a neurological disorder. AD is a progressive neurodegenerative condition that predominantly impacts the elderly population, although it can also manifest in younger people through the i...
Administration, Cutaneous Antiparkinson Agents Nootropic Agents Alzheimer Disease Nanostructures Donepezil Memantine Neural Networks, Computer Computer Simulation Neuroprotective Agents Drug Carriers Dementia Humans
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Effectiveness of robot-assisted gait training on motor impairments in people with Parkinson's disease: a systematic review and meta-analysis.

International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation Dec 1, 2018
The aim of this systematic review and meta-analysis was to evaluate the effectiveness of robot-assisted gait training (RAGT) on motor impairments in people with Parkinson's disease (PD). A computer-based systematic literature search was performed in ...
Neurologic Examination Female Antiparkinson Agents Robotics Aged Gait Disorders, Neurologic Postural Balance Humans Exercise Therapy Outcome Assessment, Health Care Combined Modality Therapy Aged, 80 and over Treatment Outcome Middle Aged Male Parkinson Disease
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Towards an expert system for accurate diagnosis and progress monitoring of Parkinson's disease.

Advances in experimental medicine and biology Jan 1, 2015
While Parkinson's disease is a chronic and progressive movement disorder, no one can predict which symptoms will affect an individual patient. At the present time there is no cure for Parkinson's disease but instead a variety of alternative treatment...
Carbidopa Disease Progression Parkinson Disease Antiparkinson Agents Biomarkers Humans Expert Systems Deep Brain Stimulation Levodopa Sensitivity and Specificity Drug Therapy, Combination Algorithms
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