AIMC Topic: Axons

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Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning.

NeuroImage Jun 1, 2025
Short-range association fibers located in the superficial white matter play an important role in mediating higher-order cognitive function in humans. Detailed morphological characterization of short-range association fibers at the microscopic level p...
Deep Learning Imaging, Three-Dimensional Adult Male Microscopy, Electron, Scanning White Matter Nerve Fibers, Myelinated Humans Image Processing, Computer-Assisted Female Axons
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Artificial Axon with Dendritic-like Plasticity by Biomimetic Interface Engineering of Anisotropic Two-Dimensional Tellurium.

Nano letters May 28, 2025
Spiking neural network (SNN) hardware relies on implicit assumptions that prioritize dendritic/synaptic learning above axon/synaptic concerns, compromising performances in signal capacity, accuracy, and compactness of SNN systems. Herein, we develop ...
Neural Networks, Computer Biomimetic Materials Dendrites Anisotropy Neuronal Plasticity Tellurium Biomimetics Axons
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AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons.

Translational vision science & technology Mar 1, 2023
PURPOSE: Assessment of glaucomatous damage in animal models is facilitated by rapid and accurate quantification of retinal ganglion cell (RGC) axonal loss and morphologic change. However, manual assessment is extremely time- and labor-intensive. Here...
Deep Learning Mice Cross-Sectional Studies Animals Axons Retinal Ganglion Cells Rats Disease Models, Animal Glaucoma
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AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning.

Translational vision science & technology Dec 1, 2021
PURPOSE: Optic nerve damage is the principal feature of glaucoma and contributes to vision loss in many diseases. In animal models, nerve health has traditionally been assessed by human experts that grade damage qualitatively or manually quantify axo...
Mice Optic Nerve Optic Nerve Injuries Axons Animals Deep Learning Glaucoma
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Propagation delays determine neuronal activity and synaptic connectivity patterns emerging in plastic neuronal networks.

Chaos (Woodbury, N.Y.) Oct 1, 2018
In plastic neuronal networks, the synaptic strengths are adapted to the neuronal activity. Specifically, spike-timing-dependent plasticity (STDP) is a fundamental mechanism that modifies the synaptic strengths based on the relative timing of pre- and...
Dendrites Synapses Computer Simulation Algorithms Time Factors Axons Humans Oscillometry Brain Nerve Net Nonlinear Dynamics Neural Networks, Computer Models, Neurological Synaptic Transmission Plastics Neuronal Plasticity Normal Distribution Action Potentials Neurons
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Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.

Advances in experimental medicine and biology Jan 1, 2016
Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on its ensheathing Schwann cell (SC), the axon-SC unit. We review evidence in several fields and show ...
Cell Communication Axons RNA, Messenger Biological Transport Phenotype Rats Ribosomes Exosomes Signal Transduction Humans Animals Schwann Cells Action Potentials Microtubules Neural Networks, Computer Sural Nerve Nerve Regeneration
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